1Bateson, P, Barker, D, Clutton-Brock, T, Deb, D, D'Udine, B, Foley, RA, Gluckman, P, Godfrey, K, Kirkwood, T, Lahr, MM, McNamara, J, Metcalfe, NB, Monaghan, P, Spencer, HG & Sultan, SE (2004) Developmental plasticity and human health. Nature 430, 419–421.
2Godfrey, KM & Barker, DJ (2001) Fetal programming and adult health. Public Health Nutr 4, 611–624.
3Langley, SC & Jackson, AA (1994) Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin Sci (Lond) 86, 217–222.
4Burdge, GC, Hanson, MA, Slater-Jefferies, JL & Lillycrop, KA (2007) Epigenetic regulation of transcription: a mechanism for inducing variations in phenotype (fetal programming) by differences in nutrition during early life? Br J Nutr 97, 1036–1046.
5Bird, A (2001) DNA methylation patterns and epigenetic memory. Genes Dev 16, 6–21.
6Burdge, GC, Phillips, ES, Dunn, RL, Jackson, AA & Lillycrop, KA (2004) Effect of reduced maternal protein consumption during pregnancy in the rat on plasma lipid concentrations and expression of peroxisomal proliferator-activated receptors in the liver and adipose tissue of the offspring. Nutr Res 24, 639–646.
7Lillycrop, KA, Phillips, ES, Jackson, AA, Hanson, MA & Burdge, GC (2005) Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 135, 1382–1386.
8Lillycrop, KA, Slater-Jefferies, JL, Hanson, MA, Godfrey, KM, Jackson, AA & Burdge, GC (2007) Induction of altered epigenetic regulation of the hepatic glucocorticoid receptor in the offspring of rats fed a protein-restricted diet during pregnancy suggests that reduced DNA methyltransferase-1 expression is involved in impaired DNA methylation and changes in histone modifications. Br J Nutr 97, 1064–1073.
9Liu, D, Diorio, J, Tannenbaum, B, Caldji, C, Francis, D, Freedman, A, Sharma, S, Pearson, D, Plotsky, PM & Meaney, MJ (1997) Maternal care, hippocampal glucocorticoid receptors, and hypothalamic–pituitary–adrenal responses to stress. Science 277, 1659–1662.
10Francis, D, Diorio, J, Liu, D & Meaney, MJ (1999) Nongenomic transmission across generations of maternal behavior and stress responses in the rat. Science 286, 1155–1158.
11Weaver, IC, Cervoni, N, Champagne, FA, D'Alessio, AC, Sharma, S, Seckl, JR, Dymov, S, Szyf, M & Meaney, MJ (2004) Epigenetic programming by maternal behavior. Nat Neurosci 7, 847–854.
12Burdge, GC, Slater-Jefferies, JL, Torrens, C, Phillips, ES, Hanson, MA & Lillycrop, KA (2007) Dietary protein restriction of pregnant rats in the F0 generation induces altered methylation of hepatic gene promoters in the adult male offspring in the F1 and F2 generations. Br J Nutr 97, 435–439.
13Mühlisch, J, Bajanowski, T, Rickert, CH, Roggendorf, W, Würthwein, G, Jürgens, H & Frühwald, MC (2007) Frequent but borderline methylation of p16 (INK4a) and TIMP3 in medulloblastoma and sPNET revealed by quantitative analyses. J Neurooncol 83, 17–29.
14Robertson, KD, Ait-Si-Ali, S, Yokochi, T, Wade, PA, Jones, PL & Wolffe, AP (2000) Dnmt1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 25, 338–342.
15Valinluck, V & Sowers, LC (2007) Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res 67, 946–950.