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Article contents

Colostrum production in ewes: a review of regulation mechanisms and of energy supply

Published online by Cambridge University Press:  05 January 2015

G. E. Banchero*
Affiliation:
National Institute of Agricultural Research (INIA), Ruta 50 km 12, La Estanzuela 70000, Uruguay
J. T. B. Milton
Affiliation:
School of Animal Biology, UWA Institute of Agriculture, The University of Western Australia, Crawley 6009, Australia
D. R. Lindsay
Affiliation:
School of Animal Biology, UWA Institute of Agriculture, The University of Western Australia, Crawley 6009, Australia
G. B. Martin
Affiliation:
School of Animal Biology, UWA Institute of Agriculture, The University of Western Australia, Crawley 6009, Australia Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, OX3 9DU, UK
G. Quintans
Affiliation:
National Institute of Agricultural Research (INIA), Ruta 50 km 12, La Estanzuela 70000, Uruguay
*Corresponding
E-mail: gbanchero@inia.org.uy
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Abstract

In sheep production systems based on extensive grazing, neonatal mortality often reaches 15% to 20% of lambs born, and the mortality rate can be doubled in the case of multiple births. An important contributing factor is the nutrition of the mother because it affects the amount of colostrum available at birth. Ewes carrying multiple lambs have higher energy requirements than ewes carrying a single lamb and this problem is compounded by limitations to voluntary feed intake as the gravid uterus compresses the rumen. This combination of factors means that the nutritional requirements of the ewe carrying multiple lambs can rarely be met by the supply of pasture alone. This problem can overcome by supplementation with energy during the last week of pregnancy, a treatment that increases colostrum production and also reduces colostrum viscosity, making it easier for the neonatal lamb to suck. In addition, litter size and nutrition both accelerate the decline in concentration of circulating progesterone that, in turn, triggers the onsets of both birth and lactogenesis, and thus ensures the synchrony of these two events. Furthermore, the presence of colostrum in the gut of the lamb increases its ability to recognize its mother, and thus improves mother–young bonding. Most cereal grains that are rich in energy in the form of starch, when used as supplements in late pregnancy will increase colostrum production by 90% to 185% above control (unsupplemented) values. Variation among types of cereal grain in the response they induce may be due to differences in the amount of starch digested post-ruminally. As a percentage of grain dry matter intake, the amount of starch entering the lower digestive tract is 14% for maize, 8.5% for barley and 2% for oats. Supplements of high quality protein from legumes and oleiferous seeds can also increase colostrum production but they are less effective than cereal grains. In conclusion, short-term supplementation before parturition, particularly with energy-rich concentrates, can improve colostrum production, help meet the energy and immunological requirements for new-born lambs, and improve lamb survival.

Type
Review Article
Copyright
© The Animal Consortium 2015 

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References

Aiello, SE 1998. Serum biochemical reference range. In The merck veterinary manual (ed. SE Aiello), pp. 21922193. Merck & Co. Inc, Whitehouse Station, Philadelphia,USA.Google Scholar
Banchero, GE, Quintans, G, Lindsay, DR and Milton, JTB 2009. A pre-partum lift in ewe nutrition from a high-energy lick or maize or by grazing Lotus uliginosus pasture, increases colostrum production and lamb survival. Animal 3, 11831188.CrossRefGoogle ScholarPubMed
Banchero, GE, Quintans, G, Martin, GB, Lindsay, DR and Milton, JTB 2004a. Nutrition and colostrum production in sheep. 1. Metabolic and hormonal responses to a high-energy supplement in the final stages of pregnancy. Reproduction, Fertility and Development 16, 633643.CrossRefGoogle ScholarPubMed
Banchero, GE, Quintans, G, Martin, GB, Lindsay, DR and Milton, JTB 2004b. Nutrition and colostrum production in sheep. 2. Metabolic and hormonal responses to different energy sources in the final stages of pregnancy. Reproduction, Fertility and Development 16, 645653.CrossRefGoogle ScholarPubMed
Banchero, GE, Quintans, G, Vazquez, A, Gigena, F, La Manna, A, Lindsay, DR and Milton, JTB 2007. Effect of supplementation of ewes with barley or maize during the last week of pregnancy on colostrum production. Animal 1, 625630.CrossRefGoogle ScholarPubMed
Barry, TN and Manley, TR 1985. Glucose and protein metabolism during late pregnancy in triplet-bearing ewes given fresh forages ad lib . British Journal of Nutrition 54, 521533.CrossRefGoogle ScholarPubMed
Bedford, CA, Harrison, FA and Heap, RB 1974. Splanchnic, uterine, ovarian and adrenal uptake of progesterone and 20α-dihydroprogesterone in the pregnant and non-pregnant sheep. Journal of Endocrinology 62, 277290.CrossRefGoogle Scholar
Bermúdez, R and Ayala, W 2005. Forage production in a native pasture of the Lomadas del Este, Uruguay. Technical Bulletin INIA 151, 3339.Google Scholar
Brockhus, MA, Nunan, K and Parr, RA 1988. A relationship between nutrition and progesterone at parturition and the implication for lamb survival. Australian Society for Reproductive Biology 20, 62.Google Scholar
Burrin, DG, Ferrell, CL, Eisemann, JH, Britton, RA and Nienaber, JA 1989. Effect of level of nutrition on splanchnic blood flow and oxygen consumption in sheep. British Journal of Nutrition 62, 2334.CrossRefGoogle Scholar
Emmanuel, B and Edjtehadi, M 1981. Glucose biokinetics in normal and urea-treated sheep (Ovis aries). Comparative Biochemistry and Physiology 68, 555560.Google Scholar
Fierro, S, Olivera-Muzante, J, Gil, J, Antognazza, J, Durán, J, Sánchez, S and Banchero, G 2012. Birth traits, colostrum and vigor of lambs born to single or twin bearing ewes supplemented or not in late gestation (in Spanish). Veterinaria 48 (suppl. 1), 171.Google Scholar
Freetly, HC and Ferrell, CL 1994. Kinetics of splanchnic progesterone metabolism in ewes fed two levels of nutrition. Journal of Animal Science 72, 21072112.CrossRefGoogle ScholarPubMed
Greaney, KB, Reynolds, GW, Ulyatt, MJ, Mackenzie, DDS and Harris, PM 1996. The metabolic cost of hepatic ammonia detoxification. Proceedings of the New Zealand Society of Animal Production 56, pp. 130–132.Google Scholar
Hall, DG, Holst, PJ and Shutt, DA 1992a. The effect of nutritional supplements in late pregnancy on ewe colostrum production plasma progesterone ad IGF-I concentrations. Australian Journal of Agricultural Research 43, 325337.CrossRefGoogle Scholar
Hall, DG, Piper, LR, Egan, AR and Bindon, BM 1992b. Lamb and milk production from Booroola ewes supplemented in late pregnancy. Australian Journal of Experimental Agriculture 32, 587593.CrossRefGoogle Scholar
Hartmann, PE 1973. Changes in the composition and yield of the mammary secretion of cows during the initiation of lactation. Journal of Endocrinology 59, 231247.CrossRefGoogle ScholarPubMed
Hartmann, PE, Trevethan, P and Shelton, JN 1973. Progesterone and oestrogen and the initiation of lactation in ewes. Journal of Endocrinology 59, 249259.CrossRefGoogle ScholarPubMed
Hawken, PAR, Williman, M, Milton, J, Kelly, R, Nowak, R and Blache, D 2012. Nutritional supplementation during the last week of gestation increased the volume and reduced the viscosity of colostrum produced by twin bearing ewes selected for nervous temperament. Small Ruminant Research 105, 308314.CrossRefGoogle Scholar
Hibbit, KG 1988. Effect of protein on the health of dairy cows. In Recent developments in ruminant nutrition 2 (ed. W Haresign and DJA Cole), pp. 184195. Butterworths, London, England.CrossRefGoogle Scholar
Holst, PJ, Hall, DG and Allan, CJ 1996. Ewe colostrum and subsequent lamb suckling behaviour. Australian Journal of Experimental Agriculture 36, 637640.CrossRefGoogle Scholar
Holst, PJ, Hall, DJ and Lee, GJ 2005. Colostrum production and hormone responses of parturient ewes fed varying amounts and types of supplement. Australian Journal of Experimental Agriculture 45, 12311238.CrossRefGoogle Scholar
Hungerford, TG 1990. Ammonia toxicity. In Diseases of livestock, pp. 199200. McGraw-Hill Book Company Australia Pty Limited, Sydney, Australia.Google Scholar
Huntington, GB 1997. Starch utilization by ruminants: from basis to bunk. Journal of Animal Science 75, 852867.CrossRefGoogle Scholar
Hurtard, C, Lemosquet, S and Rulquin, H 2000. Effect of graded duodenal infusions of glucose on yield and composition of milk from dairy cows. 2. Diets based on grass silage. Journal of Dairy Science 83, 29522962.CrossRefGoogle Scholar
Knowlton, KF, Glenn, BP and Erdman, RA 1998. Performance, ruminal fermentation, and site of starch digestion in early lactation cows fed corn grain harvested and processed differently. Journal of Dairy Science 81, 19721984.CrossRefGoogle ScholarPubMed
Knowlton, KF, Erdman, RA and Glenn, BP 1999. Corn processing influences more than starch digestion. Feedstuffs 71, 1113.Google Scholar
Kuhn, NJ 1983. The biochemistry of lactogenesis. In Biochemistry of lactation (ed. TB Mephan), pp. 351379. Elsevier Science Publishers BV, Amsterdam, The Netherlands.Google Scholar
Landau, S, Nitsan, Z, Zoref, Z and Madar, Z 1992. The influence of processing corn grain on glucose metabolism in ewes. Reproduction, Nutrition, Development 32, 231240.CrossRefGoogle ScholarPubMed
Linzell, JL 1967. The effect of infusions of glucose, acetate and amino acids on hourly milk yield in fed, fasted and insulin-treated goats. Journal of Physiology 190, 347357.CrossRefGoogle ScholarPubMed
Linzell, JL 1974. Mammary blood flow and methods of identifying and measuring precursors of milk. In Lactation – a comprehensive treatise (ed. BL Larson and VR Smith), vol 1, pp. 143225. Academic Press, New York, USA.Google Scholar
Lobley, GE, Connell, A, Lomax, MA, Brown, DS, Milne, E, Calder, AG and Farningham, DAH 1995. Hepatic detoxification of ammonia in the ovine liver: possible consequences for amino acid catabolism. British Journal of Nutrition 73, 667685.CrossRefGoogle ScholarPubMed
Ministry of Agriculture, Fisheries and Food (MAFF) 1975. Energy allowances and feeding systems for ruminants (Technical Bulletin 33. Ministry of Agriculture, Fisheries and Food, London. 79pp.Google Scholar
Maltier, JP, Legrand, C and Breuiller, M 1993. Parturition. In: Reproduction in mammals and man (ed. C Thibault, MC Levasseur and RHF Hunter), pp. 481501. Ellipses, Paris, France.Google Scholar
McCance, I and Alexander, G 1959. The onset of lactation in the Merino ewe and its modification by nutritional factors. Australian Journal of Agricultural Research 10, 699719.CrossRefGoogle Scholar
McCracken, JA 1964. Progesterone in the body fat of the dairy cow. Journal of Endocrinology 28, 339340.CrossRefGoogle ScholarPubMed
McDonald, P, Edwards, RA and Greenhalgh, JFD 1988. Cereal grains and cereal by-products. In Animal nutrition (ed. P McDonald, RA Edwards and JFD Greenhalgh), pp. 438454. Longman Scientific & Technical, Harlow, Essex, UK; John Wiley & Son, New York, USA.Google Scholar
McNeill, DM, Murphy, PM and Purvis, IW 1988. Lactogenesis and colostrum production in ewes. Proceedings of the Australian Society of Animal Production 17, 437.Google Scholar
McNeill, DM, Murphy, PM and Lindsay, DR 1998. Blood lactose v. milk lactose as a monitor of lactogenesis and colostrum production in Merino ewes. Australian Journal of Agricultural Research 49, 581587.CrossRefGoogle Scholar
Mellor, DJ 1988. Integration of perinatal events, pathophysiological changes and consequences for the newborn lamb. British Veterinary Journal 144, 552569.CrossRefGoogle ScholarPubMed
Mellor, DJ and Murray, L 1985a. Effects of maternal nutrition on the availability of energy in the body reserves of fetuses at term and in colostrum from Scottish Blackface ewes with twin lambs. Research in Veterinary Science 39, 235240.Google ScholarPubMed
Mellor, DJ and Murray, L 1985b. Effects of maternal nutrition on udder development during late pregnancy and on colostrum production in Scottish Blackface ewes with twin lambs. Research in Veterinary Science 39, 230234.Google ScholarPubMed
Mellor, DJ and Cockburn, F 1986. A comparison of energy metabolism in the new-born infant, piglet and lamb. Quarterly Journal of Experimental Physiology 71, 361379.CrossRefGoogle ScholarPubMed
Mellor, DJ and Murray, L 1986. Making the most of colostrum at lambing. Veterinary Record 118, 351353.CrossRefGoogle ScholarPubMed
Mellor, DJ, Flint, DJ, Vernon, RG and Forsyth, IA 1987. Relationships between plasma hormone concentrations, udder development and the production of early mammary secretions in twin-bearing ewes on different planes of nutrition. Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 72, 345356.CrossRefGoogle ScholarPubMed
Meyer, AM, Reed, JJ, Neville, TL, Thorson, JF, Maddock-Carlin, KR, Taylor, JB, Reynolds, LP, Redmer, DA, Luther, JS, Hammer, CJ, Vonnahme, KA and Caton, JS 2011. Nutritional plane and selenium supply during gestation affect yield and nutrient composition of colostrum and milk in primiparous ewes Journal of Animal Science 89, 16271639.CrossRefGoogle ScholarPubMed
Murphy, PM 1999. Maternal behaviour and rearing ability of Merino ewes can be improved by strategic feed supplementation during late pregnancy and selection for calm temperament. PhD Thesis, The University of Western Australia, Australia.Google Scholar
Murphy, PM, McNeill, DM, Fisher, JS and Lindsay, DR 1996. Strategic feeding of Merino ewes in late pregnancy to increase colostrum production. Animal Production in Australia, Proceedings of the Australian Society of Animal Production, 21, 227–230.Google Scholar
Nocek, JE and Tamminga, S 1991. Site of digestion of starch in the gastrointestinal tract of dairy cows and its effect on milk yield and composition. Journal of Dairy Science 74, 35983629.CrossRefGoogle ScholarPubMed
National Research Council 1985. Nutrient requirements of sheep. National Academy Press, Washington, USA. 99pp.Google ScholarPubMed
Ocak, N, Cam, MA and Kuran, M 2005. The effect of high dietary protein levels during late gestation on colostrum yield and lamb survival rate in singleton-bearing ewes. Small Ruminant Research 56, 8994.CrossRefGoogle Scholar
Oddy, VH and Holst, PJ 1991. Maternal-foetal adaptation to mid pregnancy feed restriction in single-bearing ewes. Australian Journal of Agricultural Research 42, 969978.CrossRefGoogle Scholar
Parr, RA 1992. Nutrition-progesterone interactions during early pregnancy in sheep. Reproduction, Fertility and Development 4, 297300.CrossRefGoogle Scholar
Parr, RA, Davis, IF, Miles, MA and Squires, TJ 1993a. Feed intake affects metabolic clearance rate of progesterone in sheep. Research in Veterinary Science 55, 306310.CrossRefGoogle Scholar
Parr, RA, Davis, IF, Miles, MA and Squires, TJ 1993b. Liver blood flow and metabolic clearance rate of progesterone in sheep. Research in Veterinary Science 55, 311316.CrossRefGoogle Scholar
Pattinson, SE, Davies, DAR and Winter, AC 1995. Changes in the secretion rate and production of colostrum by ewes over the first 24 h post partum. Animal Science 61, 6368.CrossRefGoogle Scholar
Peart, JN 1967. The effect of different levels of nutrition during late pregnancy on the subsequent milk production of Blackface ewes and on the growth of their lambs. Journal of Agricultural Science (Cambridge) 68, 365371.CrossRefGoogle Scholar
Rabaza, A 2012. Effect of prepartum supplementation of twin bearing Polwarth ewes on colostrum quality and quantity and lamb survival (in Spanish). Degree thesis, Faculty of Veterinary, Montevideo, Uruguay, 191pp.Google Scholar
Rigout, S, Lemosquet, JE, van Eys, JE and Blum, JW 2002. Duodenal glucose increases glucose fluxes and lactose synthesis in grass silage-fed dairy cows. Journal of Dairy Science 85, 595606.CrossRefGoogle ScholarPubMed
Robinson, JJ, Rooke, JA and McEvoy, TG 2002. Nutrition for conception and pregnancy. In Sheep nutrition (ed. M Freer and H Dove), pp. 189211. CABI Publishing in Association with CSIRO Publishing, Canberra, Australia.CrossRefGoogle Scholar
Roeder, BL, Thomas, VM, Kott, RW, Hatfield, PG and Burgess, D 2000. Effect of short term, prepartum feeding of level and type of protein on ewe performance and colostrum accumulation. Sheep and Goat Research Journal 16, 15.Google Scholar
Sangsritavong, S, Combs, DK, Sartori, R, Armentano, LE and Wiltbank, MC 2002. High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17beta in dairy cattle. Journal of Dairy Science 85, 28312842.CrossRefGoogle ScholarPubMed
Shubber, AH, Doxey, DL, Black, WJM and FitzSimons, J 1979. Colostrum production by ewes and the amounts ingested by lambs. Research in Veterinary Science 27, 280282.Google ScholarPubMed
Swanson, TJ, Hammer, CJ, Luther, JS, Carlson, DB, Taylor, JB, Redmer, DA, Neville, TL, Reynolds, LP, Caton, JS and Vonnahme, KA 2008. Effects of gestational plane of nutrition and selenium supplementation on mammary development and colostrum quality in pregnant ewe lambs. Journal of Animal Science 86, 24152423.CrossRefGoogle ScholarPubMed
Tamminga, S, Van Vuuren, AM, Van der Koelen, J, Ketelaar, RS, and Van der Togt, PL 1990. Ruminal behaviour of structural carbohydrates, non-structural carbohydrates and crude protein from concentrate ingredients in dairy cows. Nether. Journal of Agricultural Science 38, 513526.Google Scholar
Taniguchi, K, Sunada, Y and Obistu, T 1993. Starch digestion in the small intestine of sheep sustained by intra-gastric infusion without protein supply. Animal Science Technology (Japan) 64, 892902.Google Scholar
Thomas, DL, Thomford, PJ, Crickman, JG, Cobb, AR and Dziuk, PJ 1987. Effects of plane of nutrition and phenobarbital during the pre-mating period on reproduction in ewes fed differentially during the summer and mated in the fall. Journal of Animal Science 64, 11441152.CrossRefGoogle ScholarPubMed
Thomford, PJ and Dziuk, PJ 1986. The influence of dose of phenobarbital and interval to measurement on concentration of liver enzymes in barrows and gilts. Journal of Animal Science 63, 11841190.CrossRefGoogle ScholarPubMed
Treacher, TT 1970. Effects of nutrition in late pregnancy on subsequent milk production in ewes. Animal Production 12, 2336.CrossRefGoogle Scholar
Tygesen, MP, Nielsen, MO, Norgaard, P, Ranvig, H, Harrison, AP and Tauson, AH 2008. Late gestational nutrient restriction: effects on ewes’ metabolic and homeorhetic adaptation, consequences for lamb birth weight and lactation performance. Archives of Animal Nutrition 62, 4459.CrossRefGoogle ScholarPubMed
Tyrrell, HF, Moe, PW and Flatt, WP 1970. Influence of excess protein intake on energy metabolism of the dairy cow. Proceedings of the 5th Symposium on Energy Metabolism, European Association of Animal Production, Vitznau, Switzerland, pp. 69–72.Google Scholar
Wallace, JM, Bourke, DA, Da Silva, P and Aitken, RP 2001. Nutrient partitioning during adolescent pregnancy. Reproduction 122, 347357.CrossRefGoogle ScholarPubMed
Weston, RH 1988. Factors limiting the intake of feed by sheep. 11. The effect of pregnancy and early lactation on the digestion of a medium-quality roughage. Australian Journal of Agricultural Research 39, 659669.CrossRefGoogle Scholar
Wieghart, M, Slepetis, R, Elliot, JM and Smith, DF 1986. Glucose absorption and hepatic gluconeogenesis in dairy cows fed diets varying in forage content. Journal of Nutrition 116, 839850.Google ScholarPubMed

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