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Case 16 - A 28-Year-Old Woman with Secondary Amenorrhea and Family History of Mental Retardation (Fragile X Premutation)

from Section III - Amenorrhea and Abnormal Vaginal Bleeding

Published online by Cambridge University Press:  20 February 2019

David Chelmow
Affiliation:
Virginia Commonwealth University
Nicole W. Karjane
Affiliation:
Virginia Commonwealth University
Hope A. Ricciotti
Affiliation:
Harvard Medical School
Amy E. Young
Affiliation:
University of Texas, Austin
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Office Gynecology
A Case-Based Approach
, pp. 47 - 50
Publisher: Cambridge University Press
Print publication year: 2019

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References

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Panay, N, Kalu. Management of premature ovarian failure. Best Pract Res Clin Obstet Gynaecol 2009;23:129140.CrossRefGoogle ScholarPubMed
Conway, GS, Hettiarachchi, S, Murray, A et al. Fragile X premutation in familial premature ovarian failure. Lancet 1995;346:309310.CrossRefGoogle ScholarPubMed
Conway, GS. Premature ovarian failure and FMR1 gene mutations: an update. Ann Endocrin 2010;71:215217.Google Scholar
Cornish, K, Turk, J, Hagerman, R. The fragile X continuum: new advances and perspectives. J Intellect Disabil Res 2008;52:469482.Google Scholar
Ryan, JR, Arici, A. Fragile X and reproduction. Curr Opin Obstet Gynecol 2008 June;20(3):216220.Google Scholar
Hoyos, LR, Thakur, M. Fragile X premutation in women: recognizing the health challenges beyond primary ovarian insufficiency. J Assist Reprod Genet 2017;34:315323.CrossRefGoogle ScholarPubMed
American College of Obstetricians and Gynecologists. Primary ovarian insufficiency in adolescents and young women. Committee Opinion No. 605.Obstet Gynecol 2014;123:193197.Google Scholar
Rossouw, JE, Anderson, GL, Prentice, RL et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA 2002;288:321333.Google ScholarPubMed

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