Skip to main content Accessibility help
×
Home

Stress neuroendocrine profiles in five pig breeding lines and the relationship with carcass composition

  • A. Foury (a1), N. A. Geverink (a1), M. Gil (a2), M. Gispert (a2), M. Hortós (a2), M. Font i Furnols (a2), D. Carrion (a3), S. C. Blott (a4), G. S. Plastow (a4) and P. Mormède (a1)...

Abstract

Stress neuroendocrine systems (hypothalamic–pituitary–adrenal axis and sympathetic nervous system) were studied in 100 female pigs from each of the five main genetic lines used in Europe for pork production: Piétrain, Large White, Landrace, Duroc and Meishan. Levels of cortisol and catecholamines were measured in urine collected at the farm, after transportation to the slaughterhouse and the next morning before slaughter. With the exception of the Piétrain line that showed intermediate levels of cortisol despite its extreme leanness, a significant positive relationship was found between basal cortisol levels and fatness, both across and within (except in Piétrain and Duroc) lines. Basal cortisol levels were 2.46-fold higher in Meishan (20.46 ng/mg creatinine) than in Large White pigs (8.30 ng/mg creatinine), the two extreme breeds. Post-transportation levels were highest but proportional to basal levels, suggesting that the adrenal reactivity to adrenocorticotropic hormone is a major source of variability between lines. Levels of catecholamines were less variable between lines but correlated also with fatness, partlyviapartial correlations with cortisol levels. In serum collected at exsanguination, creatine kinase activity was correlated with muscularity across the five breeds. However, this was due to a much larger activity than expected in Piétrain pigs, although all animals were negative for the allele of the ryanodine receptor gene responsible for stress sensitivity. Serum glucose levels were inversely related to fatness. These data show that the differences between breeds or lines can be utilised by cross-breeding and that this can lead to changes in stress hormones and in turn to some degree of changes in carcass traits.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Stress neuroendocrine profiles in five pig breeding lines and the relationship with carcass composition
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Stress neuroendocrine profiles in five pig breeding lines and the relationship with carcass composition
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Stress neuroendocrine profiles in five pig breeding lines and the relationship with carcass composition
      Available formats
      ×

Copyright

Corresponding author

References

Hide All
Bergeron, R, Gonyou, HW, Eurell, TE 1996. Behavioral and physiological responses of Meishan, Yorkshire and crossbred gilts to conventional and turn-around gestation stalls. Canadian Journal of Animal Science 76, 289297.
Bickhardt, K 1969. Ein enzymatisches verfahren zur erkennung von muskelschäden beim lebenden schwein. Deutsche Tierärztliche Wochenschrift 76, 601624.
Bidanel, JP, Caritez, JC, Gruand, J, Legault, C 1993. Growth, carcass and meat quality performance of crossbred pigs with graded proportions of Meishan genes. Genetics, Selection, Evolution 25, 8399.
Bonneau, M 1993. Growth hormone response to GRF and insulin-induced hypoglycemia in yorkshire and Meishan pigs. American Journal of Physiology 264, E54E59.
Boyd, JW 1983. The mechanisms relating to increases in plasma enzymes and isoenzymes in diseases of animals. Veterinary Clinical Pathology 12, 924.
Bright, GM, Darmaun, D 1995. Corticosteroid-binding globulin modulates cortisol concentration responses to a given production rate. Journal of Clinical Endocrinology and Metabolism 80, 764769.
Ciaranello, RD 1978. Regulation of phenylethanolamine N-methyltransferase. Biochemical Pharmacology 27, 18951897.
Crockett, CM, Bowers, CL, Sackett, GP, Bowden, DM 1993. Urinary cortisol responses of longtailed macaques to five cage sizes, tethering, sedation and room change. American Journal of Primatology 30, 5574.
Dallman, MF, Strack, AM, Akana, SF, Bradbury, MJ, Hanson, ES, Scribner, KA, Smith, M 1993. Feast and famine: critical role of glucocorticoids with insulin in daily energy flow. Frontiers in Neuroendocrinology 14, 303347.
DeRijk, RH, Schaaf, M, de Kloet, ER 2002. Glucocorticoid receptor variants: clinical implications. Journal of Steroid Biochemistry and Molecular Biology 81, 103122.
Désautés, C, Bidanel, JP, Mormède, P 1997. Genetic study of behavioral and pituitary-adrenocortical reactivity in response to an environmental challenge in pigs. Physiology and Behavior 62, 337345.
Désautés, C, Sarrieau, A, Caritez, JC, Mormède, P 1999. Behavior and pituitary–adrenal function in Large White and Meishan pigs. Domestic Animal Endocrinology 16, 193205.
Deufel, T, Golla, A, Iles, D, Meindl, A, Meitinger, T, Schindelhauer, D, DeVries, A, Pongratz, D, MacLennan, DH, Johnson, KJ, Lehman-Horn, F 1992. Evidence for genetic heterogeneity of malignant hyperthermia susceptibility. American Journal of Human Genetics 50, 11511161.
Devenport, L, Knehans, A, Sundstrom, A, Thomas, T 1989. Corticosterone’s dual metabolic actions. Life Sciences 45, 13891396.
Dhillo, WS, Kong, WM, Le Roux, CW, Alaghband-Zadeh, J, Jones, J, Carter, G, Mendoza, N, Meeran, K, O’Shea, D 2002. Cortisol-binding globulin is important in the interpretation of dynamic tests of the hypothalamic–pituitary–adrenal axis. European Journal of Endocrinology 146, 231235.
Fernandez, X, Tornberg, E 1991. A review of the causes of variation in muscle glycogen content and ultimate pH in pigs. Journal of Muscle Foods 2, 209235.
Fletcher, JE, Calvo, PA, Rosenberg, H 1993. Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation. British Journal of Anaesthesia 71, 410417.
Foury, A, Devillers, N, Sanchez, MP, Griffon, H, Le Roy, P, Mormède, P 2005. Stress hormones, carcass composition and meat quality in Large White × Duroc pigs. Meat Science 69, 703707.
Fuji, J, Otsu, K, Zorzato, F, De Leon, S, Khanna, VK, Weiler, JE, O’Brien, PJ, MacLennan, DH 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science 253, 448451.
Geverink, NA, Foury, A, Plastow, GS, Gil, M, Gispert, M, Hortos, M, Font i Furnols, M, Gort, G, Moisan, MP, Mormède, P 2006. Cortisol-binding globulin and meat quality in five European lines of pigs. Journal of Animal Science 84, 204211.
Gispert, M, Diestre, A 1994. Classement des carcasses de porc en Espagne: un pas vers l’harmonisation communautaire. Techniporc 17, 2932.
Guyonnet-Duperat, V, Geverink, N, Plastow, GS, Evans, G, Ousova, O, Croisetière, C, Foury, A, Richard, E, Mormède, P, Moisan, MP 2006. Functional implication of an Arg307Gly substitution in corticosteroid-binding globulin, a candidate gene for a quantitative trait locus associated with cortisol variability and obesity in pig. Genetics 173, 21432149.
Hay, M, Mormède, P 1997a. Determination of catecholamines and methoxycatecholamines excretion patterns in pig and rat urine by ion-exchange liquid chromatography with electrochemical detection. Journal of Chromatography B: Biomedical Sciences and Applications 703, 1523.
Hay, M, Mormède, P 1997b. Improved determination of urinary cortisol and cortisone, or corticosterone and 11-dehydrocorticosterone by high-performance liquid chromatography with ultraviolet absorbance detection. Journal of Chromatography B: Biomedical Sciences and Applications 702, 3339.
Hay, M, Mormède, P 1998. Urinary excretion of catecholamines, cortisol and their metabolites in Meishan and Large White sows: validation as a non invasive and integrative assessment of adrenocortical and sympathoadrenal axis activity. Veterinary Research 29, 119128.
Hennessy, DP, Stelmasiak, T, Johnston, NE, Jackson, PN, Outch, KH 1988. Consistent capacity for adrenocortical response to ACTH administration in pigs. American Journal of Veterinary Research 49, 12761283.
Klont, RE, Lambooy, E, Van Logtestijn, JG 1993. Effect of preslaughter anesthesia on muscle metabolism and meat quality of pigs of different halothane genotypes. Journal of Animal Science 71, 14771485.
Leenhouwers, JI, Knol, EF, De Groot, PN, Vos, H, Van der Lende, T 2002. Fetal development in the pig in relation to genetic merit for piglet survival. Journal of Animal Science 80, 17591770.
Legault, CvCaritez, JC 1982. Premier bilan de l’expérimentation sur le porc chinois en France. 1- Performances de reproduction en race pure et en croisement. Journées de la Recherche Porcine en France 14, 127136.
Marissal-Arvy, N, Lombes, M, Petterson, J, Moisan, MP, Mormède, P 2004. Gain of function mutation in the mineralocorticoid receptor of the Brown Norway rat. Journal of Biological Chemistry 279, 3923239239.
Marple, DN, Cassens, RG, Topel, DG, Christian, LL 1974. Porcine corticosteroid-binding globulin: binding properties and levels in stress-susceptible swine. Journal of Animal Science 38, 12241228.
Monin, G 2003. Abattage des porcs et qualités des carcasses et des viandes. INRA Productions Animales 16, 251262.
Monnier, N, Krivosic-Horber, R, Payen, JF, Kozak-Ribbens, G, Nivoche, Y, Adnet, P, Reyford, H, Lunardi, J 2002. Presence of two different genetic traits in malignant hyperthermia families: implication for genetic analysis, diagnosis, and incidence of malignant hyperthermia susceptibility. Anesthesiology 97, 10671074.
Mormède P 2007. Assessment of pig welfare. In The welfare of pigs (ed. L Faucitano, J Ludke and O Dalla Costa), in press.
Mormède, P, Dantzer, R 1978. Behavioural and pituitary–adrenal characteristics of pigs differing by their susceptibility to the malignant hyperthermia syndrome induced by halothane anesthesia. 2. Pituitary–adrenal function. Annals of Veterinary Research 9, 569576.
Mormède P, Andanson S, Auperin B, Beerda B, Guémené D, Malmkvist J, Manteca X, Manteuffel G, Prunet P, Van Reenen CG, Richard S, and Veissier I 2007. Exploration of the hypothalamic–pituitary–adrenal function as a tool to evaluate animal welfare. Physiology and Behavior, doi:10.1016/j.physbeh.2006.12.003, in press.
Murani, E, Ponsuksili, S, Schellander, K, Wimmers, K 2006. Association of corticotropin-releasing hormone gene variation with performance and meat quality traits in commercial pig lines. Animal Genetics 37, 509512.
Navegantes, LCC, Migliorini, RH, Kettelhut, IC 2002. Adrenergic control of protein metabolism in skeletal muscle. Current Opinion in Clinical Nutrition and Metabolic Care 5, 281286.
Ousova, O, Guyonnet-Duperat, V, Iannuccelli, N, Bidanel, JP, Milan, D, Genet, C, Llamas, B, Yerle, M, Gellin, J, Chardon, P, Emptoz-Bonneton, A, Pugeat, M, Mormède, P, Moisan, MP 2004. Corticosteroid binding globulin: a new target for cortisol-driven obesity. Molecular Endocrinology 18, 16871696.
Pérez, MP, Palacio, J, Santolaria, MP, Acena, MC, Chacon, G, Verde, MT, Calvo, JH, Zaragoza, MP, Gascon, M, Garcia-Belenguer, S 2002. Influence of lairage time on some welfare and meat quality parameters in pigs. Veterinary Research 33, 239250.
Plastow, GS, Carrión, D, Gil, M, García-Regueiro, JA, Font i Furnols, M, Gispert, M, Oliver, MA, Velarde, A, Guàrdia, MD, Hortós, M, Rius, MA, Sárraga, C, Díaz, I, Valero, A, Sosnicki, A, Klont, R, Dornan, S, Wilkinson, JM, Evans, G, Sargent, C, Davey, G, Connolly, D, Houeix, B, Maltin, CM, Hayes, HE, Anandavijayan, V, Foury, A, Geverink, N, Cairns, M, Tilley, RE, Mormède, P, Blott, SC 2005. Review. Quality pork genes and meat production. Meat Science 70, 409421.
Pomar, C, Rivest, J, Jean dit Bailleul, P, Marcoux, M 2001. Predicting loin-eye area from ultrasound and grading probe measurements of fat and muscle depths in pork carcasses. Canadian Journal of Animal Science 81, 429434.
Richter, A, Gerdes, C, Loscher, W 1992. Atypical reactions to halothane in a subgroup of homozygous malignant hyperthermia (MH)-susceptible pigs: indication of a heterogenous genetic basis for the porcine syndrome. Deutsche Tierärztliche Wochenschrift 99, 401406.
Rosochacki, SJ, Piekarzewska, AB, Poloszynowicz, J, Sakowski, T 2000. The influence of restraint immobilization stress on the concentration of bioamines and cortisol in plasma of Pietrain and Duroc pigs. Journal of Veterinary Medicine Series A 47, 231242.
Scheurink, AJ, Steffens, AB 1990. Central and peripheral control of sympathoadrenal activity and energy metabolism in rats. Physiology and Behavior 48, 909920.
Schmidt, E, Schmidt, FW 1987. Enzyme release. Journal of Clinical Chemistry and Clinical Biochemistry 25, 525540.
Seewald, MJ, Eichinger, HM, Lehman-Horn, F, Iaizzo, PA 1991. Characterization of swine susceptible to malignant hyperthermia both in vivo, in vitro and post-mortem techniques. Acta Anaesthesiologica Scandinavica 35, 345349.
Statistical Analysis Systems Institute 2000. Staistics version 8.02. SAS Inst., Inc., Cary, NC.
Volfinger, L, Lassourd, V, Michaux, JM, Braun, JP, Toutain, PL 1994. Kinetic evaluation of muscle damage during exercise by calculation of creatine kinase released. American Journal of Physiology 266, R434R441.
Walstra, P, Merkus, GSM 1995. Procedure for the assessment of lean meat percentage as a consequence of the new EU reference dissection method in pig carcass classification. DLO – Research Institute of Animal Science and Health (ID-DLO), Zeist, The Netherlands.
Warriss, PD, Brown, SN, Edwards, JE, Knowles, TG 1998. Effect of lairage time on levels of stress and meat quality in pigs. Animal Science 66, 255261.
Weiler, U, Claus, R, Schnoebelen-Combes, S, Louveau, I 1998. Influence of age and genotype on endocrine parameters and growth performance: a comparative study in Wild boars, Meishan and Large White boars. Livestock Production Science 54, 2131.
Wise, T, Klindt, J, Howard, HJ, Conley, AJ, Ford, JJ 2001. Endocrine relationships of Meishan and White composite females after weaning and during the luteal phase of the estrous cycle. Journal of Animal Science 79, 176187.
Zhang, SH, Hennessy, DP, Cranwell, PD 1990. Pituitary and adrenocortical responses to corticotropin-releasing factor in pigs. American Journal of Veterinary Research 51, 10211025.
Zhang, SH, Hennessy, DP, Cranwell, PD, Noonan, GJ, Francis, HJ 1992. Physiological responses to exercise and hypoglycemia stress in pig of differing adrenal responsiveness. Comparative Biochemistry and Physiology (A) 103, 695703.

Keywords

Stress neuroendocrine profiles in five pig breeding lines and the relationship with carcass composition

  • A. Foury (a1), N. A. Geverink (a1), M. Gil (a2), M. Gispert (a2), M. Hortós (a2), M. Font i Furnols (a2), D. Carrion (a3), S. C. Blott (a4), G. S. Plastow (a4) and P. Mormède (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed