Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-17T19:29:28.118Z Has data issue: false hasContentIssue false

Chapter 11 - Cerebral Small-Vessel Disease

from Section 3 - Diagnostics and Syndromes

Published online by Cambridge University Press:  16 May 2019

By
Wolf-Dieter Heiss ,
Michael Brainin  and
Alina Schwarz
Edited by
Michael Brainin  and
Wolf-Dieter Heiss
Michael Brainin
Affiliation:
Donau-Universität Krems, Austria
Wolf-Dieter Heiss
Affiliation:
Universität zu Köln
Get access
Type
Chapter
Information
Textbook of Stroke Medicine , pp. 202 - 212
Publisher: Cambridge University Press
Print publication year: 2019

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Banerjee, G, Wilson, D, Jäger, HR, Werring, DJ. Novel imaging techniques in cerebral small vessel diseases and vascular cognitive impairment. Biochim Biophys Acta 2016; 1862: 926–38.Google Scholar
Rosenberg, GA, Wallin, A, Wardlaw, JM, et al. Consensus statement for diagnosis of subcortical small vessel disease. J Cereb Blood Flow Metab 2016; 36: 6–25.CrossRefGoogle ScholarPubMed
Wardlaw, JM, Smith, EE, Biessels, GJ, et al. STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1): neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822–38.Google Scholar
Pantoni, L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689–701.CrossRefGoogle ScholarPubMed
Jellinger, KA. The enigma of vascular cognitive disorder and vascular dementia. Acta Neuropathol 2007; 113: 349–88.Google Scholar
Hachinski, VC, Iliff, LD, Zilhka, E, et al. Cerebral blood flow in dementia. Arch Neurol 1975; 32: 632–7.Google Scholar
Guermazi, A, Miaux, Y, Rovira-Cañellas, A, et al. Neuroradiological findings in vascular dementia. Neuroradiol 2007; 49: 1–22.CrossRefGoogle ScholarPubMed
Pohjasvaara, T, Mäntylä, R, Salonen, O, et al. MRI correlates of dementia after first clinical ischemic stroke. J Neurol Sci 2000; 181: 111–17.Google Scholar
Román, GC, Erkinjuntti, T, Wallin, A, Pantoni, L, Chui, HC. Subcortical ischaemic vascular dementia. Lancet Neurol 2002; 1: 426–36.CrossRefGoogle ScholarPubMed
Blair, GW, Hernandez, MV, Thrippleton, MJ, Doubal, FN, Wardlaw, JM. Advanced neuroimaging of cerebral small vessel disease. Curr Treat Options Cardiovasc Med 2017; 19: 56.CrossRefGoogle ScholarPubMed
Carrera, E, Bogousslavsky, J. The thalamus and behavior: effects of anatomically distinct strokes. Neurol 2006; 66: 1817–23.Google Scholar
Wattjes, MP, Henneman, WJP, van der Flier, WM, et al. Diagnostic imaging of patients in a memory clinic: comparison of MR imaging and 64–detector row CT. Radiol 2009; 253: 174–83.Google Scholar
Wahlund, LO, Barkhof, F, Fazekas, F, et al. European Task Force on Age-Related White Matter Changes: a new rating scale for age-related white matter changes applicable to MRI and CT. Stroke 2001; 32: 1318–22.Google Scholar
Vitali, P, Migliaccio, R, Agosta, F, Rosen, H, Geschwind, M. Neuroimaging in dementia. Semin Neurol 2008; 28: 467–83.CrossRefGoogle ScholarPubMed
Brainin, M, Tuomilehto, J, Heiss, W-D, et al. Post Stroke Cognition Study Group, post-stroke cognitive decline: an update and perspectives for clinical research. Eur J Neurol 2015; 22: 229–38, e13–16.Google Scholar
Ding, J, Sigurðsson, S, Jónsson, PV, et al. Large perivascular spaces visible on magnetic resonance imaging, cerebral small vessel disease progression, and risk of dementia. JAMA 2017; 74: 1105.Google Scholar
Hachinski, VC, Potter, P, Merskey, H. Leuko-araiosis. Arch Neurol 1987; 44: 21–3.Google Scholar
Shi, Y, Thrippleton, MJ, Makin, SD, et al. Cerebral blood flow in small vessel disease: a systematic review and meta-analysis. J Cereb Blood Flow Metab 2016; 36: 1653–67.CrossRefGoogle ScholarPubMed
De Guio, F, Jouvent, E, Biessels, GJ, et al. Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease. J Cereb Blood Flow Metab 2016; 36: 1319–37.Google Scholar
Benjamin, P, Viessmann, O, MacKinnon, AD, Jezzard, P, Markus, HS. 7 Tesla MRI in cerebral small vessel disease. Int J Stroke 2015; 10: 659–64.CrossRefGoogle ScholarPubMed
Boone, KB, Miller, BL, Lesser, IM, et al. Neuropsychological correlates of white-matter lesions in healthy elderly subjects: a threshold effect. Arch Neurol 1992; 49: 549–54.Google Scholar
van Straaten, ECW, Scheltens, P, Knol, DL, et al. Operational definitions for the NINDS-AIREN criteria for vascular dementia: an interobserver study. Stroke 2003; 34: 1907–12.Google Scholar
Arba, F, Quinn, T, Hankey, GJ, et al. Cerebral small vessel disease, medial temporal lobe atrophy and cognitive status in patients with ischaemic stroke and transient ischaemic attack. Eur J Neurol 2017; 24: 276–82.CrossRefGoogle ScholarPubMed
Román, GC. Senile dementia of the Binswanger type: a vascular form of dementia in the elderly. JAMA 1987; 258: 1782–8.Google Scholar
Cordonnier, C, van der Flier, WM, Sluimer, JD, et al. Prevalence and severity of microbleeds in a memory clinic setting. Neurology 2006; 66: 1356–60.CrossRefGoogle Scholar
Koennecke, H-C. Cerebral microbleeds on MRI: prevalence, associations, and potential clinical implications. Neurology 2006; 66: 165–71.Google Scholar
Cordonnier, C, Al-Shahi Salman, R, Wardlaw, J. Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting. Brain 2007; 130: 1988–2003.Google Scholar
Heiss, W-D, Zimmermann-Meinzingen, S. PET imaging in the differential diagnosis of vascular dementia. J Neurol Sci 2012; 322: 268–273.Google Scholar
Benson, DF, Kuhl, DE, Hawkins, RA, et al. The fluorodeoxyglucose 18F scan in Alzheimer's disease and multi-infarct dementia. Arch Neurol 1983; 40: 711–14.Google Scholar
Mielke, R, Herholz, K, Grond, M, Kessler, J, Heiss, WD. Severity of vascular dementia is related to volume of metabolically impaired tissue. Arch Neurol 1992; 49: 909–13.CrossRefGoogle ScholarPubMed
Herholz, K. PET studies in dementia. Ann Nucl Med 2003; 17: 79–89.Google Scholar
Herholz, K, Salmon, E, Perani, D, et al. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage 2002; 17: 302–16.CrossRefGoogle ScholarPubMed
Bohnen, NI, Djang, DSW, Herholz, K, Anzai, Y, Minoshima, S. Effectiveness and safety of 18F-FDG PET in the evaluation of dementia: a review of the recent literature. J Nucl Med 2012; 53: 59–71.CrossRefGoogle ScholarPubMed
Herholz, K, Weisenbach, S, Kalbe, E, Diederich, NJ, Heiss, W-D. Cerebral acetylcholine esterase activity in mild cognitive impairment. Neuroreport 2005; 16: 1431–4.CrossRefGoogle ScholarPubMed
Hilker, R, Thomas, AV, Klein, JC, et al. Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology 2005; 65: 1716–22.CrossRefGoogle ScholarPubMed
Braak, H, Braak, E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239–59.Google Scholar
Klunk, WE, Engler, H, Nordberg, A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 2004; 55: 306–19.CrossRefGoogle ScholarPubMed
Villemagne, VL, Mulligan, RS, Pejoska, S, et al. Comparison of 11C-PiB and 18F-florbetaben for Aβ imaging in ageing and Alzheimer's disease. Eur J Nucl Med Mol Imaging 2012; 39: 983–9.Google Scholar
Aizenstein, HJ, Nebes, RD, Saxton, JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol 2008; 65: 1509.CrossRefGoogle ScholarPubMed
Herholz, K, Ebmeier, K. Clinical amyloid imaging in Alzheimer's disease. Lancet Neurol 2011; 10: 667–70.Google Scholar
Yotter, RA, Doshi, J, Clark, V, et al. Memory decline shows stronger associations with estimated spatial patterns of amyloid deposition progression than total amyloid burden. Neurobiol Aging 2013; 34: 2835–42.CrossRefGoogle ScholarPubMed
Thiel, A, Cechetto, DF, Heiss, W-D, Hachinski, V, Whitehead, SN. Amyloid burden, neuroinflammation, and links to cognitive decline after ischemic stroke. Stroke 2014; 45: 2825–9.CrossRefGoogle ScholarPubMed
Maruyama, M, Shimada, H, Suhara, T, et al. Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls. Neuron 2013; 79: 1094–108.Google Scholar
Small, GW, Bookheimer, SY, Thompson, PM, et al. Current and future uses of neuroimaging for cognitively impaired patients. Lancet Neurol 2008; 7: 161–72.CrossRefGoogle ScholarPubMed
Spillantini, MG, Goedert, M. Tau pathology and neurodegeneration. Lancet Neurol 2013; 12: 609–22.Google Scholar
Schöll, M, Lockhart, SN, Schonhaut, DR, et al. PET imaging of tau deposition in the aging human brain. Neuron 2016; 89: 971–82.CrossRefGoogle ScholarPubMed
Sepulcre, J, Schultz, AP, Sabuncu, M, et al. In vivo tau, amyloid, and gray matter profiles in the aging brain. J Neurosci 2016; 36: 7364–74.Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×