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A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer: pilot study of the Prostate Cancer Weight Management (PRO-MAN) randomised controlled trial

  • H. Mohamad (a1), M. Ntessalen (a1), L. C. A. Craig (a1) (a2), J. Clark (a3), S. Fielding (a4), J. N’Dow (a5), S. D. Heys (a6) and G. McNeill (a1)...

Abstract

Overweight and obesity may increase risk of disease progression in men with prostate cancer, but there have been few studies of weight loss interventions in this patient group. In this study overweight or obese men treated for prostate cancer were randomised to a self-help diet and activity intervention with telephone-based dietitian support or a wait-list mini-intervention group. The intervention group had an initial group meeting, a supporting letter from their urological consultant, three telephone dietitian consultations at 4-week intervals, a pedometer and access to web-based diet and physical activity resources. At 12 weeks, men in both groups were given digital scales for providing follow-up weight measurements, and the wait-list group received a mini-intervention of the supporting letter, a pedometer and access to the web-based resources. Sixty-two men were randomised; fifty-four completed baseline and 12-week measurements, and fifty-one and twenty-seven provided measurements at 6 and 12 months, respectively. In a repeated-measures model, mean difference in weight change between groups (wait-list mini-intervention minus intervention) at 12 weeks was −2·13 (95 % CI −3·44, −0·82) kg (P = 0·002). At 12 months the corresponding value was −2·43 (95 % CI −4·50, −0·37) kg (P = 0·022). Mean difference in global quality of life score change between groups at 12 weeks was 12·3 (95 % CI 4·93, 19·7) (P = 0·002); at 12 months there were no significant differences between groups. Results suggest the potential of self-help diet and physical activity intervention with trained support for modest but sustained weight loss in this patient group.

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Corresponding author

*Corresponding author: Dr Leone Craig, email l.craig@abdn.ac.uk

References

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1. Ferlay, J, Soerjomataram, I, Ervik, M, et al. (2013) GLOBOCAN 2012 v1.0, Prostate Cancer: Estimated Incidence, Mortality and Prevalence Worldwide in 2012. Lyon, France: International Agency for Research on Cancer. http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx (accessed June 2018).
2. Cancer Research UK (2018) Prostate cancer statistics. http://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/prostate-cancer (accessed June 2018).
3. Bradbury, BD, Wilk, JB & Kaye, JA (2005) Obesity and the risk of prostate cancer (United States). Cancer Causes Control 16, 637641.
4. Rodriguez, C, Patel, AV, Calle, EE, et al. (2001) Body mass index, height, and prostate cancer mortality in two large cohorts of adult men in the United States. Cancer Epidemiol Biomarkers Prev 10, 345353.
5. Stroup, SP, Cullen, J, Auge, BK, et al. (2007) Effect of obesity on prostate-specific antigen recurrence after radiation therapy for localized prostate cancer as measured by the 2006 radiation therapy oncology group-American Society for Therapeutic Radiation and Oncology (RTOG-ASTRO) Phoenix consensus definition. Cancer 110, 10031009.
6. World Cancer Research Fund/American Institute for Cancer Research (2018) Continuous Update Project Expert Report. Diet, nutrition, physical activity, and prostate cancer. http://dietandcancerreport.org (accessed June 2018).
7. Markozannes, G, Tzoulaki, I, Karli, D, et al. (2016) Diet, body size, physical activity and risk of prostate cancer: an umbrella review of the evidence. Eur J Cancer 69, 6169.
8. Rodriguez, C, Freedland, SJ, Deka, A, et al. (2007) Body mass index, weight change, and risk of prostate cancer in the cancer prevention study II nutrition cohort. Cancer Epidemiol Biomarkers Prev 16, 6369.
9. Focht, CB, Lucas, AR, Grainger, E, et al. (2018) Effects of a group-mediated exercise and dietary intervention in the treatment of prostate cancer patients undergoing androgen deprivation therapy: results from the IDEA-P trial. Ann Behav Med 52, 412428.
10. Bourke, L, Doll, H, Crank, H, et al. (2011) Lifestyle intervention in men with advanced prostate cancer receiving androgen suppression therapy: a feasibility study. Cancer Epidemiol Biomarkers Prev 20, 647657.
11. Buffart, LM, Galvao, DA, Brug, J, et al. (2014) Evidence-based physical activity guidelines for cancer survivors: current guidelines, knowledge gaps and future research directions. Cancer Treat Rev 40, 327340.
12. Mohamad, H, McNeill, G, Haseen, F, et al. (2015) The effect of dietary and exercise interventions on body weight in prostate cancer patients: a systematic review. Nutr Cancer 67, 4360.
13. Hartmann-Boyce, J, Jebb, SA, Fletcher, R, et al. (2015) Self-help for weight loss in overweight and obese adults: systematic review and meta-analysis. Am J Publ Health 105, e43e57.
14. Demark-Wahnefried, W, Morey, MC, Sloane, R, et al. (2012) Reach Out to Enhance Wellness home-based diet-exercise intervention promotes reproducible and sustainable improvements in health behaviors, body weight and physical functioning on older overweight/obese cancer survivors. J Clin Oncol 30, 23542361.
15. Porter Starr, KN & Bales, CW (2015) Excessive body weight in older adults: concerns and recommendations. Clin Geriatr Med 3, 311326.
16. Satia, JA, Walsh, JF & Pruthi, RS (2009) Health behaviour changes in white and African American prostate cancer survivors. Cancer Nurs 32, 107117.
17. Aaronson, NK (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85, 365.
18. Fayers, P, Aaronson, NK, Bjordal, K, et al. (2001) EORTC QLQ-C30 Scoring Manual, 3rd ed. Brussels: European Organisation for Research and Treatment of Cancer.
19. Jolly, K, Lewis, A, Beach, J, et al. (2011) Comparison of range of commercial or primary care led weight reduction programmes with minimal intervention control for weight loss in obesity: lighten up randomised controlled trial. BMJ 343, d6500.
20. Hunt, K, Wyke, S, Gray, CM, et al. (2014) A gender-sensitised weight loss and healthy living programme for overweight and obese men delivered by Scottish Premier League football clubs (FFIT): a pragmatic randomised controlled trial. Lancet 383, 12111221.
21. Anderson, AS, Craigie, AM, Caswell, S, et al. (2014) The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme: randomised controlled trial. BMJ 348 , g1823.
22. Donachie, C, Wyke, S, Mutrie, N, et al. (2017) 'It’s like a personal motivator that you carried around wi’ you': utilising self-determination theory to understand men’s experiences of using pedometers to increase physical activity in a weight management programme. Int J Behav Nutr Phys Act 14, 61.
23. Demark-Wahnefried, W, Clipp, EC, Morey, MC, et al. (2006) Lifestyle intervention development study to improve physical function in older adults with cancer: outcomes from project LEAD. J Clin Oncol 24, 34653473.

Keywords

A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer: pilot study of the Prostate Cancer Weight Management (PRO-MAN) randomised controlled trial

  • H. Mohamad (a1), M. Ntessalen (a1), L. C. A. Craig (a1) (a2), J. Clark (a3), S. Fielding (a4), J. N’Dow (a5), S. D. Heys (a6) and G. McNeill (a1)...

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