Baum, JA, Teng, H, Erdman, JW Jr, Weigel, RM, Klein, BP, Persky, VW, Freels, S, Surya, P, Bakhit, RM, Ramos, E, Shay, NF, Potter, SM 1998. Long-term intake of soy protein improves blood lipid profiles and increases mononuclear cell low-density-lipoprotein receptor messenger RNA in hypercholesterolemic, postmenopausal women. The American journal of Clinical Nutrition 68, 545–551.
Dodds, WJ 1982. The pig model for biomedical research. Federation Proceeding 41, 247–256.
Dorado, M, Martin Gomez, EM, Jimenez-Colmenero, F, Masoud, TA 1999. Cholesterol and fat contents of Spanish commercial pork cuts. Meat Science 51, 321–323.
Duckworth, PF, Vlahcevic, ZR, Studer, EJ, Gurley, EC, Heuman, DM, Beg, ZH, Hylemon, PB 1991. Effect of hydrophobic bile acid on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and mRNA levels in the rat. The Journal of Biological Chemistry 266, 9413–9418.
Favy, DA, Lafarge, S, Rio, P, Vissac, C, Bignon, YJ, Bernard-Gallon, D 2000. Real-time PCR quantification of full-length and exon 11 spliced BRCA1 transcripts in human breast cancer cell lines. Biochemical and Biophysical Research Communications 274, 73–78.
Fink, L, Seeger, W, Ermert, L, Hanze, J, Stahl, U, Grimminger, F, Kummer, W, Bohle, RM 1998. Real-time quantitative RT-PCR after laser-assisted cell picking. Nature Medicine 4, 1329–1333.
Ha, SH, Kim, JB, Hwang, YS, Lee, SW 2003. Molecular characterization of three 3-hydroxy-3-methylglutaryl-CoA reductase genes including pathogen-induced Hmg2 from pepper (Capsicum annuum). Biochima Biophysica Acta 1625, 253–260.
Harris, KB, Pond, WG, Mersmann, HJ, Smith, EO, Cross, HR, Savell, JW 2004. Evaluation of fat sources on cholesterol and lipoproteins using pigs selected for high or low serum cholesterol. Meat Science 66, 55–61.
Humphries, SE, Tata, F, Henry, I, Barichard, F, Holm, M, Junien, C, Williamson, R 1985. The isolation, characterization, and chromosomal assignment of the gene for human hydroxyl 3-methylglutaryl coenzyme A reductase (HMG-CoA reductase). Human Genetics 71, 254–258.
Istvan, ES, Deisenhofer, J 2000. The structure of the catalytic portion of human HMG-CoA reductase. Biochimica Biophysica Acta 1529, 9–18.
Jiang, JH, Kai, GY, Cao, XY, Chen, FM, He, DN, Liu, Q 2006. Molecular cloning of a HMG-CoA reductase gene from Eucommia ulmoides Oliver. Bioscience Reports 26, 171–181.
Lee, KT, Kim, DN, Thomas, WA 1986. Atherosclerosis in swine. CRC Press, Boca Raton, FL, USA.
Leveille, GA, Romsos, DR, Yeh, Y, O’Hea, EK 1975. Lipid biosynthesis in the chick. A consideration of site of synthesis, influence of diet and possible regulatory mechanisms. Poultry Science 54, 1075–1093.
Lord, E, Murphy, BD, Desmarais, JA, Ledoux, S, Beaudry, D, Palin, MF 2006. Modulation of peroxisome proliferator-activated receptorδ and γtranscripts in swine endometrial tissue during early gestation. Reproduction 131, 929–942.
Luskey, KL, Stevens, B 1985. Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation. The Journal of Biological Chemistry 260, 10271–10277.
Myant, NB 1990. Current approaches to the genetics of coronary heart disease (CHD) including an account of work done at Hammersmith Hospital. Bollettino della Società italiana di biologia sperimentale 66, 1015–1041.
Ness, GC 2003. Physiological and pharmacological regulation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase. Current Medicinal Chemistry-Imunology, Endocrine & Metabolic Agents 3, 219–227.
Pond, WG, Mersmann, HJ, Young, LD 1986. Heritability of plasma cholesterol and triglyceride concentrations in swine. Proceedings of the Society for Experimental Biology and Medicine 182, 221–224.
Rasmusseen, LM, Hanzen, PR, Nabipour, MT, Olesen, P, Kristiansen, MT, Ledet, T 2001. Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells. The Biochemical Journal 360, 363–370.
Sato, K, Ohuchi, A, Sook, SH, Toyomizu, M, Akiba, Y 2003. Changes in mRNA expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol 7 alpha-hydroxylase in chickens. Biochimica Biophysica Acta 1630, 96–102.
Scandinavian Simvastatin Survival Study 1994. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344, 1383–1389.
Shepherd, J, Cobbe, SM, Ford, I, Isles, CG, Lorimer, AR, MacFarlane, PW, McKillop, JH, Packard, CJ 1995. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. The New England Journal of Medicine 333, 1301–1307.
Simonet, WS, Ness, GC 1988. Transcriptional and post-transcriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-CoA reductase by thyroid hormones. The Journal of Biological Chemistry 263, 12448–12453.
Stanton, HC, Mersmann, HJ 1986. Swine in cardiovascular research. CRC Press, Boca Raton,FL, USA.
Sundaresan, S, Yang-Feng, TL, Francke, U 1989. Genes for HMG-CoA reductase and serotonin 1a receptor are on mouse chromosome 13. Somatic Cell and Molecular Genetics 15, 465–469.
Tabas, I 2002. Cholesterol in health and disease. The Journal of Clinical Investigation 110, 583–590.
The Lipid Research Clinics Coronary Primary Prevention Trial results (LRC-CPPT) 1984. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. The Journal of American Medical Association 251, 365–374.
Tobert, JA 2003. Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors. Nature Reviews Drug Discovery 2, 517–526.
Use Bulletin 2 1997. ABI Prism 7700 Sequence Detection System. The Perkin Elmer Corporation, P/N 4303859 Rev. A, Stock No. 777802-001. Foster City, CA.
Van, TA, Van, GT, Scheek, LM, Groener, JE, Sassen, LM, Lamers, JM, Verdouw, PD 1991. Lipoprotein structure and metabolism during progression and regression of atherosclerosis in pigs fed with fish oil-derived fatty acids. Advances in Experimental Medicine and Biology 285, 417–421.
Wang, XF 2006. Molecular cloning, expression analysis, chromosome mapping and polymorphism analysis of porcine HMGR gene. PhD, China Agricultural University.