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Genetic analysis of insect bite hypersensitivity (summer eczema) in Icelandic horses

  • S. Eriksson (a1), K. Grandinson (a1), W. F. Fikse (a2), L. Lindberg (a1), S. Mikko (a1), H. Broström (a3), R. Frey (a4), M. Sundquist (a5) and G. Lindgren (a6)...

Abstract

There is a lack of knowledge about the genetic background of eczema due to insect bite hypersensitivity, also called summer eczema, in horses. The condition is known in several horse breeds and countries and it causes reduced welfare of the horse and economic losses to the owner. The aim of this study was to estimate genetic parameters for summer eczema in Swedish-born Icelandic horses. A questionnaire was sent to owners of horses sired by stallions with more than 50 offspring born in Sweden between 1991 and 2001. Variance components of summer eczema classified as healthy, mild, moderate or severe were estimated using the threshold methodology with sire models. In addition, summer eczema was analysed as a binary trait (healthy v. affected). The analyses included 1250 horses sired by 33 stallions. The prevalence of summer eczema was 8%, with a range of 0% to 30% in different paternal half-sib groups. Offspring of dams suffering from eczema had a higher risk of developing eczema. The heritability for severity of summer eczema was estimated at 0.3 (s.d. < 0.2) with a threshold sire model. In contrast to the age of the horse, different geographic areas and gender were significantly associated with severity of the eczema. We conclude that genetic selection could decrease the prevalence of summer eczema among Swedish-born Icelandic horses. The amount and quality of data are, however, crucial for the possibility to introduce a genetic evaluation of summer eczema. The symptoms should be classified in several classes according to severity, and this classification could be made by the horse owner.

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Corresponding author

E-mail: Susanne.Eriksson@hgen.slu.se

References

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Anderson, GS, Belton, P, Kleider, N 1988. The hypersensitivity of horses to Culicoides bites in British Columbia. Canadian Veterinary Journal 29, 718723.
Anderson, GS, Belton, P, Kleider, N 1993. Hypersensitivity of horses in British Columbia to extracts of native and exotic species of Culicoides (Diptera: Ceratopogonidae). Journal of Medical Entomology 30, 657663.
Árnason Th, Sigurdsson Á and Lorange JB 2006. Global genetic evaluations of the Icelandic horse and genetic connectedness between countries. Proceedings of the eighth world congress on genetics applied to livestock production, Belo Horizonte, Brazil. CD-ROM communication no 24-16.
Björnsdóttir, S, Sigvaldadottir, J, Broström, H, Langvad, B, Sigurdsson, A 2006. Summer eczema in exported Icelandic horses: influence of environmental and genetic factors. Acta Veterinaria Scandinavica 1, 3.
Braverman, Y, Ungar-Waron, H, Frith, K, Adler, K, Danieli, Y, Baker, K, Quinn, PJ 1983. Epidemiological and immunological studies of sweet itch in horses in Israel. Veterinary Record 112, 521524.
Broström, H, Larsson, Å, Troedsson, M 1987. Allergic dermatitis (sweet itch) of Icelandic horses in Sweden: an epidemiological study. Equine Veterinary Journal 19, 229236.
Cagienard, A, Griot, C, Mellor, PS, Denison, E, Stärk, KDC 2006. Bluetongue vector species of Culicoides in Switzerland. Medical and Veterinary Entomology 20, 239247.
Gianola, D 1982. Theory and analysis of threshold characters. Journal of Animal Science 54, 10791096.
van Grevenhof EM, Ducro B, Heuven HCM and Bijma P 2006. Environmental and genetic factors affecting prevalence of insect bite hypersensitivity in Shetland and Friesian horses in the Netherlands. Proceedings of the eighth world congress on genetics applied to livestock production, Belo Horizonte, Brazil. CD-ROM communication no 08-10.
van Grevenhof, EM, Ducro, B, Heuven, HCM, Bijma, P 2007. Identification of environmental factors affecting the prevalence of insect bite hypersensitivity in Shetland and Friesian horses in the Netherlands. Equine Veterinary Journal 39, 6975.
Halldórsdóttir, S, Larsen, HJ 1991. An epidemiological study of summer eczema in Icelandic horses in Norway. Equine Veterinary Journal 23, 296299.
Hellberg, W, Wilson, AD, Mellor, P, Doherr, MG, Torsteinsdottir, S, Zurbriggen, A, Jungi, T, Marti, E 2006. Equine insect bite hypersensitivity: Immunoblot analysis of IgE and IgG subclass responses to Culicoides nubeculosus salivary gland extract. Veterinary Immunology and Immunopathology 113, 99112.
Janss L 2007. iBay manual version 1.31.
Kadarmideen, HN, Janss, LLC 2005. Evidence of a major gene from Bayesian segregation analysis of liability to osteochondral disease in pigs. Genetics 171, 11951206.
Kettle, DS 1977. Biology and bionomics of bloodsucking ceratopogonids. Annual Review of Entomology 22, 3351.
Lange, S, Hamann, H, Deegen, E, Ohnesorge, B, Distl, O 2005. Untersuchung der Prävalenz des Sommerekzems beim Islandspferd in Norddeutschland. Berliner und Münchener Tierarztliche Wochenschift 118, 481489.
Larsen, HJ, Bakke, SH, Mehl, R 1988. Intradermal challenge of Icelandic horses in Norway and Iceland with extracts of Culicoides spp. Acta Veterinaria Scandinavica 29, 311314.
Marti, E, Gerber, H, Lazary, S 1992. On the genetic basis of equine allergic diseases: II. Insect bite dermal hypersensitivity. Equine Veterinary Journal 24, 113117.
McCaig, J 1973. Survey to establish the incidence of sweet itch in ponies in the United Kingdom. Veterinary Record 93, 444446.
Mellor, PS 1974. The probable cause of “sweet itch” in England. Veterinary Record 95, 411415.
Raich, T, Jacobson, M, Holbrook, F, Babion, R, Blair, C, Beaty, B 1997. Culicoides variipennis (Diptera: Ceratopogonidae) host selection in Colorado. Journal of medical entomology 34, 247249.
Reiher RJ, Björnsdóttir S 2004. The prevalence of summer eczema in Icelandic horses born in Germany. International Symposium on Diseases of the Icelandic Horse, Veterinary Association Icelandic (Ed.). International Veterinary Information Service, Ithaca NY, USA. P1121.0604. Retrieved November 17, 2006 from www.ivis.org.
Riek, RF 1953a. Studies on allergic dermatitis (“Queensland itch”) of the horse. Australian Journal of Agricultural Research 29, 177184.
Riek, RF 1953b. Studies on allergic dermatitis of the horse II – treatment and control. Australian Journal of Agricultural Research 29, 185187.
Statistical Analysis Systems Institute 2004. SAS cnlinedoc® 9.1.3. SAS Institute Inc., Cary, NC. Retrieved October 10, 2006, from http://support.sas.com/onlinedoc/913/.
von Unkel, M, Simon, D, Mayer, M, Sommer, H 1987. Zur genetischen Fundierung des Sommerekzems beim Islandspferd. Journal of Animal Breeding and Genetics 104, 217230.
Wang CS 1998. Implementation issues in Bayesian analysis in animal breeding. Proceedings of the sixth world congress on genetics applied to livestock production, Armidale, Australia, vol. 25, pp. 481–488.
Wilson, AD, Harwood, LJ, Björnsdóttir, S, Marti, E, Day, MJ 2001. Detection of IgG and IgE serum antibodies to Culicoides salivary gland antigens in horses with insect dermal hypersensitivity (sweet itch). Equine Veterinary Journal 33, 707713.

Keywords

Genetic analysis of insect bite hypersensitivity (summer eczema) in Icelandic horses

  • S. Eriksson (a1), K. Grandinson (a1), W. F. Fikse (a2), L. Lindberg (a1), S. Mikko (a1), H. Broström (a3), R. Frey (a4), M. Sundquist (a5) and G. Lindgren (a6)...

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