Anderson, JW (2003) Diet first, then medication for hypercholesterolemia. JAMA 290, 531–533.
Anderson, JW, Johnstone, BM & Cook-Newell, ME (1995) Meta-analysis of soy protein intake on serum lipids. N Engl J Med 333, 276–282.
Bakhit, RM, Klein, BP, Essex-Sorlie, D, Ham, JO, Erdman, JW Jr & Potter, SM (1994) Intake of 25 g of soybean protein with or without soybean fiber alters plasma lipids in men with elevated cholesterol concentrations. J Nutr 124, 213–222.
Baum, JA, Teng, H, Erdman, JW Jr, et al. (1998) Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density-lipoprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women. Am J Clin Nutr 68, 545–551.
Blum, A, Lang, N, Vigder, F, Israeli, P, Gumanovsky, M, Lupovitz, S, Elgazi, A, Peleg, A & Ben-Ami, M (2003) Effects of soy protein on endothelium-dependent vasodilatation and lipid profile in postmenopausal women with mild hypercholesterolemia. Clin Invest Med 26, 20–26.
Brown, MS & Goldstein, JL (2004) Lowering plasma cholesterol by raising LDL receptors. Atheroscler Suppl 3, 57–59.
Carroll, KK (1982) Hypercholesterolemia and atherosclerosis: effects of dietary protein. Fed Proc 41, 2792–2796.
Chen, ST, Chen, JR, Yang, CS, Peng, SJ & Ferng, SH (2006) Effect of soya protein on serum lipid profile and lipoprotein concentrations in patients undergoing hypercholesterolaemic haemodialysis. Br J Nutr 95, 366–371.
Chen, ST, Ferng, SH, Yang, CS, Peng, SJ, Lee, HR & Chen, JR (2005) Variable effects of soy protein on plasma lipids in hyperlipidemic and normolipidemic hemodialysis patients. Am J Kidney Dis 46, 1099–1106.
Crouse, JR 3rd, Morgan, T, Terry, JG, Ellis, J, Vitolins, M & Burke, GL (1999) A randomized trial comparing the effect of casein with that of soy protein containing varying amounts of isoflavones on plasma concentrations of lipids and lipoproteins. Arch Intern Med 159, 2070–2076.
Cuevas, AM, Irribarra, VL, Castillo, OA, Yanez, MD & Germain, AM (2003) Isolated soy protein improves endothelial function in postmenopausal hypercholesterolemic women. Eur J Clin Nutr 57, 889–894.
Dalais, FS, Ebeling, PR, Kotsopoulos, D, McGrath, BP & Teede, HJ (2003) The effects of soy protein containing isoflavones on lipids and indices of bone resorption in postmenopausal women. Clin Endocrinol 58, 704–709.
Dent, SB, Peterson, CT, Brace, LD, Swain, JH, Reddy, MB, Hanson, KB, Robinson, JG & Alekel, DL (2001) Soy protein intake by perimenopausal women does not affect circulating lipids and lipoproteins or coagulation and fibrinolytic factors. J Nutr 131, 2280–2287.
Descovich, GC, Ceredi, C, Gaddi, A, et al. (1980) Multicenter study of soybean protein diet for outpatient hypercholesterolaemic patients. Lancet ii, 709–712.
Duranti, M, Lovati, MR, Dani, V, Barbiroli, A, Scarafoni, A, Castiglioni, S, Ponzone, C & Morazzoni, P (2004) The alpha' subunit from soybean 7S globulin lowers plasma lipids and upregulates liver beta-VLDL receptors in rats fed a hypercholesterolemic diet. J Nutr 134, 1334–1339.
Franceschini, G, Busnach, G, Vaccarino, V, Calabresi, L, Gianfranceschi, G & Sirtori, CR (1988) Apheretic treatment of severe familial hypercholesterolemia: comparison of dextran sulfate cellulose and double membrane filtration methods for low density lipoprotein removal. Atherosclerosis 73, 197–202.
Gaddi, A, Ciarrocchi, A, Matteucci, A, Rimondi, S, Ravaglia, G, Descovich, GC & Sirtori, CR (1991) Dietary treatment for familial hypercholesterolemia – differential effects of dietary soy protein according to the apolipoprotein E phenotypes. Am J Clin Nutr 53, 1191–1196.
Gaddi, A, Descovich, GC, Noseda, G, Fragiacomo, C, Nicolini, A, Montanari, G, Vanetti, G, Sirtori, M, Gatti, E & Sirtori, CR (1987) Hypercholesterolaemia treated by soybean protein diet. Arch Dis Child 62, 274–278.
Gardner, CD, Newell, KA, Cherin, R & Haskell, WL (2001) The effect of soy protein with or without isoflavones relative to milk protein on plasma lipids in hypercholesterolemic postmenopausal women. Am J Clin Nutr 73, 728–735.
Hall, WL, Vafeiadou, K, Hallund, J, et al. (2006) Soy-isoflavone-enriched foods and markers of lipid and glucose metabolism in postmenopausal women: interactions with genotype and equol production. Am J Clin Nutr 83, 592–600.
Hermansen, K, Hansen, B, Jacobsen, R, Clausen, P, Dalgaard, M, Dinesen, B, Holst, JJ, Pedersen, E & Astrup, A (2005) Effects of soy supplementation on blood lipids and arterial function in hypercholesterolaemic subjects. Eur J Clin Nutr 59, 843–850.
Hermansen, K, Sondergaard, M, Hoie, L, Carstensen, M & Brock, B (2001) Beneficial effects of a soy-based dietary supplement on lipid levels and cardiovascular risk markers in type 2 diabetic subjects. Diabetes Care 24, 228–233.
Jenkins, DJ, Kendall, CW, Jackson, CJ, Connelly, PW, Parker, T, Faulkner, D, Vidgen, E, Cunnane, SC, Leiter, LA & Josse, RG (2002) Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemic men and women. Am J Clin Nutr 76, 365–372.
Jenkins, DJ, Kendall, CW, Vidgen, E, et al. (2000) Effect of soy-based breakfast cereal on blood lipids and oxidized low-density lipoprotein. Metabolism 49, 1496–1500.
Keys, A (1967) Blood lipids in man. A brief review. J Am Dietet Assoc 51, 508–516.
Keys, A, Anderson, JT & Grande, F (1965 a) Serum cholesterol response in the diet. I. Iodine value of dietary fat versus 2S-P. Metabolism 14, 747–758.
Keys, A, Anderson, JT & Grande, F (1965 b) Serum cholesterol response in the diet. II. The effect of cholesterol in the diet. Metabolism 14, 759–765.
Kreijkamp-Kaspers, S, Kok, L, Grobbee, DE, de Haan, EH, Aleman, A, Lampe, JW & van der Schouw, YT (2004) Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 292, 65–74.
Levy, RI, Fredrickson, DS, Stone, NJ, et al. (1973) Cholestyramine in type II hyperlipoproteinemia. A double-blind trial. Ann Intern Med 79, 51–58.
Lichtenstein, AH, Jalbert, SM, Adlercreutz, H, Goldin, BR, Rasmussen, H, Schaefer, EJ & Ausman, LM (2002) Lipoprotein response to diets high in soy or animal protein with and without isoflavones in moderately hypercholesterolemic subjects. Arterioscler Thromb Vasc Biol 22, 1852–1858.
Lovati, MR, C. Manzoni, C, Canavesi, A, Sirtori, M, Vaccarino, V, Marchi, M, Gaddi, G & Sirtori, CR (1987) Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterolemic patients. J Clin Invest 80, 1498–1502.
Meinertz, H, Nilausen, K & Hilden, J (2002) Alcohol-extracted, but not intact, dietary soy protein lowers lipoprotein(a) markedly. Arterioscler Thromb Vasc Biol 22, 312–316.
Puska, P, Korpelainen, V, Hoie, LH, Skovlund, E, Lahti, T & Smerud, KT (2002) Soy in hypercholesterolaemia: a double-blind, placebo-controlled trial. Eur J Clin Nutr 56, 352–357.
Sacks, FM, Lichtenstein, A, Van Horn, L, Harris, W, Kris-Etherton, P & Winston, M; (2006) Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee. Circulation 113, 1034–1044.
Sirtori, CR, Agradi, E, Conti, F, Mantero, O & Gatti, E (1977) Soybean-protein diet in the treatment of type II hyperlipoproteinaemia. Lancet i, 275–277.
Sirtori, CR, Arnoldi, A & Johnson, SK (2005) Phytoestrogens: end of a tale. Ann Med 37, 423–438.
Sirtori, CR, Bosisio, R, Pazzucconi, F, Bondioli, A, Gatti, E, Lovati, MR & Murphy, P (2002) Soy milk with a high glycitein content does not reduce low-density lipoprotein cholesterolemia in type II hypercholesterolemic patients. Ann Nutr Metab 46, 88–92.
Sirtori, CR, Gatti, E, Mantero, O, Conti, F, Agradi, E, Tremoli, E, Sirtori, M, Fraterrigo, L, Tavazzi, L & Kritchevsky, D (1979) Clinical experience with the soybean protein diet in the treatment of hypercholesterolemia. Am J Clin Nutr 32, 1645–1658.
Sirtori, CR, Gianazza, E, Manzoni, C, Lovati, MR & Murphy, PA (1997) Role of isoflavones in the cholesterol reduction by soy proteins in the clinic. Am J Clin Nutr 65, 166–167.
Sirtori, CR, Lovati, MR, Gianazza, E, Bondioli, A, Staels, B & Auwerx, J (1998) Reduction of serum cholesterol by soy proteins: clinical experience and potential molecular mechanisms. Nutr Metab Cardiov Dis 8, 334–340.
Sirtori, CR, Pazzucconi, F, Colombo, F, Battistin, P, Bondioli, A & Descheemaeker, K (1999) Double-blind study of the addition of high-protein soya milk v. cow's milk to the diet of patients with severe hypercholesterolaemia and resistance to or intolerance of statins. Br J Nutr 82, 91–96.
Steinberg, FM, Guthrie, NL, Villablanca, AC, Kumar, K & Murray, MJ (2003) Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal women. Am J Clin Nutr 78, 123–130.
Teede, HJ, Dalais, FS, Kotsopoulos, D, Liang, YL, Davis, S & McGrath, BP (2001) Dietary soy has both beneficial and potentially adverse cardiovascular effects: a placebo-controlled study in men and postmenopausal women. J Clin Endocrinol Metab 86, 3053–3060.
Teixeira, SR, Potter, SM, Weigel, R, Hannum, S, Erdman, JW Jr & Hasler, CM (2000) Effects of feeding 4 levels of soy protein for 3 and 6 wk on blood lipids and apolipoproteins in moderately hypercholesterolemic men. Am J Clin Nutr 71, 1077–1084.
Tonstad, S, Smerud, K & Hoie, L (2002) A comparison of the effects of 2 doses of soy protein or casein on serum lipids, serum lipoproteins, and plasma total homocysteine in hypercholesterolemic subjects. Am J Clin Nutr 76, 78–84.
Van Horn, L, Liu, K, Gerber, J, Garside, D, Schiffer, L, Gernhofer, N & Greenland, P (2001) Oats and soy in lipid-lowering diets for women with hypercholesterolemia: is there synergy? J Am Diet Assoc 101, 1319–1325.
Vermeirssen, V, Van Camp, J & Verstraete, W (2004) Bioavailability of angiotensin I converting enzyme inhibitory peptides. Br J Nutr 92, 357–366.
Vigna, GB, Pansini, F, Bonaccorsi, G, Albertazzi, P, Donega, P, Zanotti, L, De Aloysio, D, Mollica, G & Fellin, R (2000) Plasma lipoproteins in soy-treated postmenopausal women: a double-blind, placebo-controlled trial. Nutr Metab Cardiovasc Dis 10, 315–322.
West, SG, Hilpery, KF, Juturu, V, Bordi, PL, Lampe, JW, Mousa, SA & Kris Etherton, PM (2005) Effects of including soy protein in a blood cholesterol lowering diet on markers of cardiac risk in men, and postmenopausal women +/ − hormone replacement therapy. J Womens Health (Larchmt) 14, 253–262.
Wong, WW, Smith, EO, Stuff, JE, Hachey, DL, Heird, WC & Pownell, HJ (1998) Cholesterol-lowering effect of soy protein in normocholesterolemic and hypercholesterolemic men. Am J Clin Nutr 68, 1385S–1389S.