1 Rayman, MP (2000) The importance of selenium to human health. Lancet 356, 233–241.
2 Ip, C (1986) The chemopreventive role of selenium in carcinogenesis. Adv Exp Med Biol 206, 431–447.
3 Hussein, O, Rosenblat, M, Refael, G & Aviram, M (1997) Dietary selenium increases cellular glutathione peroxidase activity and reduces the enhanced susceptibility to lipid peroxidation of plasma and low-density lipoprotein in kidney transplant recipients. Transplantation 63, 679–685.
4 Traulsen, H, Steinbrenner, H, Buchczyk, DP, Klotz, LO & Sies, H (2004) Selenoprotein P protects low-density lipoprotein against oxidation. Free Radic Res 38, 123–128.
5 Wadkar-Navsariwala, V, Prins, GS, Swanson, SM, Birch, LA, Ray, VH, Hedayat, S, Lantvit, DL & Diamond, AM (2006) Selenoprotein deficiency accelerates prostate carcinogenesis in a transgenic model. Proc Natl Acad Sci U S A 103, 8179–8184.
6 Saito, Y, Sato, N, Hirashima, M, Takebe, G, Nagasawa, S & Takahashi, K (2004) Domain structure of bi-functional selenoprotein P. Biochem J 381, 841–846.
7 Ratnasinghe, D, Tangrea, JA, Andersen, MR, Barrett, MJ, Virtamo, J, Taylor, PR & Albanes, D (2000) Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. Cancer Res 60, 6381–6383.
8 Hu, YJ & Diamond, AM (2003) Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res 63, 3347–3351.
9 Ravn-Haren, G, Olsen, A, Tjonneland, A, Dragsted, LO, Nexo, BA, Wallin, H, Overvad, K, Raaschou- Nielsen, O & Vogel, U (2006) Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis 27, 820–825.
10 Thomson, CD, Burton, CE & Robinson, M (1978) On supplementing the selenium intake of New Zealanders. 1. Short experiments with large doses of selenite or selenomethionine. Br J Nutr 39, 579–587.
11 Thomson, CD, Robinson, MF, Campbell, DR & Rea, HM (1982) Effect of prolonged supplementation with daily supplements of selenomethionine and sodium selenite on glutathione peroxidase activity in blood of New Zealand residents. Am J Clin Nutr 36, 24–31.
12 Levander, OA, Alfthan, G, Arvilommi, H, Gref, CG, Huttunen, JK, Kataja, M, Koivistoinen, P & Pikkarainen, J (1983) Bioavailability of selenium to Finnish men as assessed by platelet glutathione peroxidase activity and other blood parameters. Am J Clin Nutr 37, 887–897.
13 Thomson, CD, Robinson, MF, Butler, JA & Whanger, PD (1993) Long-term supplementation with selenate and selenomethionine: selenium and glutathione peroxidase (EC 220.127.116.11) in blood components of New Zealand women. Br J Nutr 69, 577–588.
14 Alfthan, G, Aro, A, Arvilommi, H & Huttunen, JK (1991) Selenium metabolism and platelet glutathione peroxidase activity in healthy Finnish men: effects of selenium yeast, selenite, and selenate. Am J Clin Nutr 53, 120–125.
15 Neve, J (1995) Human selenium supplementation as assessed by changes in blood selenium concentration and glutathione peroxidase activity. J Trace Elem Med Biol 9, 65–73.
16 Neve, J, Vertongen, F & Capel, P (1988) Selenium supplementation in healthy Belgian adults: response in platelet glutathione peroxidase activity and other blood indices. Am J Clin Nutr 48, 139–143.
17 Butler, JA, Thomson, CD, Whanger, PD & Robinson, MF (1991) Selenium distribution in blood fractions of New Zealand women taking organic or inorganic selenium. Am J Clin Nutr 53, 748–754.
18 Thomson, CD, Steven, SM, van Rij, AM, Wade, CR & Robinson, MF (1988) Selenium and vitamin E supplementation: activities of glutathione peroxidase in human tissues. Am J Clin Nutr 48, 316–323.
19 van der Torre, HW, Van, DW, Schaafsma, G, Wedel, M & Ockhuizen, T (1991) Effect of various levels of selenium in wheat and meat on blood Se status indices and on Se balance in Dutch men. Br J Nutr 65, 69–80.
20 Fox, TE, Van den Heuvel, EG, Atherton, CA, et al. (2004) Bioavailability of selenium from fish, yeast and selenate: a comparative study in humans using stable isotopes. Eur J Clin Nutr 58, 343–349.
21 Lyhne, N, Christensen, T, Groth, MV, et al. Danskernes Kostvaner 2000-2002. Hovedresultater, Søborg, Denmark: Danish Institute for Food and Veterinary Research.
22 Chen, J, Lindmark-Mansson, H, Drevelius, M, Tidehag, P, Hallmans, G, Hertervig, E, Nilsson, A & Akesson, B (2004) Bioavailability of selenium from bovine milk as assessed in subjects with ileostomy. Eur J Clin Nutr 58, 350–355.
23 El Bayoumy, K & Sinha, R (2005) Molecular chemoprevention by selenium: a genomic approach. Mutat Res 591, 224–236.
24 Gipp, JJ, Chang, C & Mulcahy, RT (1992) Cloning and nucleotide sequence of a full-length cDNA for human liver γ-glutamylcysteine synthetase. Biochem Biophys Res Commun 185, 29–35.
25 Gipp, JJ, Bailey, HH & Mulcahy, RT (1995) Cloning and sequencing of the cDNA for the light subunit of human liver γ-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues. Biochem Biophys Res Commun 206, 584–589.
26 Chen, C & Kong, AN (2004) Dietary chemopreventive compounds and ARE/EpRE signaling. Free Radic Biol Med 36, 1505–1516.
27 Venugopal, R & Jaiswal, AK (1996) Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci U S A 93, 14960–14965.
28 Jardine, H, MacNee, W, Donaldson, K & Rahman, I (2002) Molecular mechanism of transforming growth factor (TGF)-β1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J Biol Chem 277, 21158–21166.
29 Hercberg, S, Bertrais, S, Czernichow, S, et al. (2005) Alterations of the lipid profile after 7.5 years of low-dose antioxidant supplementation in the SU.VI.MAX Study. Lipids 40, 335–342.
30 Andersen, LT, Jensen, H & Haraldsdottir, J (1996) Typiske vægte for madvarer (Typical weights for foods). Scand J Nutr 4, S129–S152.
31 Sloth, JJ, Larsen, EH, Bugel, SH & Moesgaard, S (2003) Determination of total selenium and Se-77 in isotopically enriched human samples by ICP-dynamic reaction cell-MS. J Anal At Spectrom 18, 317–322.
32 Pruszkowski, E (2004) Selenium Determination in Blood and Serum with ICP-MS. Waltham, MA: PerkinElmer.
33 Mayer, B, Schumacher, M, Brandstatter, H, Wagner, FS & Hermetter, A (2001) High-throughput fluorescence screening of antioxidative capacity in human serum. Anal Biochem 297, 144–153.
34 Wheeler, CR, Salzman, JA, Elsayed, NM, Omaye, ST & Korte, DW Jr (1990) Automated assays for superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity. Anal Biochem 184, 193–199.
35 Dragsted, LO, Pedersen, A, Hermetter, A, et al. (2004) The 6-a-day study: effects of fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. Am J Clin Nutr 79, 1060–1072.
36 Pedersen, A (1993) , Master's Thesis, Royal Vetarinary and Agricultural University, Frederiksberg, Denmark.
37 Jørgensen, K (2005) , Master's Thesis, Royal Veterinary and Agricultural University, Frederiksberg, Denmark.
38 Burk, RF, Norsworthy, BK, Hill, KE, Motley, AK & Byrne, DW (2006) Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial. Cancer Epidemiol Biomarkers Prev 15, 804–810.
39 Fox, TE, Atherton, C, Dainty, JR, Lewis, DJ, Langford, NJ, Baxter, MJ, Crews, HM & Fairweather-Tait, SJ (2005) Absorption of selenium from wheat, garlic, and cod intrinsically labeled with Se-77 and Se-82 stable isotopes. Int J Vitam Nutr Res 75, 179–186.
40 Mutanen, M (1986) Bioavailability of selenium in mushrooms, Boletus edulis, to young women. Int J Vitam Nutr Res 56, 297–301.
41 Bugel, SH, Sandstrom, B & Larsen, EH (2001) Absorption and retention of selenium from shrimps in man. J Trace Elem Med Biol 14, 198–204.
42 Bugel, S, Sandstrom, B & Skibsted, LH (2004) Pork meat: a good source of selenium? J Trace Elem Med Biol 17, 307–311.
43 Tarp, U, Hansen, JC, Overvad, K, Thorling, EB, Tarp, BD & Graudal, H (1987) Glutathione peroxidase activity in patients with rheumatoid arthritis and in normal subjects: effects of long-term selenium supplementation. Arthritis Rheum 30, 1162–1166.
44 Alfthan, G, Xu, GL, Tan, WH, Aro, A, Wu, J, Yang, YX, Liang, WS, Xue, WL & Kong, LH (2000) Selenium supplementation of children in a selenium-deficient area in China: blood selenium levels and glutathione peroxidase activities. Biol Trace Elem Res 73, 113–125.
45 Van Dael, P, Davidsson, L, Munoz-Box, R, Fay, LB & Barclay, D (2001) Selenium absorption and retention from a selenite- or selenate-fortified milk-based formula in men measured by a stable-isotope technique. Br J Nutr 85, 157–163.
46 Xia, Y, Hill, KE, Byrne, DW, Xu, J & Burk, RF (2005) Effectiveness of selenium supplements in a low-selenium area of China. Am J Clin Nutr 81, 829–834.
47 El-Sayed, WM, boul-Fadl, T, Lamb, JG, Roberts, JC & Franklin, MR (2006) Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice. Toxicology 220, 179–188.
48 Helmersson, J, Arnlov, J, Vessby, B, Larsson, A, Alfthan, G & Basu, S (2005) Serum selenium predicts levels of F2-isoprostanes and prostaglandin F2α in a 27 year follow-up study of Swedish men. Free Radic Res 39, 763–770.
49 Stranges, S, Marshall, JR, Trevisan, M, Natarajan, R, Donahue, RP, Combs, GF, Farinaro, E, Clark, LC & Reid, ME (2006) Effects of selenium supplementation on cardiovascular disease incidence and mortality: secondary analyses in a randomized clinical trial. Am J Epidemiol 163, 694–699.
50 Maehira, F, Luyo, GA, Miyagi, I, Oshiro, M, Yamane, N, Kuba, M & Nakazato, Y (2002) Alterations of serum selenium concentrations in the acute phase of pathological conditions. Clin Chim Acta 316, 137–146.
51 Mayland, C, Allen, KR, Degg, TJ & Bennet, M (2004) Micronutrient concentrations in patients with malignant disease: effect of the inflammatory response. Ann Clin Biochem 41, 138–141.
52 Ghayour-Mobarhan, M, Taylor, A, New, SA, Lamb, DJ & Ferns, GA (2005) Determinants of serum copper, zinc and selenium in healthy subjects. Ann Clin Biochem 42, 364–375.