Ambrosone, CB, Freudenheim, JL, Thompson, PA, Bowman, E, Vena, JE, Marshall, JR, Graham, S, Laughlin, R, Nemoto, T & Shields, PG (1999) Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res 59, 602–606.
Cai, Q, Shu, XO, Wen, W, Cheng, JR, Dai, Q, Gao, YT & Zheng, W (2004) Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: results from the Shanghai Breast Cancer Study. Breast Cancer Res 6, R647–R655.
Cardon, LR & Bell, JI (2001) Association study designs for complex diseases. Nat Rev Genet 2, 91–99.
Cashman, KD (2005) Homocysteine and osteoporotic fracture risk: a potential role for B vitamins. Nutr Rev 63, 29–36.
Colditz, GA, Willett, WC, Rotnitzky, A & Manson, JE (1995) Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 122, 481–486.
Cusack, S & Cashman, KD (2003) Impact of genetic variation on metabolic response of bone to diet. Proc Nutr Soc 62, 901–912.
Davis, CD & Milner, J (2004) Frontiers in nutrigenomics, proteomics, metabolomics and cancer prevention. Mutat Res 551, 51–64.
Deitz, AC, Zheng, W, Leff, MA, Gross, M, Wen, WQ, Doll, MA, Xiao, GH, Folsom, AR & Hein, DW (2000) N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women. Cancer Epidemiol Biomarkers Prev 9, 905–910.
Dolinoy, DC, Weidman, JR, Waterland, RA & Jirtle, RL (2006) Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 11, 567–572.
Enattah, NS, Sahi, T, Savilahti, E, Terwilliger, JD, Peltonen, L & Jarvela, I (2002) Identification of a variant associated with adult-type hypolactasia. Nat Genet 30, 233–237.
Feuk, L, Marshall, CR, Wintle, RF & Scherer, SW (2006) Structural variants: changing the landscape of chromosomes and design of disease studies. Hum Mol Genet 15 (Spec. No. 1), R57–R66.
German, JB, Bauman, DE, Burrin, DG, et al. (2004) Metabolomics in the opening decade of the 21st century: building the roads to individualized health. J Nutr 134, 2729–2732.
Helgadottir, A, Manolescu, A, Helgason, A, et al. (2006) A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genetics 38, 68–74.
Hesketh, J, Wybranska, J, Dommels, Y, King, M, Ellitot, R, Pico, C & Keijer, J (2006) Nutrient-gene interactions in benefit-risk analysis. Br J Nutr 95, 1232–1236.
Hinds, DA, Stuve, LL, Nilsen, GB, Halperin, E, Eskin, E, Ballinger, DG, Frazer, KA & Cox, DR (2005) Whole-genome patterns of common DNA variation in three human populations. Science 307, 1072–1079.
Hirschhorn, JN, Lohmueller, K, Byrne, E & Hirschhorn, K (2002) A comprehensive review of genetic association studies. Genet Med 4, 45–61.
Jaenisch, R & Bird, A (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genetics 33, Suppl., 245–254.
Joseph, MA, Moysich, KB, Freudenheim, JL, Shields, PG, Bowman, ED, Zhang, Y, Marshall, JR & Ambrosone, CB (2004) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk. Nutr Cancer 50, 206–213.
Kaput, J, Ordovas, JM, Ferguson, L, et al. (2005) The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr 94, 623–632.
Kaput, J & Rodriguez, RL (2004) Nutritional genomics: the next frontier in the postgenomic era. Physiol Genomics 16, 166–177.
Knoblauch, H, Bauerfeind, A, Toliat, MR, et al. (2004) Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum Mol Genet 13, 993–1004.
Levy, HL (1999) Phenylketonuria: old disease, new approach to treatment. Proc Natl Acad Sci U S A 96, 1811–1813.
Li, H, Kantoff, PW, Giovannucci, E, Leitzmann, MF, Gaziano, JM, Stampfer, MJ & Ma, J (2005) Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res 65, 2498–24504.
Loktionov, A, Scollen, S, McKeown, N & Bingham, SA (2000) Gene-nutrient interactions: dietary behaviour associated with high coronary heart disease risk particularly affects serum LDL cholesterol in apolipoprotein E epsilon4-carrying free-living individuals. Br J Nutr 84, 885–890.
Mathers, JC (2002) Pulses and carcinogenesis: potential for the prevention of colon, breast and other cancers. Br J Nutr 88, Suppl. 3, S273–S279.
Nishina, PM, Wang, J, Toyofuku, W, Kuypers, FA, Ishida, BY & Paigen, B (1993) Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids 28, 599–605.
Ordovas, JM (2004) The quest for cardiovascular health in the genomic era: nutrigenetics and plasma lipoproteins. Proc Nutr Soc 63, 145–152.
Ordovas, JM & Corella, D (2004) Nutritional genomics. Annu Rev Genomics Hum Genet 5, 71–118.
Ordovas, JM, Corella, D, Cupples, LA, Demissie, S, Kelleher, A, Coltell, O, Wilson, PW, Schaefer, EJ & Tucker, K (2002) Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. Am J Clin Nutr 75, 38–46.
Payseur, BA, Clark, AG, Hixson, J, Boerwinkle, E & Sing, CF (2006) Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. Genetic Epidemiol 30, 508–518.
Plum, L, Giesen, K, Kluge, R, Junger, E, Linnartz, K, Schürmann, A, Becker, W & Joost, HG (2002) Characterisation of the mouse diabetes susceptibility locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat. Diabetologia 45, 823–830.
Redon, R, Ishikawa, S, Fitch, KR, et al. (2006) Global variation in copy number in the human genome. Nature 444, 444–454.
Russo, G (2006) Home health tests are ‘genetic horoscopes’. Nature 442, 497.
Seow, A, Yuan, JM, Sun, CL, Van Den Berg, D, Lee, HP & Yu, MC (2002) Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 23, 2055–2061.
Sharp, L & Little, J (2004) Polymorphisms in folate metabolism and colorectal neoplasia: a HuGE review. Am J Epidemiol 159, 423–443.
Song, Y, Niu, T, Manson, JE, Kwiatkowski, DJ & Liu, S (2004) Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies. Am J Hum Genet 74, 208–222.
Strain, JJ, Dowey, L, Ward, M, Pentieva, K & McNulty, H (2004) B-vitamins, homocysteine metabolism and CVD. Proc Nutr Soc 63, 597–603.
van Ommen, B & Stierum, R (2002) Nutrigenomics: exploiting systems biology in the nutrition and health arena. Curr Opin Biotechnol 13, 517–521.
Wuschke, S, Dahm, S, Schmidt, C, Joost, HG & Al-Hasani, H (2006) A meta-analysis of QTL associated with body weight and adiposity in mice. Int J Obesity .