Skip to main content Accessibility help
×
Home

Influence of folic acid supplements on the carry-over of folates from the sow to the piglet

  • B. Barkow (a1), J. J. Matte (a2), H. Böhme (a1) and G. Flachowsky (a1)

Abstract

This experiment aimed to investigate the influence of folic acid supplements on the carry-over of folates from the sow to the fetus during late gestation and to the suckling piglet. Two groups of sixteen German Landrace sows received, during gestation and lactation, a diet supplemented with either 0 or 10 mg folic acid/kg. Increased folic acid concentrations in the serum of sows were detected only at the end of gestation (day 100) and at the end of lactation (day 28). The supplementation with folic acid to the sows' diet improved the folic acid supply of the fetus compared with unsupplemented controls; values were respectively 92.6 v. 56.2 nmol folates/l serum in newborn piglets and 171.9 v. 76.3 μmol folates/g fresh liver in stillborn piglets (P < 0.05). Folate concentrations in colostrum and milk (day 28) were 3.6- and 5.0-times higher in supplemented than unsupplemented sows. This treatment effect was also reflected in the serum of piglets until weaning. Therefore, the folic acid supply for the suckling piglet is dependent mainly upon the carry-over of maternal folates via colostrum and milk.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Influence of folic acid supplements on the carry-over of folates from the sow to the piglet
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Influence of folic acid supplements on the carry-over of folates from the sow to the piglet
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Influence of folic acid supplements on the carry-over of folates from the sow to the piglet
      Available formats
      ×

Copyright

Corresponding author

*Corresponding author: Professor G. F;achowsky fax +49 531 596 376 email: herweg@te.fal.de

References

Hide All
Bässler, K.H. (1997) Vitamin-lexicon for physicians, pharmacrits and nutritionists. 2nd ed., Frankfurt (Main): Govi-Verlag, pp. 104136.
Cerna, J & Kas, J (1983) New conception of folacin assay in starch or glycogen containing food samples Nahrung 27, 957964.
Dumoulin, PG, Girard, CL, Matte, JJ & St-Laurent, GJ (1991) Effects of parenteral supplement of folic acid and its interaction with level of feed intake on hepatic tissues and growth performance of young dairy heifers. Journal of Animal Science 69, 16571666.
Duquette, J, Matte, JJ, Farmer, C, Girard, CL & Laforest, J-P (1997) Pre- and post-mating dietary supplements of folic acid and uterin secretory activity in gilts. Canadian Journal of Animal Science 77, 415420.
Ek, J & Magnus, EM (1981) Plasma, red blood cell folate during normal pregnancies. Acta Obstetricia et Gynaecologica Scandinavica 60, 247251.
Fuchs, B, Orda, J & Wilieczkiewicz, A (1996) Effect of folic acid supplementation in pregnant sows on the fetal mortality. Medycyna Weterynarya Warschau 52, 293298.
German Society of Nutrition Physiology (1987) Energy and nutrient requirements. of domestic animals. Vol. 4, Pigs 4. Frankfurt (Main): DLG-Verlag.
Giguere, et al. (1999) Folic acid, uterus conditioning and control of the reproductive performance of nulliparous sows. Journées de la Recherche Procine en France 31, 33-38.
Girard, CL & Matte, JJ (1989) Serum folates in gestating and lactating dairy cows. Journal of Dairy Science 72, 32403246.
Girard, CL, Castonguay, F, Fahmy, MH & Matte, JJ (1996) Serum and milk folates during the first two gestations and laktations in Romanov, Finnsheep, and Suffolk ewes Journal of Animal Science 74, 17111715.
Harper, AF, Lindemann, MD, Chiba, LI, Combs, GE, Handlin, DL, Kornegay, ET & Southern, LL (1994) An assessment of dietary folic acid levels during gestation and lactation on reproductive and lactational performance of sows A cooperative study. Journal of Animal Science 72, 23382344.
Lynch, PB & Sheehy, PJA (1994) Response of breeding sows to long-term dietary supplementation with folic acid. Animal Production 58, 466.
Matte, JJ, Farmer, C, Girard, CL & Laforest, J-P (1996) Dietary folic acid, uterine function and early embryonic development in sows. Canadian Journal of Animal Science 76, 427433.
Matte, JJ & Girard, CL (1989) Effects of intramuscular injections of folic acid during lactation on folates in serum and milk and performance of sows and piglets. Journal of Animal Science 67, 426431.
Matte, JJ & Girard, CL (1999) An estimation of the requirement for folic acid in the gestating sow: The metabolism utilization of folates as a criterion of measurement. Journal of Animal Science 77, 159165.
Matte, JJ, Girard, CL & Brisson, GJ (1990) The effect of supplementary folic acid in gestation diets on folates status and reproductive performances of first parity sows. Journal of Animal Science 68, 370.
Matte, JJ, Girard, CL & Brisson, GJ (1984) Serum folates during the reproductive cycle of sows. Journal of Animal Science 59, 158163.
Matte, JJ, Girard, CL & Brisson, GJ (1992) The role of folic acid in the nutrition of gestating and lactating primiparous sows. Livestock Production Science 32, 131148.
Matte, JJ, Girard, CL & Tremblay, GF (1993) Effect of long-term addition of folic acid on folate status, growth performance, puberty attainment, and reproductive capacity of sows. Journal of Animal Science 71, 151157.
National Research Council (1998) Nutrient requirements of swine. 10th, Washington, DC: National Academy Press.
Natsuhori, M, Shimoda, M & Kokue, E (1996) Alterations of plasma folates in gestating sows and newborn piglets. American Journal of Physiology 270, R99-R104.
O'Connor, DL & Picciano, MF (1993) Plasma folate binding capacity of the reproducing pig. Journal of Nutritional Biochemistry 4, 482487.
O'Connor, DL, Picciano, MF, Roos, MA & Easter, RA (1989) Iron and folate utilization in reproducing swine and their progeny. Journal of Nutrition 119, 19841991.
O'Connor, DL, Tamura, T & Picciano, MF (1991) Pteroylpolyglutamates in human milk. American Journal of Clinical Nutrition 53, 930934.
Rothenberg, SP, da Costa, M, Lawson, J & Rosenberg, Z (1974) The determination of erythrocyte folate concentration using a two-phase ligand-binding radioassay. Blood 43, 437443.
Selhub, J, Arnold, R, Smith, AM & Picciano, MF (1984) Milk folate protein (FBP) A secretory protein for folate. Nutrition Research 4, 181187.
German Society of Nutrition Physiology (1987) Energy and nutrient requirements of domestic animals. Vol. 4, Pigs 4. Frankfurt (Main): DLG-Verlag.
Tamura, T, Yoshimura, Y & Arakawa, T (1980) Human milk folate and folate status in lactating mothers and their infants. American Journal of Clinical Nutrition 33, 193197.
Thaler, RC, Nelssen, JL, Goodband, RD & Alle, GL (1989) Effect of dietary folic acid supplementation on sow performance through two parities. Journal of Animal Science 67, 33603369.
Thenen, SW (1991) Gestational, and neonatal folate deficieny in rats Nutrition Research 11, 105116.
Tremblay, GF, Matte, JJ, Girard, CL & Brisson, GJ (1989) Serum zinc, iron and copper status during early gestation in sows fed a folic acid-supplemented diet. Journal of Animal Science 67, 733737.
Tremblay, GF, Matte, JJ, Lemieux, L & Brisson, GJ (1986) Serum folates in gestating swine after folic acid addition to diet. Journal of Animal Science 63, 11731178.

Keywords

Related content

Powered by UNSILO

Influence of folic acid supplements on the carry-over of folates from the sow to the piglet

  • B. Barkow (a1), J. J. Matte (a2), H. Böhme (a1) and G. Flachowsky (a1)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.