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Post-moderate-intensity exercise energy replacement does not reduce subsequent appetite and energy intake in adolescents with obesity

  • D. Thivel (a1) (a2) (a3), J. Roche (a1), M. Miguet (a1), A. Fillon (a1) (a4), M. Khammassi (a1), K. Beaulieu (a3), G. Finlayson (a3), B. Pereira (a5), M. Miyashita (a6), A. E. Thackray (a7), J. Masurier (a4), M. Duclos (a2) (a8) (a9) (a10) and Y. Boirie (a2) (a8) (a10) (a11)...


Exercise modifies energy intake (EI) in adolescents with obesity, but whether this is mediated by the exercise-induced energy deficit remains unknown. The present study examined the effect of exercise with and without dietary replacement of the exercise energy expenditure on appetite, EI and food reward in adolescents with obesity. Fourteen 12–15-year-old adolescents with obesity (eight girls; Tanner 3–4; BMI 34·8 (sd 5·7) kg/m2; BMI z score 2·3 (sd 0·4)) randomly completed three experimental conditions: (i) rest control (CON); (ii) 30-min cycling (EX) and (iii) 30-min cycling with dietary energy replacement (EX + R). Ad libitum EI was assessed at lunch and dinner, and food reward (Leeds Food Preference Questionnaire) before and after lunch. Appetite was assessed at regular intervals. Lunch, evening and total EI (excluding the post-exercise snack in EX − R) were similar across conditions. Lunch and total EI including the post-exercise snack in EX + R were higher in EX − R than CON and EX; EX and CON were similar. Total relative EI was lower in EX (6284 (sd 2042) kJ) compared with CON (7167 (sd 2218) kJ; P < 0·05) and higher in EX + R (7736 (sd 2033) kJ) compared with CON (P < 0·001). Appetite and satiety quotients did not differ across conditions (P ≥ 0·10). Pre-meal explicit liking for fat was lower in EX compared with CON and EX + R (P = 0·05). There was time by condition interaction between EX and CON for explicit wanting and liking for fat (P = 0·01). Despite similar appetite and EI, adolescents with obesity do not adapt their post-exercise food intake to account for immediate dietary replacement of the exercise-induced energy deficit, favouring a short-term positive energy balance.


Corresponding author

*Corresponding author: D. Thivel, fax +33 4 73 40 76 79, email


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1.NCD Risk Factor Collaboration (NCD-RisC) (2017) Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet 390, 26272642.
2.Swinburn, BA, Sacks, G, Hall, KD, et al. (2011) The global obesity pandemic: shaped by global drivers and local environments. Lancet 378, 804814.
3.Donnelly, JE, Blair, SN, Jakicic, JM, et al. (2009) American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc 41, 459471.
4.Deighton, K & Stensel, DJ (2014) Creating an acute energy deficit without stimulating compensatory increases in appetite: is there an optimal exercise protocol? Proc Nutr Soc 73, 352358.
5.Schubert, MM, Desbrow, B, Sabapathy, S, et al. (2013) Acute exercise and subsequent energy intake. A meta-analysis. Appetite 63, 92104.
6.Thivel, D, Metz, L, Julien, A, et al. (2014) Obese but not lean adolescents spontaneously decrease energy intake after intensive exercise. Physiol Behav 123, 4146.
7.Fearnbach, SN, Silvert, L, Pereira, B, et al. (2017) Reduced neural responses to food cues might contribute to the anorexigenic effect of acute exercise observed in obese but not lean adolescents. Nutr Res 44, 7684.
8.Thivel, D, Rumbold, PL, King, NA, et al. (2016) Acute post-exercise energy and macronutrient intake in lean and obese youth: a systematic review and meta-analysis. Int J Obes 40, 14691479.
9.Thivel, D, Finlayson, G & Blundell, JE (2019) Homeostatic and neurocognitive control of energy intake in response to exercise in pediatric obesity: a psychobiological framework. Obes Rev 20, 316324.
10.Miguet, M, Fillon, A, Khammassi, M, et al. (2018) Appetite, energy intake and food reward responses to an acute High Intensity Interval Exercise in adolescents with obesity. Physiol Behav 195, 9097.
11.Tamam, S, Bellissimo, N, Patel, BP, et al. (2012) Overweight and obese boys reduce food intake in response to a glucose drink but fail to increase intake in response to exercise of short duration. Appl Physiol Nutr Metab 37, 520529.
12.Hunschede, S, Kubant, R, Akilen, R, et al. (2017) The role of IL-6 in appetite suppression after high-intensity exercise in normal-weight and obese boys. Curr Dev Nutr 1, e000398.
13.Varley-Campbell, JL, Moore, MS & Williams, CA (2017) The effects of a mid-morning snack and moderate-intensity exercise on acute appetite and energy intake in 12-14-year-old adolescents. Br J Nutr 117, 602610.
14.Thivel, D, Duché, P & Morio, B (2012) Discussion of “Overweight and obese boys reduce food intake in response to a glucose drink but fail to increase intake in response to exercise of short duration”. Appl Physiol Nutr Metab 37, 10141015; discussion 1016–1017.
15.Cole, TJ, Bellizzi, MC, Flegal, KM, et al. (2000) Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 320, 12401243.
16.Craig, CL, Marshall, AL, Sjostrom, M, et al. (2003) International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 35, 13811395.
17.Bryant, EJ, Thivel, D, Chaput, JP, et al. (2018) Development and validation of the Child Three-Factor Eating Questionnaire (CTFEQr17). Public Health Nutr 21, 25582567.
18.WHO Multicentre Growth Reference Study Group (2006) WHO child growth standards based on length/height, weight and age. Acta Paediatr Suppl 450, 7685.
19.Rowland, TW (1996) Developmental Exercise Physiology. Champaign, IL: Human Kinetics.
20.Murphy, SP & Poos, MI (2002) Dietary reference intakes: summary of applications in dietary assessment. Public Health Nutr 5, 843849.
21.Flint, A, Raben, A, Blundell, JE, et al. (2000) Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studies. Int J Obes Relat Metab Disord 24, 3848.
22.Drapeau, V, King, N, Hetherington, M, et al. (2007) Appetite sensations and satiety quotient: predictors of energy intake and weight loss. Appetite 48, 159166.
23.Dalton, M & Finlayson, G (2014) Psychobiological examination of liking and wanting for fat and sweet taste in trait binge eating females. Physiol Behav 136, 128134.
24.Eldridge, SM, Chan, CL, Campbell, MJ, et al. (2016) CONSORT 2010 statement: extension to randomised pilot and feasibility trials. Pilot Feasibility Stud 2, 64.
25.Cohen, J (1988) Statistical Power Analysis for the Behavioral Sciences, 2nd ed. Hillsdale, NJ: Lawrence Erlbaum.
26.Feise, RJ (2002) Do multiple outcome measures require p-value adjustment? BMC Med Res Methodol 2, 8.
27.Rothman, G (1998) Modern Epidemiology, 2nd ed. Philadelphia, PA: Lippincott-Raven Publishers.
28.Masurier, J, Mathieu, ME, Fearnbach, SN, et al. (2018) Effect of exercise duration on subsequent appetite and energy intake in obese adolescent girls. Int J Sport Nutr Exerc Metab 28, 593601.
29.Thivel, D, Doucet, E, Julian, V, et al. (2017) Nutritional compensation to exercise- vs. diet-induced acute energy deficit in adolescents with obesity. Physiol Behav 176, 159164.
30.Prado, WL, Balagopal, PB, Lofrano-Prado, MC, et al. (2015) Effect of aerobic exercise on hunger feelings and satiety regulating hormones in obese teenage girls. Pediatr Exerc Sci 26, 463469.
31.Thivel, D, Isacco, L, Montaurier, C, et al. (2012) The 24-h energy intake of obese adolescents is spontaneously reduced after intensive exercise: a randomized controlled trial in calorimetric chambers. PLOS ONE 7, e29840.
32.Albert, MH, Drapeau, V & Mathieu, ME (2015) Timing of moderate-to-vigorous exercise and its impact on subsequent energy intake in young males. Physiol Behav 151, 557562.
33.Thivel, D, Genin, PM, Mathieu, ME, et al. (2016) Reproducibility of an in-laboratory test meal to assess ad libitum energy intake in adolescents with obesity. Appetite 105, 129133.
34.Fearnbach, SN, Silvert, L, Keller, KL, et al. (2016) Reduced neural response to food cues following exercise is accompanied by decreased energy intake in obese adolescents. Int J Obes (Lond) 40, 7783.
35.Thivel, D & Chaput, JP (2014) Are post-exercise appetite sensations and energy intake coupled in children and adolescents? Sports Med 44, 735741.
36.Finlayson, G, Bryant, E, Blundell, JE, et al. (2009) Acute compensatory eating following exercise is associated with implicit hedonic wanting for food. Physiol Behav 97, 6267.
37.Farah, NM, Brunstrom, JM & Gill, JM (2012) Using a novel computer-based approach to assess the acute effects of exercise on appetite-related measures. Appetite 58, 196204.
38.McNeil, J, Cadieux, S, Finlayson, G, et al. (2015) The effects of a single bout of aerobic or resistance exercise on food reward. Appetite 84, 264270.


Post-moderate-intensity exercise energy replacement does not reduce subsequent appetite and energy intake in adolescents with obesity

  • D. Thivel (a1) (a2) (a3), J. Roche (a1), M. Miguet (a1), A. Fillon (a1) (a4), M. Khammassi (a1), K. Beaulieu (a3), G. Finlayson (a3), B. Pereira (a5), M. Miyashita (a6), A. E. Thackray (a7), J. Masurier (a4), M. Duclos (a2) (a8) (a9) (a10) and Y. Boirie (a2) (a8) (a10) (a11)...


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