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Chapter 42 - Medical Method for Termination of Pregnancy

from Section 5 - Termination of Pregnancy

Published online by Cambridge University Press:  25 March 2022

By
Teresa Bombas
Edited by
Johannes Bitzer  and
Tahir A. Mahmood
Johannes Bitzer
Affiliation:
University Women’s Hospital, Basel
Tahir A. Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
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Summary

Indications, medical methods, mifepriston, misorprostol

Keywords

Mifepristonmisoprostolapplication
Type
Chapter
Information
Handbook of Contraception and Sexual Reproductive Healthcare , pp. 277 - 288
Publisher: Cambridge University Press
Print publication year: 2022

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References

Further Reading

World Health Organization. Resolution WHA20. 41. Health aspects of population dynamics. In, Twentieth World Health Assembly, Geneva, 25 May 1967. Resolutions and decisions. Geneva: WHO; 1967.Google Scholar
United Nations. Report of the International Conference on Population and Development New York: United Nations; 1994.Google Scholar
Center for Reproductive Rights. By the Numbers: The Legal Status of Abortion Worldwide. Available from: https://reproductiverights.org/sites/default/files/documents/World-Abortion-Map-ByTheNumbers.pdf.Google Scholar
World Health Organization. Preventing Unsafe Abortion. Available from: www.who.int/news-room/fact-sheets/detail/preventing-unsafe-abortion (last updated February 18, 2018).Google Scholar
World Health Organization. Safe Abortion: Technical and Policy Guidance for Health Systems. Geneva: World Health Organization; 2012.Google Scholar
Raymond, EG, Grimes, DA. The comparative safety of legal induced abortion and childbirth in the United States. Obstet Gynecol 2012;119(2 Pt 1):215e9.CrossRefGoogle ScholarPubMed
World Health Organization. Clinical Practice Handbook for Safe Abortion. Geneva: WHO; 2014.Google Scholar
World Health Organization. Medical Management of Abortion. Geneva: World Health Organization; 2018.Google Scholar
World Health Organization. WHO Model List of Essential Medicines (20th List). March 2017 (Amended August 2017). Geneva: World Health Organization; 2017.Google Scholar
Tang, OS, et al. Misoprostol: pharmacokinetic profiles, effects on uterus and side-effects. Int J Gynaecol Obstet 2007;99 Suppl 2:S160–7.CrossRefGoogle ScholarPubMed
Ziemen, M, et al. Absortion kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997; 90(1):88–92.CrossRefGoogle Scholar
Fiala, C, et al. Early Medical Abortion. A Practical Guide for Health Care Professionals. 2nd Ed. 2018.Google Scholar
Gemzell-Danielsson, K, at al. Medical abortion beyond 1st trimester including fetal dead in utero. A practical guide for health care professionals. 2015.Google Scholar
Berar, V et al. Instability of misoprostol tablets stored outside the blister: a potential serious concern for clinical outcome in medical abortion. PLoS ONE 9(12):e112401.CrossRefGoogle Scholar
Saav, I, et al. Medical abortion in lactating women: low levels of mifepristone in breast milk. Acta Obstet Gynecol Scand 2010; 89(5):618–22.Google Scholar
Nathalie, K, et al. Modern methods to induce abortion: Safety, efficacy and choice. Best Practice & Research Clinical Obstetrics and Gynaecology 2020; 63: 37e44.Google Scholar
Fiala, C, et al. Pain during medical abortion, the impact of the regimen: a neglected issue – a review. Eur J Contracept Reprod Health Care 2014;19:404–19.CrossRefGoogle ScholarPubMed
Haute Autority de Santé. Interruption volontaire de grossesse par méthode médicamenteuse. Argu-mentaire. HAS; 2018. www.has-sante.fr/jcms/p_3223429/fr/interruption-volontaire-de-grossesse-par-methode-medicamenteuse-mise-a-jour.Google Scholar
International Federation of Gynecology and Obstetrics. FIGO Working Group on Prevention of Unsafe Abortion and its Consequences. The combination of mifepristone and misoprostol for the termination of pregnancy. Int J Gynaecol Obstet 2011;115:1–4.Google Scholar
Royal College of Obstetricians and Gynaecologists. Best Practice in Comprehensive Abortion Care. UK: RCOG; 2018.Google Scholar
Fiala, C, et al. Pain management for up to 9 weeks medical abortion: An international survey among abortion providers. European Journal of Obstetrics & Gynecology and Reproductive Biology 2018; 225:181–4.Google Scholar
Raymond, EG, et al. Serial multilevel urine pregnancy testing to assess medical abortion outcome: a metaanalysis. Contraception 2017;95:442–8.Google Scholar
Oppegaard, KS, et al. Clinical follow-up compared with self-assessment of outcome after medical abortion: a multicenter, non-inferiority, randomized, controlled trial. Lancet 2015;385:698–704.Google Scholar
Fiala, C, et al. Outcome of first trimester medical termination of pregnancy: definitions and management. The European Society of Contraception and Reproductive Health 2018;23(6):451-7.Google Scholar

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