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The β-carotene-rich alga Dunaliella bardawil as a source of retinol in a rat diet

Published online by Cambridge University Press:  09 March 2007

A. Ben-Amotz ,
S. Mokady  and
M. Avron
A. Ben-Amotz
Affiliation:
Israel Oceanographic and Limnological Research, Tel-Shikmona, PO Box 8030, Haifa 31080, Israel
S. Mokady
Affiliation:
Department of Food Engineering and Biotechnology, Technion, Haifa 32000, Israel
M. Avron
Affiliation:
Biochemistry Department, The Weizmann Institute of Science, Rehovot 76100, Israel
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Abstract

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1. Dunaliella bardawil, a β-carotene-accumulating alga, has been tested as a source of retinol and β-carotene in a diet given to rats. The β-carotene in this alga is composed of about equal amounts of the 9-cis and all-trans isomers. Male weanling rats were fed on a retinol-deficient diet for 60 d. Thereafter, the rats were divided into groups and fed on a diet deficient in retinol or supplemented with retinol, synthetic β-carotene, dry alga or an algal oil-extract. Following further growth for 7 d, samples were taken for liver analyses of retinol, retinol isomers and β-carotene.

2. Liver analyses revealed a comparable content of retinol and normal conversion rates in the rats grown on the diets supplemented with synthetic or natural β-carotene. Rats fed on the alga and the algal-oil-supplemented diets accumulated 9-cis retinol in addition to the all-trans isomer. Rats fed on synthetic β-carotene, alga and algal oil had a liver retinol: β-carotene value of about 3:1.

3. These studies demonstrate the possibility of using dried D. bardawil or an oil extract of the alga as a dietary natural β-carotene supplement which satisfies the total requirement of retinol in rats.

4. Rats fed on alga or on algal oil, accumulated in the liver 9-cis β-carotene and all-trans β-carotene in a ratio similar to that present in the alga.

Type
Research Article
Information
British Journal of Nutrition , Volume 59 , Issue 3 , May 1988 , pp. 443 - 449
Copyright
Copyright © The Nutrition Society 1988

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