Skip to main content Accessibility help
  • Print publication year: 2014
  • Online publication date: August 2014

Chapter 8 - Catamenial epilepsy


1. Foldvary-Schaefer N, Harden C, Herzog A, et al. Hormones and seizures. Cleve Clin J Med 2004; 71(Suppl 2):S11–S8.
2. Reddy DS. Role of neurosteroids in catamenial epilepsy. Epilepsy Res 2004; 62(2–3):99–118.
3. Veliskova J, De Jesus G, Kaur R, et al. Females, their estrogens, and seizures. Epilepsia 2010; 51(Suppl 3):141–4.
4. Woolley CS. Estradiol facilitates kainic acid-induced, but not flurothyl-induced, behavioral seizure activity in adult female rats. Epilepsia 2000; 41(5):510–5.
5. Hom, AC and Butterbough, GG. Estrogen alters the acquisition of seizures kindled by repeated amygdala stimulation or pentylenetetrazol administration in ovariectomized female rats. Epilepsia 1986; 27:103–8.
6. Backstrom T. Epileptic seizures in women related to plasma estrogen and progesterone during the menstrual cycle. Acta Neurol Scand 1976; 54(4):321–47.
7. Woolley CS and McEwen BS. Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. Neurosci 1994; 14(12):7680–7.
8. Herzog AG. Hormonal therapies: progesterone. Neurotherapeutic 2009; 6(2):383–91.
9. Frye CA. Effects and mechanisms of progestogens and androgens in ictal activity. Epilepsia 2010; 51(Suppl 3):135–40.
10. Ansell B and Clarke E. Epilepsy and menstruation: the role of water retention. Lancet 1956; 271(6955):1232–5.
11. De Wildt SN KG, Leeder JS and Van Den Anker JN. Glucuronidation in humans. Pharmacogenetic and developmental aspects. Clin Pharmacokinet 1999; 36(6):439–52.
12. Rosciszewska D, Buntner B, Guz I, et al. Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual cycle in women with epilepsy. J Neurol Neurosurg Psychiatry 1986; 49(1):47–51.
13. Herkes G and Eadie, MJ. Possible roles for frequent salivary AED monitoring in the management of epilepsy. Epilepsy Res Suppl 1990; 6:146–54.
14. Herzog AG, Blum AS, Farina EL, et al. Valproate and lamotrigine level variation with menstrual cycle phase and oral contraceptive use. Neurology 2009; 72(10):911–4.
15. Herzog AG, Klein P and Ransil BJ. Three patterns of catamenial epilepsy. Epilepsia 1997; 38(10):1082–8.
16. Quigg M, Smithson SD, Fowler KM, et al. Laterality and location influence catamenial seizure expression in women with partial epilepsy. Neurology 2009; 73(3):223–7.
17. Herzog AG, Fowler KM, Sperling MR, et al. Variation of seizure frequency with ovulatory status of menstrual cycles. Epilepsia 2011; 52(10):1843–8.
18. Speroff L, Glass RH and Kase NG. Clinical gynecologic endocrinology and infertility. Philadelphia, PA: Lippincott Williams & Wilkins, 1999.
19. Feely M, Calvert R and Gibson J. Clobazam in catamenial epilepsy. A model for evaluating anticonvulsants. Lancet 1982; 2(8289):71–3.
20. Feely M and Gibson J. Intermittent clobazam for catamenial epilepsy: tolerance avoided. J Neurol Neurosurg Psychiatry 1984; 47(12):1279–82.
21. Krishnamurthy BS and Schomer DL. Weekly fluctuation and adjustment of antiepileptic drugs to treat catamenial seizures. Epilepsia 1998; 39(Suppl 6):179.
22. Anderson RE, Howard RA and Woodbury DM. Correlation between effects of acute acetazolamide administration to mice on electroshock seizure threshold and maximal electroshock seizure pattern, and on carbonic anhydrase activity in subcellular fractions of brain. Epilepsia 1986; 27(5):504–9.
23. Lim LL, Foldvary N, Mascha E, et al. Acetazolamide in women with catamenial epilepsy. Epilepsia 2001; 42(6):746–9.
24. Dana-Haeri J and Richens A. Effect of norethisterone on seizures associated with menstruation. Epilepsia 1983; 24(3):377–81.
25. Mattson RH, Cramer JA, Caldwell BV, et al. Treatment of seizures with medroxyprogesterone acetate: preliminary report. Neurology 1984; 34(9):1255–8.
26. Herzog AG. Progesterone therapy in women with epilepsy: a 3-year follow-up. Neurology 1999; 52(9):1917–8.
27. Herzog AG. Progesterone therapy in women with complex partial and secondary generalized seizures. Neurology 1995; 45(9):1660–2.
28. Herzog A. Intermittent progesterone therapy of partial complex seizures in women with menstrual disorders. Neurology 1986; 36:1607–10.
29. Herzog A, Fowler KM, Smithson SD, et al. For the Progesterone Trial Study Group. Progesterone vs placebo therapy for women with epilepsy: a randomized clinical trial. Neurology 2012; 78(24):1959–66.
30. McAuley J, Moore JL, Reeves AL, et al. A pilot study of the neurosteroid ganaxolone in catamenial epilepsy: clinical experience in two patients. Epilepsia 2001; 42:85.
31. Herzog A. Clomiphene therapy in epileptic women with menstrual disorders. Neurology 1988; 38:432–4.
32. Bauer J, Wildt L, Flugel D, et al. The effect of a synthetic GnRH analogue on catamenial epilepsy: a study in ten patients. J Neurol Neurosurg Psychiatry 1992; 239:284–6.
33. Ichida M, Gomi A, Hiranouchi N, et al. A case of cerebral endometriosis causing catamenial epilepsy. Neurology 1993; 43(12):2708–9.
34. Vilos GA, Hollett-Caines J, Abu-Rafea B, et al. Resolution of catamenial epilepsy after goserelin therapy and oophorectomy: case report of presumed cerebral endometriosis. J Minim Invasive Gynecol 2011; 18(1):128–30.