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Association of sugar-sweetened beverage intake at 18 months and 5 years of age with adiposity outcomes at 6 years of age: the Singapore GUSTO mother–offspring cohort

  • Phaik Ling Quah (a1), Josefien Kleijweg (a1), Ya Yin Chang (a1), Jia Ying Toh (a1), Hui Xian Lim (a1), Ray Sugianto (a2), Izzuddin M. Aris (a1) (a3), Wen Lun Yuan (a4), Mya Thway Tint (a3), Jonathan Y. Bernard (a1) (a5), Padmapriya Natarajan (a3), Falk Müller-Riemenschneider (a2) (a6), Keith M. Godfrey (a7), Peter D. Gluckman (a1) (a8), Yap-Seng Chong (a1) (a3), Lynette P. Shek (a1) (a4) (a9), Kok Hian Tan (a10) (a11), Johan G. Eriksson (a3) (a12) (a13) (a14), Fabian Yap (a11) (a15) (a16), Yung Seng Lee (a1) (a4) (a17) and Mary F. F. Chong (a1) (a2)...


Consumption of sugar-sweetened beverages (SSB) by infants and young children are less explored in Asian populations. The Growing Up in Singapore Towards healthy Outcomes cohort study examined associations between SSB intake at 18 months and 5 years of age, with adiposity measures at 6 years of age. We studied Singaporean infants/children with SSB intake assessed by FFQ at 18 months of age (n 555) and 5 years of age (n 767). The median for SSB intakes is 28 (interquartile range 5·5–98) ml at 18 months of age and 111 (interquartile range 57–198) ml at 5 years of age. Association between SSB intake (100 ml/d increments and tertile categories) and adiposity measures (BMI standard deviation scores (sd units), sum of skinfolds (SSF)) and overweight/obesity status were examined using multivariable linear and Poisson regression models, respectively. After adjusting for confounders and additionally for energy intake, SSB intake at age 18 months were not significantly associated with later adiposity measures and overweight/obesity outcomes. In contrast, at age 5 years, SSB intake when modelled as 100 ml/d increments were associated with higher BMI by 0·09 (95 % CI 0·02, 0·16) sd units, higher SSF thickness by 0·68 (95 % CI 0·06, 1·44) mm and increased risk of overweight/obesity by 1·2 (95 % CI 1·07, 1·23) times at age 6 years. Trends were consistent with SSB intake modelled as categorical tertiles. In summary, SSB intake in young childhood is associated with higher risks of adiposity and overweight/obesity. Public health policies working to reduce SSB consumption need to focus on prevention programmes targeted at young children.


Corresponding author

*Corresponding author: Dr Mary F. F. Chong, email


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Association of sugar-sweetened beverage intake at 18 months and 5 years of age with adiposity outcomes at 6 years of age: the Singapore GUSTO mother–offspring cohort

  • Phaik Ling Quah (a1), Josefien Kleijweg (a1), Ya Yin Chang (a1), Jia Ying Toh (a1), Hui Xian Lim (a1), Ray Sugianto (a2), Izzuddin M. Aris (a1) (a3), Wen Lun Yuan (a4), Mya Thway Tint (a3), Jonathan Y. Bernard (a1) (a5), Padmapriya Natarajan (a3), Falk Müller-Riemenschneider (a2) (a6), Keith M. Godfrey (a7), Peter D. Gluckman (a1) (a8), Yap-Seng Chong (a1) (a3), Lynette P. Shek (a1) (a4) (a9), Kok Hian Tan (a10) (a11), Johan G. Eriksson (a3) (a12) (a13) (a14), Fabian Yap (a11) (a15) (a16), Yung Seng Lee (a1) (a4) (a17) and Mary F. F. Chong (a1) (a2)...


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