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Association Between Alzheimer Disease and Amyotrophic Lateral Sclerosis?

Published online by Cambridge University Press:  18 September 2015

M.F. Frecker*
Affiliation:
Division of Neurology, Faculty of Medicine, Memorial University, St. John's, Newfoundland
F.C Fraser
Affiliation:
Centre for Human Genetics, McGill University, Montreal
E. Andermann
Affiliation:
Centre for Human Genetics, McGill University, Montreal Neurogenetics Unit, Montreal Neurological Hospital and Institute, Montreal
W.E.M. Pryse-Phillips
Affiliation:
Division of Neurology, Faculty of Medicine, Memorial University, St. John's, Newfoundland
*
Division of Neurology, Faculty of Medicine, Memorial University, St. John's, Newfoundland, Canada AlB 3V6
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Abstract:

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We report two cases of Alzheimer disease (AD) — one of them familial — in which the patient also had amyotrophic lateral sclerosis (ALS), and one patient with familial AD who had a son with ALS. Three further cases of probable ALS were found in pedigrees of AD reported from the literature. It is proposed that this association is not coincidental, but may suggest an etiological factor in common.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1990

References

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