Skip to main content Accessibility help
×
Hostname: page-component-84b7d79bbc-x5cpj Total loading time: 0 Render date: 2024-07-31T23:07:35.596Z Has data issue: false hasContentIssue false

Chapter 22 - Optimizing functional status in older adults with cancer

from Part 4 - Symptom management and supportive care of older adults

Published online by Cambridge University Press:  05 August 2011

Arti Hurria
Affiliation:
City of Hope Cancer Center, California
Harvey Jay Cohen
Affiliation:
Duke University Medical Center, Durham
Get access

Summary

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Balducci, L, Beghe, C. The application of the principles of geriatrics to the management of the older person with cancer. Crit Rev Oncol Hematol. 2000;35(3):147–154.CrossRefGoogle ScholarPubMed
Hurria, A. Incorporation of geriatric principles in oncology clinical trials. J Clin Oncol. 2007;25(34):5350–5351.CrossRefGoogle ScholarPubMed
Schubert, CC, Gross, C, Hurria, A. Functional assessment of the older patient with cancer. Oncology. 2008;22(8):916–922; discussion 925, 928.Google ScholarPubMed
Karnofsky, D, Burchenal, JH. Evaluation of Chemotherapeutic Agents. New York: Columbia University Press; 1949.Google Scholar
Mor, V, Laliberte, L, Morris, JN. The Karnofsky Performance Status Scale: an examination of its reliability and validity in a research setting. Cancer. 1984;53(9):2002–2007.3.0.CO;2-W>CrossRefGoogle Scholar
Oken, MM, Creech, RH, Tormey, DC. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982;5(6):649–655.CrossRefGoogle ScholarPubMed
Hays, RD, Sherbourne, CD, Mazel, RM. The RAND 36-item health survey 1.0. Health Econ. 1993;2(3):217–227.CrossRefGoogle ScholarPubMed
Overcash, J, Extermann, M, Parr, J. Validity and reliability of the FACT-G scale for use in the older person with cancer. Am J Clin Oncol. 2001;24(6):591–596.CrossRefGoogle ScholarPubMed
Jemal, A, Center, MM, Ward, E. Cancer occurrence. Methods Mol Biol. 2009;471:3–29.CrossRefGoogle ScholarPubMed
Yancik, R, Ries, . Cancer in older persons: an international issue in an aging world. Semin Oncol. 2004;31(2):128–136.CrossRefGoogle Scholar
Hurria, A. Clinical trials in older adults with cancer: past and future. Oncology. 2007;21(3):351–358; discussion 363–364, 367.Google ScholarPubMed
Given, B, Given, C, Azzouz, F. Physical functioning of elderly cancer patients prior to diagnosis and following initial treatment. Nurs Res. 2001;50(4):222–232.CrossRefGoogle ScholarPubMed
Cheville, AL, Troxel, AB, Basford, JR. Prevalence and treatment patterns of physical impairments in patients with metastatic breast cancer. J Clin Oncol. 2008;26(16):2621–2629.CrossRefGoogle ScholarPubMed
Bylow, K, Dale, W, Mustian, K. Falls and physical performance deficits in older patients with prostate cancer undergoing androgen deprivation therapy. Urology. 2008;72(2):422–427.CrossRefGoogle ScholarPubMed
McQuellon, RP, Thaler, HT, Cella, D. Quality of life (QOL) outcomes from a randomized trial of cisplatin versus cisplatin plus paclitaxel in advanced cervical cancer: a Gynecologic Oncology Group study. Gynecol Oncol. 2006;101(2):296–304.CrossRefGoogle ScholarPubMed
Extermann, M, Hurria, A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol. 2007;25(14):1824–1831.CrossRefGoogle ScholarPubMed
Hewitt, M, Rowland, JH, Yancik, R. Cancer survivors in the United States: age, health, and disability. J Gerontol. 2003;58(1):M82–M91.CrossRefGoogle ScholarPubMed
Malhotra, Vikas MCP. Functional problems in the patient with cancer. In: Rose BD, ed. UpToDate. Wellesley UpToDate, MA, 2008.
Sweeney, C, Schmitz, KH, Lazovich, D. Functional limitations in elderly female cancer survivors. J Natl Cancer Inst. 2006;98(8):521–529.CrossRefGoogle ScholarPubMed
Ness, KK, Hudson, MM, Ginsberg, JP. Physical performance limitations in the Childhood Cancer Survivor Study cohort. J Clin Oncol. 2009;27(14):2382–2389.CrossRefGoogle ScholarPubMed
Hurria, A, Lichtman, SM, Gardes, J. Identifying vulnerable older adults with cancer: integrating geriatric assessment into oncology practice. J Am Geriatr Soc. 2007;55(10):1604–1608.CrossRefGoogle ScholarPubMed
Gosney, MA. Clinical assessment of elderly people with cancer. Lancet Oncol. 2005;6(10):790–797.CrossRefGoogle ScholarPubMed
Rodin, MB, Mohile, SG. A practical approach to geriatric assessment in oncology. J Clin Oncol. 2007;25(14):1936–1944.CrossRefGoogle Scholar
Wildiers, H. Mastering chemotherapy dose reduction in elderly cancer patients. Eur J Cancer. 2007;43(15):2235–2241.CrossRefGoogle ScholarPubMed
Kurtz, ME, Kurtz, JC, Stommel, M. Loss of physical functioning among geriatric cancer patients: relationships to cancer site, treatment, comorbidity and age. Eur J Cancer. 1997;33(14):2352–2358.CrossRefGoogle Scholar
Wedding, U, Kodding, D, Pientka, L. Physicians'; judgement and comprehensive geriatric assessment (CGA) select different patients as fit for chemotherapy. Crit Rev Oncol Hematol. 2007;64(1):1–9.CrossRefGoogle ScholarPubMed
Balducci, L. Aging, frailty, and chemotherapy. Cancer Control. 2007;14(1):7–12.CrossRefGoogle ScholarPubMed
Extermann, M, Meyer, J, McGinnis, M. A comprehensive geriatric intervention detects multiple problems in older breast cancer patients. Crit Rev Oncol Hematol. 2004;49(1):69–75.CrossRefGoogle ScholarPubMed
Repetto, L, Fratino, L, Audisio, RA. Comprehensive geriatric assessment adds information to Eastern Cooperative Oncology Group performance status in elderly cancer patients: an Italian Group for Geriatric Oncology study. J Clin Oncol. 2002;20(2):494–502.CrossRefGoogle Scholar
Balducci, L, Extermann, M. Management of cancer in the older person: a practical approach. Oncologist. 2000;5(3):224–237.CrossRefGoogle ScholarPubMed
Chen, H, Cantor, A, Meyer, J. Can older cancer patients tolerate chemotherapy? A prospective pilot study. Cancer. 2003;97(4):1107–1114.CrossRefGoogle ScholarPubMed
Galvao, DA, Taaffe, DR, Spry, N. Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer. Prostate Cancer Prostatic Dis. 2007;10(4):340–346.CrossRefGoogle ScholarPubMed
Weert, E, Hoekstra-Weebers, J, Grol, B. A multidimensional cancer rehabilitation program for cancer survivors: effectiveness on health-related quality of life. J Psychosom Res. 2005;58(6):485–496.CrossRefGoogle ScholarPubMed
McCorkle, R, Strumpf, NE, Nuamah, IF. A specialized home care intervention improves survival among older post-surgical cancer patients. J Am Geriatr Soc. 2000;48(12):1707–1713.Google ScholarPubMed
Rao, AV, Hsieh, F, Feussner, JR. Geriatric evaluation and management units in the care of the frail elderly cancer patient. J Gerontol. 2005;60(6):798–803.CrossRefGoogle ScholarPubMed
Jahnigen, DW, Applegate, WB, Cohen, HJ. Working group recommendations: research on content and efficacy of geriatric evaluation and management interventions. J Am Geriatr Soc. 1991;39(9 Pt 2):42S–44S.CrossRefGoogle Scholar
Cheema, B, Gaul, CA, Lane, K. Progressive resistance training in breast cancer: a systematic review of clinical trials. Breast Cancer Res Treat. 2008;109(1):9–26.CrossRefGoogle ScholarPubMed
Liu, RD, Chinapaw, MJ, Huijgens, PC. Physical exercise interventions in haematological cancer patients, feasible to conduct but effectiveness to be established: a systematic literature review. Cancer Treat Rev. 2009;35(2):185–192.CrossRefGoogle ScholarPubMed
Schmitz, KH, Holtzman, J, Courneya, KS. Controlled physical activity trials in cancer survivors: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2005;14(7):1588–1595.CrossRefGoogle ScholarPubMed
McNeely, ML, Campbell, KL, Rowe, BH. Effects of exercise on breast cancer patients and survivors: a systematic review and meta-analysis. Can Med Assoc J. 2006;175(1):34–41.CrossRefGoogle ScholarPubMed
Morey, MC, Snyder, DC, Sloane, R. Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial. J Am Med Assoc. 2009;301(18):1883–1891.CrossRefGoogle ScholarPubMed
Segal, RJ, Reid, RD, Courneya, KS. Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2003;21(9):1653–1659.CrossRefGoogle ScholarPubMed
Segal, RJ, Reid, RD, Courneya, KS. Randomized controlled trial of resistance or aerobic exercise in men receiving radiation therapy for prostate cancer. J Clin Oncol. 2009;27(3):344–351.CrossRefGoogle ScholarPubMed
Courneya, KS, Segal, RJ, Mackey, JR. Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. J Clin Oncol. 2007;25(28):4396–4404.CrossRefGoogle ScholarPubMed
Courneya, KS, Segal, RJ, Gelmon, K. Six-month follow-up of patient-rated outcomes in a randomized controlled trial of exercise training during breast cancer chemotherapy. Cancer Epidemiol Biomarkers Prev. 2007;16(12):2572–2578.CrossRefGoogle Scholar
May, AM, Duivenvoorden, HJ, Korstjens, I. The effect of group cohesion on rehabilitation outcome in cancer survivors. Psychooncology. 2008;17(9):917–925.CrossRefGoogle ScholarPubMed
Lowe, SS, Watanabe, SM, Courneya, KS. Physical activity as a supportive care intervention in palliative cancer patients: a systematic review. J Support Oncol. 2009;7(1):27–34.Google ScholarPubMed
Vargo, MM. The oncology-rehabilitation interface: better systems needed. J Clin Oncol. 2008;26(16):2610–2611.CrossRefGoogle ScholarPubMed
Korstjens, I, Mesters, I, Gijsen, B. Cancer patients'; view on rehabilitation and quality of life: a programme audit. Eur J Cancer Care (Engl). 2008;17(3):290–297.CrossRefGoogle ScholarPubMed
Weert, E, Hoekstra-Weebers, JE, Grol, BM. Physical functioning and quality of life after cancer rehabilitation. Int J Rehabil Res. 2004;27(1):27–35.CrossRefGoogle ScholarPubMed
Mikkelsen, TH, Sondergaard, J, Jensen, AB. Cancer rehabilitation: psychosocial rehabilitation needs after discharge from hospital? Scand J Prim Health Care. 2008;26(4):216–221.CrossRefGoogle ScholarPubMed
Morris, GS, Gallagher, GH, Baxter, MF. Pulmonary rehabilitation improves functional status in oncology patients. Arch Phys Med Rehabil. 2009;90(5):837–841.CrossRefGoogle ScholarPubMed
Courneya, KS, Vallance, JKH, McNeely, ML. Exercise issues in older cancer survivors. Crit Rev Oncol Hematol. 2004;51(3):249–261.CrossRefGoogle ScholarPubMed
Rao, AV, Demark-Wahnefried, W. The older cancer survivor. Crit Rev Oncol Hematol. 2006;60(2):131–143.CrossRefGoogle ScholarPubMed
Ayanian, JZ, Jacobsen, PB. Enhancing research on cancer survivors. J Clin Oncol. 2006;24(32):5149–5153.CrossRefGoogle ScholarPubMed
Grunfeld, E. Looking beyond survival: how are we looking at survivorship? J Clin Oncol. 2006;24(32):5166–5169.CrossRefGoogle ScholarPubMed
Cicco, M, Bortolussi, R, Fantin, D. Supportive therapy of elderly cancer patients. Crit Rev Oncol Hematol. 2002;42(2):189–211.CrossRefGoogle ScholarPubMed
Portenoy, RK. Pain management in the older cancer patient. Oncology. 1992;6(2 suppl):86–98.Google ScholarPubMed
Delgado-Guay, MO, Bruera, E. Management of pain in the older person with cancer. Oncology. 2008;22(1):56–61.Google ScholarPubMed
Delgado-Guay, MO, Bruera, E. Management of pain in the older person with cancer. Part 2: treatment options. Oncology. 2008;22(2):148–152; discussion 152, 155, 160 passim.Google ScholarPubMed
Christo, PJ, Mazloomdoost, D. Interventional pain treatments for cancer pain. Ann N Y Acad Sci. 2008;1138:299–328.CrossRefGoogle ScholarPubMed
Christo, PJ, Mazloomdoost, D. Cancer pain and analgesia. Ann N Y Acad Sci. 2008;1138:278–298.CrossRefGoogle ScholarPubMed
Maarten, M. Cancer-associated malnutrition: an introduction. Eur J Oncol Nurs. 2005;9:S35–S38.Google Scholar
Skipworth, RJ, Fearon, KC. The scientific rationale for optimizing nutritional support in cancer. Eur J Gastroenterol Hepatol. 2007;19(5):371–377.CrossRefGoogle Scholar
Skipworth, RJ, Stewart, GD, Dejong, CH. Pathophysiology of cancer cachexia: much more than host-tumour interaction? Clin Nutr. 2007;26(6):667–676.CrossRefGoogle ScholarPubMed
Argiles, JM, Busquets, S, Moore-Carrasco, R. Targets in clinical oncology: the metabolic environment of the patient. Front Biosci. 2007;12:3024–3051.CrossRefGoogle ScholarPubMed
Argiles, JM. Cancer-associated malnutrition. Eur J Oncol Nurs. 2005;9(suppl 2):39–S50.CrossRefGoogle ScholarPubMed
Toles, M, Demark-Wahnefried, W. Nutrition and the cancer survivor: evidence to guide oncology nursing practice. Semin Oncol Nurs. 2008;24(3):171–179.CrossRefGoogle ScholarPubMed
Irwin, ML, Mayne, ST. Impact of nutrition and exercise on cancer survival. Cancer J. 2008;14(6):435–441.CrossRefGoogle ScholarPubMed
Demark-Wahnefried, W, Clipp, EC, Morey, MC. Physical function and associations with diet and exercise: results of a cross-sectional survey among elders with breast or prostate cancer. Int J Behav Nutr Phys Act. 2004;1(1):16.CrossRefGoogle ScholarPubMed
Ottery, FD. Supportive nutrition to prevent cachexia and improve quality of life. Semin Oncol. 1995;22(2 suppl 3):98–111.Google ScholarPubMed
Michelle, D. Nutritional screening and assessment in cancer-associated malnutrition. Eur J Oncol Nurs. 2005;9:S64–S73.Google Scholar
Bokhorst-de van Der Schueren, MA. Nutritional support strategies for malnourished cancer patients. Eur J Oncol Nurs. 2005;9 (suppl):74–83.CrossRefGoogle ScholarPubMed
Bosaeus, I. Nutritional support in multimodal therapy for cancer cachexia. Support Care Cancer. 2008;16(5):447–451.CrossRefGoogle ScholarPubMed
Mattox, TW. Treatment of unintentional weight loss in patients with cancer. Nutr Clin Pract. 2005;20(4):400–410.CrossRefGoogle ScholarPubMed
Seruga, B, Zhang, H, Bernstein, LJ. Cytokines and their relationship to the symptoms and outcome of cancer. Nat Rev Cancer. 2008;8(11):887–899.CrossRefGoogle Scholar
Stommel, M, Given, BA, Given, CW. Depression and functional status as predictors of death among cancer patients. Cancer. 2002;94(10):2719–2727.CrossRefGoogle ScholarPubMed
Raji, MA, Kuo, YF, Freeman, JL. Effect of a dementia diagnosis on survival of older patients after a diagnosis of breast, colon, or prostate cancer: implications for cancer care. Arch Intern Med. 2008;168(18):2033–2040.CrossRefGoogle ScholarPubMed
Kurtz, ME, Kurtz, JC, Stommel, M. The influence of symptoms, age, comorbidity and cancer site on physical functioning and mental health of geriatric women patients. Women Health. 1999;29(3):1–12.CrossRefGoogle ScholarPubMed
Poppelreuter, M, Weis, J, Bartsch, HH. Effects of specific neuropsychological training programs for breast cancer patients after adjuvant chemotherapy. J Psychosoc Oncol. 2009;27(2):274–296.CrossRefGoogle ScholarPubMed
Poppelreuter, M, Weis, J, Mumm, A. Rehabilitation of therapy-related cognitive deficits in patients after hematopoietic stem cell transplantation. Bone Marrow Transplant. 2008;41(1):79–90.CrossRefGoogle ScholarPubMed
Courneya, KS, Mackey, JR, Bell, GJ. Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol. 2003;21(9):1660–1668.CrossRefGoogle ScholarPubMed
May, AM, Korstjens, I, Weert, E. Long-term effects on cancer survivors'; quality of life of physical training versus physical training combined with cognitive-behavioral therapy: results from a randomized trial. Support Care Cancer. 2009;17(6):653–663.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×