1 Denke, MA (2001) Connections between obesity and dyslipidaemia. Curr Opin Lipidol 12, 625–628.
2 Wajchenberg, BL (2000) Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 21, 697–738.
3 Valle, M, Gascón, F, Martos, R, Ruz, FJ, Bermudo, F, Morales, R & Cañete, R (2002) Metabolic cardiovascular syndrome in obese prepubertal children: the role of high fasting insulin levels. Metabolism 51, 423–428.
4 Weiss, R, Dziura, J, Burgert, TS, et al. (2004) Obesity and the metabolic syndrome in children and adolescents. N Engl J Med 350, 2362–2374.
5 Rossner, S, Walldius, G & Bjorvell, H (1989) Fatty acid composition in serum lipids and adipose tissue in severe obesity before and after six weeks of weight loss. Int J Obes 13, 603–612.
6 Phinney, SD, Tang, AB, Thurmond, DC, Nakamura, MT & Stern, JS (1993) Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by γ-linolenic acid administration. Metabolism 42, 1127–1140.
7 Garaulet, M, Pérez-Llamas, F, Pérez- Ayala, M, Martínez, P, Sánchez de Medina, F, Tébar, FJ & Zamora, S (2001) Site-specific differences in the fatty acid composition of abdominal adipose tissue in an obese population from a Mediterranean area: relation with dietary fatty acids, plasma lipid profile, serum insulin, and central obesity. Am J Clin Nutr 74, 585–591.
8 Vessby, B (2003) Dietary fat, fatty acid composition in plasma and the metabolic syndrome. Curr Opin Lipidol 14, 15–19.
9 Tremblay, AJ, Despres, JP, Piche, ME, Nadeau, A, Bergeron, J, Almeras, N, Tremblay, A & Lemieux, S (2004) Associations between the fatty acid content of triglyceride, visceral adipose tissue accumulation, and components of the insulin resistance syndrome. Metabolism 53, 310–317.
10 Agostoni, C, Riva, E, Bellu, R, Vincenzo, SS, Grazia, BM & Giovannini, M (1994) Relationships between the fatty acid status and insulinemic indexes in obese children. Prostaglandins Leukot Essent Fatty Acids 51, 317–321.
11 Scaglioni, S, Verduci, E, Salvioni, M, Bruzzese, MG, Radaelli, G, Zetterstrom, R, Riva, E & Agostoni, C (2006) Plasma long-chain fatty acids and the degree of obesity in Italian children. Acta Paediatr 95, 964–969.
12 Decsi, T, Molnár, D & Koletzko, B (1996) Long-chain polyunsaturated fatty acids in plasma lipids of obese children. Lipids 31, 305–311.
13 Decsi, T, Molnar, D & Koletzko, B (1998) The effect of under- and overnutrition on essential fatty acid metabolism in childhood. Eur J Clin Nutr 52, 541–548.
14 Decsi, T, Csabi, G, Torok, K, Erhardt, E, Minda, H, Burus, I, Molnar, S & Molnar, D (2000) Polyunsaturated fatty acids in plasma lipids of obese children with and without metabolic cardiovascular syndrome. Lipids 35, 1179–1184.
15 Klein-Platat, C, Drai, J, Oujaa, M, Schlienger, JL & Simon, C (2005) Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents. Am J Clin Nutr 82, 1178–1184.
16 Larque, E, Gil-Campos, M, Ramirez-Tortosa, MC, Linde, J, Canete, R & Gil, A (2006) Postprandial response of trans fatty acids in prepubertal obese children. Int J Obes 30, 1488–1493.
17 Haslam, DW & James, WP (2005) Obesity. Lancet 366, 1197–1209.
18 Speiser, PW, Rudolf, MC, Anhalt, H, et al. (2005) Childhood obesity. J Clin Endocrinol Metab 90, 1871–1887.
19 Cruz, ML, Shaibi, GQ, Weigensberg, MJ, Spruijt-Metz, D, Ball, GD & Goran, MI (2005) Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment and prevention beyond body weight modification. Annu Rev Nutr 25, 435–468.
20 Tanner, JM (1962) Growth at Adolescence: with a General Consideration of the Effects of Hereditary and Environmental Factors upon Growth and Maturation from Birth to Maturity, 2nd ed. Oxford, UK: Blackwell Scientific.
21 Hernández, M, Castellet, J, Narvaiza, JL, Rincón, JM, Ruiz, E, Sánchez, E, Sobradillo, B & Zurimendi, A (2002) Curvas y Tablas de Crecimiento. Instituto de Investigación sobre Crecimiento y Desarrollo. Fundación Faustino Orbegozo. Madrid: Ergón Press.
22 Hernández, M (2002) El patrón de crecimiento humano y su evaluación (The pattern of human growth and its evaluation). In Tratado de Endocrinología Pediátrica, 3rd ed., pp.253–262 [Pombo, M, editor]. Madrid: McGraw-Hill Interamericana Press.
23 Martínez-Victoria, E & Mañas, M (2002) Alimentación y Salud. . Asde, Valencia: Universidad de Granada.
24 Matthews, DR, Hosker, JP, Rudenski, AS, Naylor, BA, Treacher, DF & Turner, RC (1985) Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412–419.
25 Katz, A, Nambi, SS, Mather, K, Baron, AD, Follmann, DA, Sullivan, G & Quon, MJ (2000) Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85, 2402–2410.
26 Larqué, E, Demmelmair, H, Berger, B, Hasbargen, U & Koletzko, B (2003) In vivo investigation of the placental transfer of 13C-labeled fatty acids in humans. J Lipid Res 44, 49–55.
27 Kolarovic, L & Fournier, NC (1986) A comparison of extraction methods for the isolation of phospholipids from biological sources. J Ann Biochem 156, 244–250.
28 Agren, JJ, Julkunen, A & Penttila, I (1992) Rapid separation of serum lipids for fatty acid analysis by a single aminopropyl column. J Lipid Res 33, 1871–1876.
29 Lepage, G & Roy, CC (1986) Direct transesterification of all classes of lipids in one-step reaction. J Lipid Res 27, 114–120.
30 Ramírez, M, Gallardo, EM, Souto, AS, Weissheimer, C & Gil, A (2001) Plasma fatty-acid composition and antioxidant capacity in low-birth weight infants fed formula enriched with n-6 and n-3 long-chain polyunsaturated fatty acids from purified phospholipids. Clin Nutr 20, 69–76.
31 Amate, L, Gil, A & Ramirez, M (2001) Feeding infant piglets formula with long-chain polyunsaturated fatty acids as triacylglycerols or phospholipids influences the distribution of these fatty acids in plasma lipoprotein fractions. J Nutr 131, 1250–1255.
32 Cabré, E, Periago, JL, Abad-Lacruz, A, Gil, A, González-Huix, F, Sánchez-Medina, F & Gassull, MA (1988) Polyunsaturated fatty acid deficiency in liver cirrhosis: its relation to associated protein-energy malnutrition (Preliminary report). Am J Gastroenterol 83, 712–717.
33 Esteve, M, Ramírez, M, Fernández-Bañares, F, et al. (1992) Plasma polyunsaturated fatty acid pattern in active inflammatory bowel disease. Gut 33, 1365–1369.
34 Reaven, G (1998) Role of insulin resistance in human disease. Diabetes 37, 1595–1607.
35 Reaven, GM (2005) Why syndrome X? From Harold Himsworth to the insulin resistance syndrome. Cell Metab 1, 9–13.
36 Ramirez-Tortosa, MC, Suarez, A, Gomez, MC, Mir, A, Ros, E, Mataix, J & Gil, A (1999) Effect of extra-virgin olive oil and fish-oil supplementation on plasma lipids and susceptibility of low-density lipoprotein to oxidative alteration in free-living Spanish male patients with peripheral vascular disease. Clin Nutr 18, 167–174.
37 Phinney, SD, Davis, PG, Johnson, SB & Holman, RT (1991) Obesity and weight loss alter serum polyunsaturated lipids in humans. Am J Clin Nutr 53, 831–838.
38 Kunesova, M, Hainer, V, Tvrzicka, E, Phinney, SD, Stich, V, Parizkova, J, Zak, A & Stunkard, AJ (2002) Assessment of dietary and genetic factors influencing serum and adipose fatty acid composition in obese female identical twins. Lipids 37, 27–32.
39 Phinney, SD (2005) Fatty acids, inflammation and metabolic syndrome. Am J Clin Nutr 82, 1151–1152.
40 Hu, CC, Qing, K & Chen, Y (2004) Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice. Obes Res 12, 1264–1270.
41 Sampath, H & Ntambi, JM (2006) Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferator-activated receptor-α: independent and interactive roles in the regulation of lipid metabolism. Curr Opin Clin Nutr Metab Care 9, 84–88.
42 Aldamiz-Echevarria, L, Prieto, JA, Andarde, F, Elorz, J, Sanjurjo, P & Rodriguez-Soriano, J (2007) Arachidonic acid content in adipose tissue is associated with insulin resistance in healthy children. J Pediat Gastroenterol Nutr 44, 77–83.