1. Male and female rats aged 3 weeks were divided into two groups. One group of each sex was allowed unlimited access to the stock diet, the other group was given the stock diet in restricted amounts for 10 weeks so that the males gained only 19 g and the females 21 g in comparison with 176 g and 116 g for the well-nourished males and females respectively. The undernourished animals were then rehabilitated by being allowed the stock diet ad lib.
2. Five animals of each sex were killed at various stages of the experiment, their bodies analysed for fat and nitrogen, and the size and number of fat cells determined in specific fat depots.
3. The undernourished rats failed to make a complete recovery and were significantly smaller than the controls of the same sex at 172 d of age when the experiment terminated.
4. The previously undernourished rats deposited significantly more fat in their bodies during rehabilitation than the control animals in the same number of days and over the same gain in body-weight.
5. There were no significant differences in the number of cells containing fat at the abdominal fat site between the undernourished and rehabilitated animals and the controls at any stage, nor were there any significant differences in apparent fat cell numbers between the control and rehabilitated animals at any of the other sites studied when the experiment ended at 172 d.
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