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Phyto-oestrogen levels in foods: the design and construction of the VENUS database

Published online by Cambridge University Press:  26 October 2011

Mairead Kiely ,
Marian Faughnan ,
Kristiina Wähälä ,
Henny Brants  and
Angela Mulligan
Mairead Kiely*
Affiliation:
Nutritional Sciences, Department of Food Science, Food Technology and Nutrition, University College Cork, Ireland
Marian Faughnan
Affiliation:
School of Biomedical and Life Sciences, University of Surrey, Guildford GU2 7XH, UK
Kristiina Wähälä
Affiliation:
Department of Chemistry, Laboratory of Organic Chemistry, PO Box 55, FIN-00014, University of Helsinki, Finland
Henny Brants
Affiliation:
TNO Nutrition and Food Research, Department of Nutritional Epidemiology, PO Box 360, 3700 AJ Zeist, The Netherlands
Angela Mulligan
Affiliation:
Department of Public Health and Primary Care, University of Cambridge, and MRC Dunn Human Nutrition Unit, Cambridge CB2 2XY, UK
*
*Corresponding author: Dr M. Kiely, fax +353 21 4270244, email m.kiely@ucc.ie
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The objective of the Vegetal Estrogens in Nutrition and the Skeleton (VENUS) project was to evaluate existing data on dietary exposure to compounds with oestrogenic and anti-oestrogenic effects present in plant foods as constituents or contaminants, and to identify and disseminate in vitro and in vivo methodologies to analyse the effects of such compounds on bone. To permit the assessment of exposure to isoflavones in European populations (Italy, the UK, Ireland, The Netherlands), the VENUS database of phyto-oestrogen levels in foods was established. Data on the isoflavone (genistein and daidzein) content of 791 foods, including almost 300 foods commonly consumed in Europe, were collected. Levels of coumestrol, formononetin and biochanin A in a limited number of foods were also included. Lignan levels (secoisolariciresinol and matairesinol) in 158 foods were incorporated into the database, which also contains information on the references sourced for the compositional data, on the analytical methods used by each author and on the number of foods analysed in each reference. The VENUS database was constructed in Microsoft® Access 2000, which is widely available as part of Microsoft® Office Professional. This paper outlines the procedures used for the selection and evaluation of existing literature data for incorporation into the database. In addition, the design of the database is described, along with the data entry and quality control procedures used in its construction. Limitations of the data are discussed and guidelines for its use are provided.

Keywords

IsoflavonesFood composition dataLignans
Type
Research Article
Information
British Journal of Nutrition , Volume 89 , Issue S1: Effects of Phyto-oestrogens on Bone Health: the VENUS Concerted Action , June 2003 , pp. S19 - S23
Copyright
Copyright © The Nutrition Society 2003

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