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Current Trends in Neurosurgical Management of Adult Diffuse Low-Grade Gliomas in Canada

Published online by Cambridge University Press:  05 May 2022

Mostafa Fatehi
Affiliation:
Division of Neurosurgery, University of British Columbia, Vancouver, BC, Canada
Leeor S. Yefet*
Affiliation:
Division of Neurosurgery, University of British Columbia, Vancouver, BC, Canada
Swetha Prakash
Affiliation:
Division of Neurosurgery, University of British Columbia, Vancouver, BC, Canada
Brian D. Toyota
Affiliation:
Division of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA
Peter A. Gooderham
Affiliation:
Division of Neurosurgery, University of British Columbia, Vancouver, BC, Canada
*
Corresponding author: Leeor S. Yefet, University of British Columbia, Vancouver, BC, Canada. Email: lyefet@alumni.ubc.ca

Abstract:

There is considerable variability in the management of diffuse low-grade gliomas (LGGs). To characterize treatment paradigms, a survey of Canadian neurosurgeons was performed with forty neurosurgeons responding. Their responses show that the management of patients with LGGs has evolved in the past decade and findings from the RTOG9802 trial have been integrated into the practice of Canadian neurosurgeons. Most respondents stated that the patient selection and treatment strategy advocated by the RTOG9802 trial needs further evaluation. Overall, there is a trend toward more aggressive surgical resections, and future investigations will have to more accurately stratify patient risk profiles.

Résumé:

RÉSUMÉ:

Tendances actuelles concernant la prise en charge neurochirurgicale des gliomes diffus de faible degré chez les adultes au Canada.

Il existe des divergences considérables quant à la prise en charge des gliomes diffus de faible degré. Afin de décrire les paradigmes de traitement, un sondage a été mené parmi les neurochirurgiens au Canada, dont 40 y ont participé. Leurs réponses montrent que la prise en charge des patients atteints de ce type de gliome a évolué au cours de la dernière décennie, et que les résultats de l’étude RTOG9802 ont été intégrés dans la pratique des neurochirurgiens au Canada. La plupart des répondants ont indiqué que la sélection des patients et la stratégie de traitement préconisées dans l’étude RTOG9802 doivent faire l’objet d’une évaluation plus approfondie. Dans l’ensemble, on observe une tendance à recourir à des résections chirurgicales plus radicales, et il faut mener d’autres recherches afin de catégoriser avec plus de précision les profils de risque des patients.

Type
Brief Communication
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of Canadian Neurological Sciences Federation

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