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  • Cited by 4
  • Print publication year: 2010
  • Online publication date: May 2010

11c - Neurobehavioral aspects of traumatic brain injury sustained in adulthood

from Section II - Disorders

Summary

Introduction

Traumatic brain injury (TBI) is an important public health issue in the USA, with estimates of over 1.5 million new cases a year, most commonly due to motor vehicle accidents and falls [1]. TBI ranges in severity from mild to severe and results in some disturbance in cognitive, behavioral, emotional, or physical functioning. Often the effects of TBI are not physically observable to others, and thus are not well understood or appreciated by the general public. For persons with mild injuries, these effects may be first recognized, diagnosed, and treated by neuropsychologists. Thus, it is imperative that neuropsychologists have a good understanding of the short- and long-term cognitive, neurobehavioral, and psychosocial effects of TBI and how these effects change over the course of TBI recovery.

Although no particular demographic group is biologically predisposed to brain injury, certain groups are at higher risk. In adults, rates for TBI peak between the ages of 15 and 24 years and for persons older than 64 [2]. Other than for the very young or the very old, TBI rates are universally higher for men than women [3]. Other risk factors for brain injury include alcohol consumption [4], prior brain injury [5], and low socioeconomic status [6]. TBIs related to sports and recreation activities are receiving more attention, with an estimated 300,000 sports-related injuries with loss of consciousness each year [7].

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References
Rutland-Brown, W, Langlois, JA, Thomas, KE, et al. Incidence of traumatic brain injury in the United States, 2003. J Head Trauma Rehabil 2006;21:544–8.
Kraus, JF, Chu, LD. Epidemiology. In Silver, JM, McAllister, TW, Yudofsky, SC, eds. Textbook of Traumatic Brain Injury. Washington DC: American Psychiatric Publishing; 2005: 3–26.
Langlois, JA, Rutland-Brown, W, Wald, MM. The epidemiology and impact of traumatic brain injury: a brief overview. J Head Trauma Rehabil 2006;21:375–8.
Smith, GS, Kraus, JF. Alcohol and residential, recreational, and occupational injuries: a review of the epidemiologic evidence. Annu Rev Public Health 1988;9:99–121.
Salcido, R, Costich, JF. Recurrent traumatic brain injury. Brain Inj 1992;6:293–8.
Kraus, JF, Fife, D, Ramstein, K, et al. The relationship of family income to the incidence, external causes, and outcomes of serious brain injury, San Diego County, California. Am J Public Health 1986;76:1345–7.
Thurman, DJ, Branche, CM, Sniezek, JE. The epidemiology of sports-related traumatic brain injuries in the United States: recent developments. J Head Trauma Rehabil 1998;13:1–8.
Teasdale, G, Jennett, B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974;2:81–4.
Hannay, HJ, Sherer, M. Assessment of outcome from head injury. In Narayan, RK, Wilberger, JE, Povlishock, JT, eds. Neurotrauma. New York: McGraw-Hill; 1996: 723–47.
Williams, DH, Levin, HS, Eisenberg, HM. Mild head injury classification. Neurosurgery 1990;27:422–8.
McMillan, TM, Jongen, EL, Greenwood, RJ. Assessment of post-traumatic amnesia after severe closed head injury: retrospective or prospective? J Neurol Neurosurg Psychiatry 1996;60:422–7.
Russell, WR, Smith, A. Post-traumatic amnesia in closed head injury. Arch Neurol 1961;5:4–17.
Gennarelli, TA, Graham, DI. Neuropathology. In Silver, JM, McAllister, TW, Yudofsky, SC, eds. Textbook of Traumatic Brain Injury. Washington DC: American Psychiatric Publishing; 2005: 27–50.
Levin, HS, Williams, DH, Eisenberg, HM, et al. Serial MRI and neurobehavioural findings after mild to moderate closed head injury. J Neurol Neurosurg Psychiatry 1992;55:255–62.
Levin, HS, Amparo, E, Eisenberg, HM, et al. Magnetic resonance imaging and computerized tomography in relation to the neurobehavioral sequelae of mild and moderate head injuries. J Neurosurg 1987;66:706–13.
Rockswold, GL, Leonard, PR, Nagib, MG. Analysis of management in thirty-three closed head injury patients who “talked and deteriorated”. Neurosurgery 1987;21:51–5.
Levin, HS, Culhane, KA, Mendelsohn, D, et al. Cognition in relation to magnetic resonance imaging in head-injured children and adolescents. Arch Neurol 1993;50:897–905.
Anderson, CV, Bigler, ED, Blatter, DD. Frontal lobe lesions, diffuse damage, and neuropsychological functioning in traumatic brain-injured patients. J Clin Exp Neuropsychol 1995;17:900–8.
Schretlen, DJ, Shapiro, AM. A quantitative review of the effects of traumatic brain injury on cognitive functioning. Int Rev Psychiatry 2003;15:341–9.
Iverson, GL. Outcome from mild traumatic brain injury. Curr Opin Psychiatry 2005;18:301–17.
Lippert-Gruner, M, Wedekind, C, Klug, N. Outcome of prolonged coma following severe traumatic brain injury. Brain Inj 2003;17:49–54.
Giacino, JT, Ashwal, S, Childs, N, et al. The minimally conscious state: definition and diagnostic criteria. Neurology 2002;58:349–53.
Levin, HS. Neurobehavioral sequelae of closed head injury. In Cooper, PR, ed. Head Injury. Baltimore: Williams & Wilkins; 1993: 525–51.
Stuss, DT, Binns, MA, Carruth, FG, et al. The acute period of recovery from traumatic brain injury: posttraumatic amnesia or posttraumatic confusional state? J Neurosurg 1999;90:635–43.
Sherer, M, Nakase-Thompson, R, Yablon, SA, et al. Multidimensional assessment of acute confusion after traumatic brain injury. Arch Phys Med Rehabil 2005;86:896–904.
Dikmen, S, Machamer, J. Neurobehavioral outcomes and their determinants. J Head Trauma Rehabil 1995;10:74–86.
Kalmar, K, Novack, T, Nakase-Richardson, R, et al. Feasibility of a brief neuropsychological test battery during acute inpatient rehabilitation after TBI. Arch Phys Med Rehabil 2008;89:942–9.
Millis, SR, Rosenthal, M, Novack, TA, et al. Long-term neuropsychological outcome after traumatic brain injury. J Head Trauma Rehabil 2001;16:343–55.
Dikmen, S, Reitan, RM, Temkin, NR. Neuropsychological recovery in head injury. Arch Neurol 1983;40:333–8.
Dikmen, S, Machamer, J, Winn, R, et al. Neuropsychological outcome at 1-year post head injury. Neuropsychology 1995;9:80–90.
Ruff, RM, Young, D, Gautille, T, et al. Verbal learning deficits following severe head injury: heterogeneity in recovery over 1 year. J Neurosurg 1991;75:S50–8.
Johnstone, B, Hexum, CL, Ashkanazi, G. Extent of cognitive decline in traumatic brain injury based on estimates of premorbid intelligence. Brain Inj 1995;9:377–84.
Plassman, BL, Havlik, RJ, Steffens, DC, et al. Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias. Neurology 2000;55:1158–66.
Goldman, SM, Tanner, CM, Oakes, D, et al. Head injury and Parkinson's disease risk in twins. Ann Neurol 2006;60:65–72.
Uryu, K, Chen, XH, Martinez, D, et al. Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Exp Neurol 2007;208:185–92.
Mayeux, R, Ottman, R, Maestre, G, et al. Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease. Neurology 1995;45:555–7.
Millar, K, Nicoll, JA, Thornhill, S, et al. Long term neuropsychological outcome after head injury: relation to APOE genotype. J Neurol Neurosurg Psychiatry 2003;74:1047–52.
Riley, GA. Stress and depression in family carers following traumatic brain injury: the influence of beliefs about difficult behaviours. Clin Rehabil 2007;21:82–8.
Winkler, D, Unsworth, C, Sloan, S. Factors that lead to successful community integration following severe traumatic brain injury. J Head Trauma Rehabil 2006;21:8–21.
Starkstein, SE, Robinson, RG. Mechanism of disinhibition after brain lesions. J Nerv Ment Dis 1997;185:108–14.
Cummings, JL, Coffey, CE. Neurobiological basis of behavior. In Coffey, CE, Cummings, JL, eds. Textbook of Geriatric Neuropsychiatry, 2nd edn. Washington DC: American Psychiatric Press; 2000: 81–108.
Kim, E. Agitation, aggression, and disinhibition syndromes after traumatic brain injury. NeuroRehabilitation 2002;17:297–310.
Grafman, J, Schwab, K, Warden, D, et al. Frontal lobe injuries, violence, and aggression: a report of the Vietnam Head Injury Study. Neurology 1996;46:1231–8.
Lequerica, AH, Rapport, LJ, Loeher, K, et al. Agitation in acquired brain injury: impact on acute rehabilitation therapies. J Head Trauma Rehabil 2007;22:177–83.
Leach, LR, Frank, RG, Bouman, , et al. Family functioning, social support and depression after traumatic brain injury. Brain Inj 1994;8:599–606.
Elsinger, P, Grattan, L, L G. Impact of frontal lobe lesions on rehabilitation and recovery from acute brain injury. NeuroRehabilitation 1995;5:161–85.
Baguley, IJ, Cooper, J, Felmingham, K. Aggressive behavior following traumatic brain injury: how common is common? J Head Trauma Rehabil 2006;21:45–56.
Klonoff, PS, Lamb, DG, Henderson, SW, et al. Outcome assessment after milieu-oriented rehabilitation: new considerations. Arch Phys Med Rehabil 1998;79:684–90.
Wood, R, Liossi, C. Neuropsychological and neurobehavioral correlates of aggression following traumatic brain injury. J Neuropsychiatry Clin Neurosci 2006;18:333–41.
Sander, AM, Kreutzer, JS, Fernandez, CC. Neurobehavioral functioning, substance abuse, and employment after brain injury: implications for vocational rehabilitation. J Head Trauma Rehabil 1997;12:28–41.
Reid-Arndt, SA, Nehl, C, Hinkebein, J. The Frontal Systems Behaviour Scale (FrSBe) as a predictor of community integration following a traumatic brain injury. Brain Inj 2007;21:1361–9.
Middleton, FA, Strick, PL. Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res Brain Res Rev 2000;31:236–50.
Cohen, RA, Kaplan, RF, Zuffante, P, et al. Alteration of intention and self-initiated action associated with bilateral anterior cingulotomy. J Neuropsychiatry Clin Neurosci 1999;11:444–53.
Hart, T, Sherer, M, Whyte, J, et al. Awareness of behavioral, cognitive, and physical deficits in acute traumatic brain injury. Arch Phys Med Rehabil 2004;85:1450–6.
Sherer, M, Hart, T, Whyte, J, et al. Neuroanatomic basis of impaired self-awareness after traumatic brain injury: findings from early computed tomography. J Head Trauma Rehabil 2005;20:287–300.
Rogers, JM, Read, CA. Psychiatric comorbidity following traumatic brain injury. Brain Inj 2007;21:1321–33.
Kim, E, Lauterbach, EC, Reeve, A, et al. Neuropsychiatric complications of traumatic brain injury: a critical review of the literature (a report by the ANPA Committee on Research). J Neuropsychiatry Clin Neurosci 2007;19:106–27.
Draper, K, Ponsford, J, Schonberger, M. Psychosocial and emotional outcomes 10 years following traumatic brain injury. J Head Trauma Rehabil 2007;22:278–87.
Anson, K, Ponsford, J. Coping and emotional adjustment following traumatic brain injury. J Head Trauma Rehabil 2006;21:248–59.
Mayou, RA, Black, J, Bryant, B. Unconsciousness, amnesia and psychiatric symptoms following road traffic accident injury. Br J Psychiatry 2000;177:540–5.
Bryant, RAPosttraumatic stress disorder and mild brain injury: controversies, causes and consequences. J Clin Exp Neuropsychol 2001;23:718–28.
Bryant, RA, Marosszeky, JE, Crooks, J, et al. Posttraumatic stress disorder and psychosocial functioning after severe traumatic brain injury. J Nerv Ment Dis 2001;189:109–13.
Burridge, AC, Huw Williams, W, Yates, PJ, et al. Spousal relationship satisfaction following acquired brain injury: the role of insight and socio-emotional skill. Neuropsychol Rehabil 2007;17:95–105.
Ezrachi, O, Ben-Yishay, Y, Kay, T, et al. Predicting employment in traumatic brain injury following neuropsychological rehabilitation. J Head Trauma Rehabil 1991;6:71–84.
Gollaher, K, High, W, Sherer, M, et al. Prediction of employment outcome one to three years following traumatic brain injury (TBI). Brain Inj 1998;12:255–63.
Engberg, AW, Teasdale, TW. Psychosocial outcome following traumatic brain injury in adults: a long-term population-based follow-up. Brain Inj 2004;18:533–45.
Sander, AM, Kreutzer, J, Rosenthal, M, et al. A multicenter longitudinal investigation of return to work and community integration following traumatic brain injury. J Head Trauma Rehabil 1996;11:70–84.
Doctor, JN, Castro, J, Temkin, NR, et al. Workers' risk of unemployment after traumatic brain injury: a normed comparison. J Int Neuropsychol Soc 2005;11:747–52.
Kreutzer, JS, Marwitz, JH, Walker, W, et al. Moderating factors in return to work and job stability after traumatic brain injury. J Head Trauma Rehabil 2003;18:128–38.
Dikmen, SS, Temkin, NR, Machamer, JE, et al. Employment following traumatic head injuries. Arch Neurol 1994;51:177–86.
Vanderploeg, RD, Curtiss, G, Duchnick, JJ, et al. Demographic, medical, and psychiatric factors in work and marital status after mild head injury. J Head Trauma Rehabil 2003;18:148–63.
McCrimmon, S, Oddy, M. Return to work following moderate-to-severe traumatic brain injury. Brain Inj 2006;20:1037–46.
Corrigan, JD, Rust, E, Lamb-Hart, GL. The nature and extent of substance abuse problems in persons with traumatic brain injury. J Head Trauma Rehabil 1995;10:29–46.
Corrigan, JD. Substance abuse as a mediating factor in outcome from traumatic brain injury. Arch Phys Med Rehabil 1995;76:302–9.
Hopewell, CA. Driving assessment issues for practicing clinicians. J Head Trauma Rehabil 2002;17:48–61.
Novack, TA, Banos, JH, Alderson, AL, et al. UFOV performance and driving ability following traumatic brain injury. Brain Inj 2006;20:455–61.
Sherer, M, Novack, T. Neuropsychological assessment after traumatic brain injury in adults. In Prigatano, GP, Pliskin, NH, eds. Clinical Neuropsychology and Cost Outcome Research. New York: Psychology Press; 2003: 39–60.
Kashluba, S, Hanks, RA, Casey, JE, et al. Neuropsychologic and functional outcome after complicated mild traumatic brain injury. Arch Phys Med Rehabil 2008;89:904–11.
Iverson, GL. Complicated vs uncomplicated mild traumatic brain injury: acute neuropsychological outcome. Brain Inj 2006;20:1335–44.
McCrea, M, Guskiewicz, KM, Marshall, SW, et al. Acute effects and recovery time following concussion in collegiate football players: the NCAA Concussion Study. J Am Med Assoc 2003;290:2556–63.
Iverson, GL, Brooks, BL, Collins, MW, et al. Tracking neuropsychological recovery following concussion in sport. Brain Inj 2006;20:245–52.
Bleiberg, J, Cernich, AN, Cameron, K, et al. Duration of cognitive impairment after sports concussion. 2004;54:1073–8.
Randolph, C, McCrea, M, Barr, WB. Is neuropsychological testing useful in the management of sport-related concussion? J Athl Train 2005;40:139–52.
McCrea, M, Barr, WB, Guskiewicz, K, et al. Standard regression-based methods for measuring recovery after sport-related concussion. J Int Neuropsychol Soc 2005;11:58–69.
Giacino, JT, Kalmar, K, Whyte, J. The JFK Coma Recovery Scale-Revised: measurement characteristics and diagnostic utility. Arch Phys Med Rehabil 2004;85:2020–9.
Levin, HS, O'Donnell, VM, Grossman, RG. The Galveston Orientation and Amnesia Test: a practical scale to assess cognition after head injury. J Nerv Ment Dis 1979;167:675–84.
Jackson, WT, Novack, TA, Dowler, RN. Effective serial measurement of cognitive orientation in rehabilitation: the Orientation Log. Arch Phys Med Rehabil 1998;79:718–20.
Pastorek, NJ, Hannay, HJ, Contant, CS. Prediction of global outcome with acute neuropsychological testing following closed-head injury. J Int Neuropsychol Soc 2004;10:807–17.
Sherer, M, Sander, AM, Nick, TG, et al. Early cognitive status and productivity outcome after traumatic brain injury: findings from the TBI model systems. Arch Phys Med Rehabil 2002;83:183–92.
Atchison, TB, Sander, AM, Struchen, MA, et al. Relationship between neuropsychological test performance and productivity at 1-year following traumatic brain injury. Clin Neuropsychol 2004;18:249–65.
Ponsford, J, Draper, K, Schonberger, M. Functional outcome 10 years after traumatic brain injury: its relationship with demographic, injury severity, and cognitive and emotional status. J Int Neuropsychol Soc 2008;14:233–42.
Hanks, RA, Millis, SR, Ricker, JH, et al. The predictive validity of a brief inpatient neuropsychologic battery for persons with traumatic brain injury. Arch Phys Med Rehabil 2008;89:950–7.
Mittenberg, W, Canyock, EM, Condit, D, et al. Treatment of post-concussion syndrome following mild head injury. J Clin Exp Neuropsychol 2001;23:829–36.
Paniak, C, Toller-Lobe, G, Reynolds, S, et al. A randomized trial of two treatments for mild traumatic brain injury: 1 year follow-up. Brain Inj 2000;14:219–26.
Cope, DN. The effectiveness of traumatic brain injury rehabilitation: A review. Brain Inj 1995;9:649–70.
Malec, JF, Basford, JS. Postacute brain injury rehabilitation. Arch Phys Med Rehabil 1996;77:198–207.
Sander, AM, Roebuck, TM, Struchen, MA, et al. Long-term maintenance of gains obtained in postacute rehabilitation by persons with traumatic brain injury. J Head Trauma Rehabil 2001;16:1–19.
High, WM., Roebuck-Spencer, T, Sander, AM, et al. Early versus later admission to postacute rehabilitation: impact on functional outcome after traumatic brain injury. Arch Phys Med Rehabil 2006;87:334–42.
Cicerone, KD, Dahlberg, C, Malec, JF, et al. Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch Phys Med Rehabil 2005;86:1681–92.
Milders, M, Deelman, B, Berg, I. Rehabilitation of memory for people's names. Memory 1998;6:21–36.
Goverover, Y, Johnston, MV, Toglia, J, et al. Treatment to improve self-awareness in persons with acquired brain injury. Brain Inj 2007;21:913–23.
Cheng, SK, Man, DW. Management of impaired self-awareness in persons with traumatic brain injury. Brain Inj 2006;20:621–8.
Dahlberg, CA, Cusick, CP, Hawley, , et al. Treatment efficacy of social communication skills training after traumatic brain injury: a randomized treatment and deferred treatment controlled trial. Arch Phys Med Rehabil 2007;88:1561–73.
Anson, K, Ponsford, J. Evaluation of a coping skills group following traumatic brain injury. Brain Inj 2006;20:167–78.
Wehman, PH, Revell, WG, Kregel, J, et al. Supported employment: an alternative model for vocational rehabilitation of persons with severe neurologic, psychiatric, or physical disability. Arch Phys Med Rehabil 1991;72:101–5.
Warden, DL, Gordon, B, McAllister, TW, et al. Guidelines for the pharmacologic treatment of neurobehavioral sequelae of traumatic brain injury. J Neurotrauma 2006;23:1468–501.
,Think First National Brain Injury Prevention Foundation (Online). Fast Facts: Traumatic Brain Injury. 2008. http://www.thinkfirst.org/Documents/FastFacts/TFbrain368.pdf. (Accessed July 1, 2008.)
Attewell, RG, Glase, K, McFadden, M. Bicycle helmet efficacy: a meta-analysis. Accid Anal Prev 2001;33:345–52.
Pintar, FA, Yoganandan, N, Gennarelli, TA. Airbag effectiveness on brain trauma in frontal crashes. Annu Proc Assoc Adv Automot Med 2000;44:149–69.
Hillary, FG, Schatz, P, Moelter, ST, et al. Motor vehicle collision factors influence severity and type of TBI. Brain Inj 2002;16:729–41.
Collins, M, Lovell, MR, Iverson, GL, et al. Examining concussion rates and return to play in high school football players wearing newer helmet technology: a three-year prospective cohort study. Neurosurgery 2006;58:275–86.
Corrigan, JD, Whiteneck, G, Mellick, D. Perceived needs following traumatic brain injury. J Head Trauma Rehabil 2004;19:205–16.
Bell, KR, Temkin, NR, Esselman, PC, et al. The effect of a scheduled telephone intervention on outcome after moderate to severe traumatic brain injury: a randomized trial. Arch Phys Med Rehabil 2005;86:851–6.
Ricker, JH, Rosenthal, M, Garay, E, et al. Telerehabilitation needs: a survey of persons with acquired brain injury. J Head Trauma Rehabil 2002;17:242–50.
Levinson, DM, Reeves, DL. Monitoring recovery from traumatic brain injury using automated neuropsychological assessment metrics (ANAM V1.0). Arch Clin Neuropsychol 1997;12:155–66.
Perlstein, WM, Cole, MA, Demery, JA, et al. Parametric manipulation of working memory load in traumatic brain injury: behavioral and neural correlates. J Int Neuropsychol Soc 2004;10:724–41.
McAllister, TW, Sparling, MB, Flashman, , et al. Differential working memory load effects after mild traumatic brain injury. Neuroimage 2001;14:1004–12.
Rutgers, DR, Toulgoat, F, Cazejust, J, et al. White matter abnormalities in mild traumatic brain injury: a diffusion tensor imaging study. AJNR Am J Neuroradiol 2008;29:514–9.
Benson, RR, Meda, SA, Vasudevan, S, et al. Global white matter analysis of diffusion tensor images is predictive of injury severity in traumatic brain injury. J Neurotrauma 2007;24:446–59.
Rizzo, AA, Buckwalter, JG, Neumann, U. Virtual reality and cognitive rehabilitation: a brief review of the future. J Head Trauma Rehabil 1997;12:1–15.
Lengenfelder, J, Schultheis, MT, Al-Shihabi, T, et al. Divided attention and driving: a pilot study using virtual reality technology. J Head Trauma Rehabil 2002;17:26–37.