Genetics and development of neural tube defects. J Pathol
Possible prevention of neural tube defects by periconceptional vitamin supplementation. Lancet
Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet
Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med
Prevention of neural tube defects with folic acid in China. China-US collaborative project for neural tube defect prevention. N Engl J Med
1999;341(20):1485–90., , .
Effects and safety of periconceptional folate supplementation for preventing birth defects. Cochrane Database Syst Rev
2010; (10)CD007950., , , .
Use of folic acid supplements, particularly by low-income and young women: a series of systematic reviews to inform public health policy in the UK. Public Health Nutr
2009.. Food Standards Australia New Zealand,
Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA
2001;285:2981–6., , , , .
2007.. Pre-conceptional Vitamin/Folic Acid Supplementation 2007: The Use of Folic Acid in Combination with a Multivitamin Supplement for the Prevention of Neural Tube Defects and Other Congenital Anomalies. No. 201 (Replaces guideline No. 138), December
2003.. Periconceptional folic acid and food fortification in the prevention of neural tube defects. Scientific Advisory Committee Opinion Paper 4 April
A genetic defect in 5, 10 methylenetetrahydrofolate reductase in neural tube defects. QJM
1995;88:763–6., , , et al.
Myelomeningocele: a review of the epidemiology, genetics, risk factors for conception, prenatal diagnosis and prognosis for affected individuals. Obstet Gynecol Surv
2007;62(7):471–79., , .
Aneuploidy among prenatally detected neural tube defects. Am J Med Genet
1996;61(2):171–3. Jr, , , et al.
Prenatally diagnosed neural tube defects; ultrasound, chromosome, and autopsy or postnatal findings in 212 cases. Am J Med Genet
1998;77:317–21., , , et al.
Prenatally detected fetal myelomeningocele: is karyotype analysis warranted?
1995;194(2):491–4., , .
Chromosomal abnormalities in fetuses with open neural tube defects: prenatal identification with ultrasound. Ultrasound Obstet Gynecol
2004;23(4):352–6., , , et al.
Human Malformations and Related Anomalies, Vol. 11. New York, Oxford University Press, 1993; 116. Brain and spinal cord. In: , , , eds.
Neural tube defects in Eastern Ontario and Western Quebec; demography and family data. Am J Med Genet
Syndromes, disorders and maternal risk factors associated with neural tube defects (I-VII). Taiwan J Obstet Gynecol
2008;47(1):1–17. 47(2):131–49. 47(3):267–82..
Maternal obesity and risk of neural tube defects: a metaanalysis. Am J Obstet Gynecol
2008;198(6):611–19., , , .
Maternal overweight and obesity and the risk of congenital anomalies; a systematic review and meta-analysis. JAMA
2009;301(6):636–50., , , .
Neural tube defect genes and maternal diabetes during pregnancy. Birth Defects Res A
Risk of congenital anomalies detected during antenatal serum screening in women with pregestational diabetes. QJM
Risk of neural tube defect-affected pregnancies among obese women. JAMA
1996;275:1093–6., , .
Body mass index and serum folate in childbearing women. Eur J Epidemiol
Prepregnancy obesity: a complex risk factor for selected birth defects. Birth Defects Res A
2010;88:804–10., , .
2011.. Reprotox, Micromedex database,
2011.. Reprotox, Micromedex database
Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register. Neurology
2011.. Reprotox, Micromedex database,
Maternal exposures to cigarette smoke, alcohol, and street drugs and neural tube defect occurrence in offspring. Matern Child Health J
2008;12:394–401., , .
Discoverer of maternal hyperthermia as a human teratogen. Birth Defects Res A
Genetic Disorders and the Fetus: Diagnosis, Prevention and Treatment, 3rd edn. Baltimore, Johns Hopkins University Press. 1992; 1..
Hyperthermia-induced neural tube defects: the protective effect of folic acid. International Thermal Physiology Symposium, August
2001. 32(2) Supplement 1., , .
Maternal hyperthermia and the risk for neural tube defects in offspring: systematic review and meta-analysis. Epidemiology
2005;16:216–19., , , .
A population-based case–control study of risk factors for neural tube defects in four high-prevalence areas of Shanxi province, China. Paediatr Perinat Ep
2006;20(1):43–53., , , .
Maternal heat exposure and neural tube defects. JAMA
1992;268:882–5., , , et al.
Amniotic band sequence associated with fronto-ethmoidal meningoencephalocele: case report. Clin Genet
2010;78(Suppl 1):17., , .
Intestinal mucosa on top of a rudimentary occipital meningocele in amniotic rupture sequence: disorganization-like syndrome, homeotic transformation, abnormal surface encounter or endoectodermal adhesion?
2002;11:9–13., , .
Open thoracic meningocele associated with amniotic band syndrome. Pediatr Neurosurg
Amniotic band syndrome associated with sacral meningocele and anal atresia. Pediatr Int
2010;52(3):505–6., , .
Craniofacial anomalies of the amniotic band syndrome in serial clinical cases. Plast Reconstr Surg
2004;113(6):1556–62., , .
Congenital malformations in twins. Am J Hum Genet
pathogenesis and prevention of neural tube defects. Congenit Anom (Kyoto)
Neural tube defects among twin births. Am J Hum Genet
Congenital malformations in twins. A population study. Acta Genet Med Gemellol (Roma), 1986;35:167–78.
International study of sex ratio and twining of neural tube defects. Teratology
L. Monozygotic twinning as a congenital defect and congenital defects in monozygotic twins. Fetal Diagn Ther
Twinning and anencephaly. Ann Hum Biol
disorders and maternal risk factors associated with neural tube defects (v). Taiwan J Obstet Gynecol
Epidemiologic and genetic aspects of spina bifida and other neural tube defects. Dev Disabil Res Rev
Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects. Birth Defects Res A
Human neural tube defects: developmental biology, epidemiology and genetics. Neurotoxicol Teratol