Hostname: page-component-848d4c4894-jbqgn Total loading time: 0 Render date: 2024-06-23T20:08:35.869Z Has data issue: false hasContentIssue false
  • English
  • Français

Influence of feeding level and of protein level in early life on the cellularity of adipose tissue and body fat content of growing pigs

Published online by Cambridge University Press:  09 March 2007

R. G. Campbell  and
A. C. Dunkin
R. G. Campbell*
Affiliation:
School of Agriculture and Forestry, University of Melbourne, Parkville, Victoria, 3052, Australia
A. C. Dunkin
Affiliation:
School of Agriculture and Forestry, University of Melbourne, Parkville, Victoria, 3052, Australia
*
Present address: Animal Research Institute, Princes Highway, Werribee, Victoria, 3030, Australia.
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The effects of level of feeding and level of protein in the early postnatal period on the cellularity of subcutaneous adipose tissue and body fat content of pigs were investigated in two experiments.

2. In Expt 1, piglets were given a common liquid diet at energy intakes equivalent to 2·8 or 5·2 times energy for maintenance (M) between 1·8 and 6·5 kg live weight (LW), and a common dry diet at 2·8 or 4·5 M between 6·5 and 20 kg LW. Between 20 and 75 kg LW all pigs were given a second dry diet at 4·0 M.

3. In both experiments the effects of nutritional treatments on fat cell number at 20 and 75 kg LW (Expt 1) and at 45 kg LW (Expt 2) were assessed by measuring the DNA content of the subcutaneous adipose tissue contained in the left shoulder joint. Fat cell size was assessed in the same tissue by measuring the diameter of collagenase-released adipocytes.

4. In Expt 1, raising the level of feeding between 1·8 and 6·5 kg LW increased body fat content and average fat cell diameter at both 6·5 (P < 0·01) and 20 kg LW (P < 0·05) but had no effect on either measurement at 75 kg LW. Similarly, raising the level of feeding between 6·5 and 20 kg LW increased body fat content and fat cell size at both 20 (P < 0·01) and 75 kg LW (P < 0·05). There was an almost twofold increase in the DNA content of subcutaneous adipose tisuue between 20 and 75 kg LW. However, it was not significantly affected at either weight by level of feeding before or subsequent to 6·5 kg LW.

5. In Expt 2, reducing the level of dietary protein between 1·8 and 6·5 kg LW increased body fat content (P < 0·01) and fat cell size (P < 0·01) at the latter weight. Although level of dietary protein to 6·5 kg LW had no effect on body fat content or the weight of subcutaneous adipose tissue in the shoulder joint at 45 kg LW, pigs given the lowest-protein diet contained less DNA (P < 0·05) in the subcutaneous adipose tissue and had larger (P < 0·05) fat cells than those given the highest-protein diet to 6·5 kg LW. Reducing the protein content of the diet fed subsequent to 6·5 kg LW increased the body fat content (P < 0·01) and fat cell size (P < 0·01) at 45 kg LW.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 49 , Issue 1 , January 1983 , pp. 109 - 118
Copyright
Copyright © The Nutrition Society 1983

References

Agricultural Research Council (1967). Nutrient Requirements of Farm Livestock, No. 3, Pigs. London: Agricultural Research Council.Google Scholar
Bertrand, H. A. & Masoro, E. J. (1977). Nature, Lond. 266, 62.CrossRefGoogle Scholar
Black, J. L. (1974). Proc. Aust. Soc. Anim. Prod. 10, 211.Google Scholar
Braude, R. & Newport, M. J. (1973). Br. J. Nutr. 29, 447.CrossRefGoogle Scholar
Brook, C. G. D. (1972). Lancet ii, 624.CrossRefGoogle Scholar
Campbell, R. G. (1981). The influence of nutrition in early life on growth and development in the pig. PhD Thesis, Melbourne University.Google Scholar
Campbell, R. G. & Dunkin, A. C. (1980). Proc. Nutr. Soc. Aust. 5, 156.Google Scholar
Duncan, D. B. (1955). Biometrics 11, 1.CrossRefGoogle Scholar
Gurr, M. I. & Kirtland, J. (1978). Int. J. Obesity. 2, 401.Google Scholar
Hirsch, J. & Knittle, J. L. (1970). Fedn. Proc. Fedn. Am. Socs. exp. Biol. 29, 1516.Google Scholar
Hood, R. L. (1977). Proc. Nutr. Soc. Aust. 2, 43.Google Scholar
Hood, R. L. & Allen, R. E. (1977). J. Lipid Res. 18, 275.CrossRefGoogle Scholar
Kirtland, J. & Gurr, M. I. (1980). J. agric. Sci., Camb. 95, 325.CrossRefGoogle Scholar
Knittle, J. L. (1972). J. Nutr. 102, 427.CrossRefGoogle Scholar
Knittle, J. L. & Hirsch, J. (1968). J. clin. Invest. 47, 2091.CrossRefGoogle Scholar
Lee, Y. B., Kauffman, R. G. & Grummer, R. H. (1973a). J. Anim. Sci. 37, 1312.CrossRefGoogle Scholar
Lee, Y. B., Kauffman, R. G. & Grummer, R. H. (1973b). J. Anim. Sci. 37, 1319.CrossRefGoogle Scholar
Martin, R. F. & Donohue, D. C. (1972). Analyt. Biochem. 47, 562.CrossRefGoogle Scholar
Moss, F. P. (1968). Am. J. Anat. 122, 555.CrossRefGoogle Scholar
Oscai, L. B., Biblrak, S. P., Dubach, F. B., McGarr, J. A. & Spirakis, C. N. (1974). Am. J. Physiol. 227, 91.CrossRefGoogle Scholar
Oscai, L. B., Spirakis, C. N. & Wolff, C. A. (1972). J. Lipid Res. 13, 588.CrossRefGoogle Scholar
Salans, L. B., Knittle, J. L. & Hirsch, J. (1968). J. clin. Invest. 47, 153.CrossRefGoogle Scholar
Smith, U., Sjostrom, L. & Bjorntorp, P. (1972). J. Lipid Res. 13, 822.CrossRefGoogle Scholar
Williams, I. H. (1976). Nutrition of the young pig in relation to body composition. PhD Thesis, University of Melbourne.Google Scholar
Winick, M. & Noble, A. (1967). J. Nutr. 91, 179.CrossRefGoogle Scholar
Wood, J. D., Enser, M. B. & Restall, D. J. (1978). Anim. Prod. 27, 1.Google Scholar