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Pattern of gastric emptying in the pig: Relation to feeding

  • P. C. Gregory (a1), M. Mcfadyen (a1) and D. V. Rayner (a1)

Abstract

The aims of the present study were to compare the gastric emptying of dry matter (DM) and liquids during the feeding period with that following meal consumption, to clarify the relationship between feeding and gastric emptying, and to investigate how gastric emptying changes in growing animals. The studies were performed in pigs fitted with a gastric cannula and fed on a normal finely ground solid diet mixed with water containing CrEDTA as liquid marker. Gastric emptying was measured using a gastric evacuation technique. It was observed that between 0.75 and 6 h after feeding the total amounts emptied increased, but the proportion of the meal emptied fell, with increase in meal size; emptying of both DM and liquids with large and small meals followed and exponential pattern. In contrast, while the animals were feeding, there was linear and rapid emptying of both DM and liquids following a very short (approximately 2 min) lag phase before emptying began. The rate of emptying increased linearly with body-;weight (by 0.55 g DM/min and by 0.24 ml/min per kg body-weight over the range 58–200 kg) such that the emptying of digestible energy per kg metabolic body-weight (W0.75) was roughly maintained (between 2.9 and 3.2 kJ/min per kg W0.75). This suggests that the rate of emptying may be linked in some way with the metabolic requirements of the body. The biphasic pattern of gastric emptying observed is probably the intrinsic pattern of emptying of a meal which does not require breakdown of particles before emptying can occur.

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References

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Ash, R. W. (1962). Gastro-intestinal re-entrant cannulae for studies of digestion in sheep. Animal Production 4, 309312.
Binnerts, W. T., Van't Klooster, A. T. & Frens, A. M. (1968). Soluble chromium indicator measured by atomic absorption in digestion experiments. Veterinary Record 82, 470.
Brener, W., Hendrix, T. R. & McHugh, P. R. (1983). Regulation of the gastric emptying of glucose. Gastroenterology 85, 7682.
Camilleri, M., Malagelada, J. R., Brown, M. L., Becker, G. & Zinsmeister, A. R. (1985). Relation between antral motility and gastric emptying of solids and liquids in humans. American Journal of Physiology 249, G580G585.
Christian, R. R. & Coup, M. R. (1954). Measurement of feed intake by grazing cattle and sheep. VI. The determination of chromic oxide in faeces. New Zealand Journal of Science and Technology 36A, 328330.
Cuber, J. C. & Laplace, J. P. (1979). Evacuation gastrique de l'amidon et de l'azote d'un régime semi-purifié à base d'amidon de mais chez le Pore. Annales de Zootechnie 28, 173184.
Cuber, J. C., Laplace, J. P. & Villiers, P. A. (1980). Fistulation de l'estomac et contenus gastriques résiduals après ingestion d'un régime semi-purifié à bas d'amidon de mais chez le pore. Reproduction, Nutrition, Developpement 20, 11611172.
Elashoff, J. D., Reedy, T. J. & Meyer, J. H. (1982). Analysis of gastric emptying data. Gastroenterology 83, 13061312.
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1987). The influence of gastrointestinal infusions of glucose on regulation of food intake in pigs. Quarterly Journal of Experimental Physiology 72, 525535.
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1988). Regulation of stomach emptying in pigs. Journal of Physiology 396, 18P.
Gregory, P. C., McFadyen, M. & Rayner, D. V. (1989). Control of gastric emptying in the pig: influence of duodenal infusions of glucose and emulsified fat. Quarterly Journal of Experimental Physiology 74, 109119.
Gregory, P. C., Miller, S. J. & Brewer, A. C. (1985). The relation between food intake and abomasal emptying and small intestinal transit time in sheep. British Journal of Nutrition 53, 373380.
Gregory, P. C. & Rayner, D. V. (1985). Stomach emptying of solids in the pig: relation to feeding. Digestive Diseases and Sciences 30, 771.
Gregory, P. C. & Rayner, D. V. (1986). The role of stomach emptying in short-term control of food intake in pigs. Journal of Physiology 378, 25P.
Gregory, P. C. & Rayner, D. V. (1987). The influence of gastrointestinal infusion of fats on regulation of food intake in pigs. Journal of Physiology 385, 471481.
Hinder, R. A. & Kelly, K. A. (1977). Canine gastric emptying of solids and liquids. American Journal of Physiology 233, E335E340.
Horowitz, M., Collins, P. J. & Shearman, D. J. C. (1986). Effect of increasing the caloric/osmotic content of the liquid component of a mixed solid and liquid meal on gastric emptying in obese subjects. Human Nutrition: Clinical Nutrition 40 C, 5156.
Hunt, J. N. (1980). A possible relation between the regulation of gastric emptying and food intake. American Journal of Physiology 239, G1G4.
Hunt, J. N. & Spurrell, N. R. (1951). The pattern of emptying of the human stomach. Journal of Physiology 113, 157168.
Hunt, J. N. & Stubbs, D. F. (1975). The volume and energy content of meals as determinants of gastric emptying. Journal of Physiology 245, 209225.
Johansson, C. & Eklund, K. (1976). Relation between body weight and gastric and intestinal handling of an oral caloric load. Gut 17, 456462.
Kalogeris, T. J., Reidelberger, R. D. & Mendel, V. E. (1983). Effect of nutrient density and composition of liquid meals on gastric emptying in feeding rats. American Journal of Physiology 244, R865R871.
Kleiber, M. (1947). Bodysize and metabolic rate. Physiology Reviews 27, 511541.
Laplace, J. P., Pons, O., Cuber, J. C., Kabore, C. & Villiers, P. A. (1981). Effects de la nature de l'amidon (blé ou mais) et des proteines (poisson ou gluten) sur les facteurs de contrôle et le décours de l'évacuation gastrique d'un régime semi-purifié chez le porc. Applications de l'analyse multidimensionelle et de la régression polynomiale. Annales de Zootechnie 30, 209248.
Laplace, J. P. & Tomassone, R. (1970). Evacuation gastro-duodénale chez le pore. Annales de Zootechnie 19, 303332.
Lavigne, M. E., Wiley, Z. D., Meyer, J. H., Martin, P. & MacGregor, I. L. (1978). Gastric emptying rates of solid foods in relation to body size. Gastroenterology 74, 12581260.
Low, A. G., Pittman, R. J. & Elliott, R. J. (1985). Gastric emptying of barley-soya-bean diets in the pig: effects of feeding level, supplementary maize oil, sucrose or cellulose and water intake. British Journal of Nutrition 54, 437447.
McCann, M. J. & Stricker, E. M. (1986). Gastric emptying of glucose loads in rats: effects of insulin-induced hypoglycemia. American Journal of Physiology 251, R609R613.
McHugh, P. R. & Moran, T. H. (1979). Calories and gastric emptying: A regulatory capacity with implications for feeding. American Journal of Physiology 236, R254R260.
McHugh, P. R., Moran, T. H. & Barton, G. N. (1975). Satiety: A graded behavioral phenomenon regulating calorie intake. Science 190, 167169.
McHugh, P. R., Moran, T. H. & Wirth, J. B. (1982). Postpyloric regulation of gastric emptying in rhesus monkeys. American Journal of Physiology 243, R408R415.
Malagelada, J. R., Go, V. L. W. & Summerskill, W. H. J. (1979). Different gastric, pancreatic and biliary responses to solid-liquid or homogenized meals. Digestive Diseases and Sciences 24, 101109.
Meyer, J. H., Dressman, J., Fink., A. & Amidon, G. (1985). Effect of size and density on canine gastric emptying of nondigestible solids. Gastroenterology 89, 805813.
Meyer, J. H., Ohashi, H., Jehn, D. & Thomson, J. B. (1981). Size of liver particles emptied from the human stomach. Gastroenterology 80, 489496.
Meyer, J. H., Thomson, J. B., Cohen, M. B., Shadchehr, A. & Mandiola, S. A. (1979). Sieving of solid food by the canine stomach and sieving after gastric surgery. Gastroenterology 76, 804813.
Moore, J. G., Christian, P. E., Brown, J. A., Brophy, C., Datz, F., Taylor, A. & Alazraki, N. (1984). Influence of meal weight and caloric content on gastric emptying of meals in man. Digestive Diseases and Sciences 29, 513519.
Rayner, D. V. & Gregory, P. C. (1989). The role of the gastrointestinal tract in the control of voluntary food intake. In The Voluntary Food Intake of Pigs. Occasional Publication no. 13, British Society of Animal Production, pp. 2739 [Forbes, J. M., Varley, M. A. and Lawrence, T. L. J., editors]. Milton Keynes: British Society of Animal Production.
Reed, J. H. & Kidder, D. E. (1972). The effect of glucose, galactose and sorbitol on gastric emptying in the young pig. Quarterly Journal of Experimental Physiology 57, 3036.
Rosenthal, S. & Nasset, E. S. (1958). Gastric emptying and intestinal absorption of carbohydrate and protein as influenced by the nature of the meal. Journal of Nutrition 66, 91103.
Setler, P. E. & Smith, G. P. (1969). Gastric emptying in rats with chronic gastric fistulas. American Journal of Digestive Diseases 14, 137142.
Tan, T. N., Weston, R. H. & Hogan, J. P. (1971). Use of 103Ru-labelled tris (1,10-phenanth ruthenium(11)) chloride as a marker in digestion studies in sheep. International Journal of Applied Radiation and Isotopes 22, 301308.
Uden, P., Colucci, P. E. & Van Soest, P. (1980). Investigation of chromium, cerium and cobalt, as markers in digesta – rate of passage studies. Journal of Science of Food and Agriculture 31, 625632.
Wright, R. A., Krinsky, S., Fleeman, C., Trujillo, J. & Teague, E. (1983). Gastric emptying and obesity. Gastroenterology 84, 747751.

Keywords

Pattern of gastric emptying in the pig: Relation to feeding

  • P. C. Gregory (a1), M. Mcfadyen (a1) and D. V. Rayner (a1)

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