Book contents
- Fetal and Neonatal Brain Injury
- Fetal and Neonatal Brain Injury
- Copyright page
- Contents
- Contributors
- Preface
- Section 1 Epidemiology, Pathophysiology, and Pathogenesis of Fetal and Neonatal Brain Injury
- Section 2 Pregnancy, Labor, and Delivery Complications Causing Brain Injury
- Section 3 Diagnosis of the Infant with Brain Injury
- Chapter 16 Clinical Manifestations of Hypoxic-Ischemic Encephalopathy
- Chapter 17 The Use of EEG and aEEG in Assessing the Term and Preterm Brain
- Chapter 18 Neuroimaging in the Evaluation of Pattern and Timing of Fetal and Neonatal Brain Abnormalities
- Chapter 19 Light-Based Assessment of the Brain
- Chapter 20 Placental Pathology and the Etiology of Fetal and Neonatal Brain Injury
- Chapter 21 Timing Perinatal Hypoxic-Ischemic Brain Injury
- Section 4 Specific Conditions Associated with Fetal and Neonatal Brain Injury
- Index
- References
Chapter 16 - Clinical Manifestations of Hypoxic-Ischemic Encephalopathy
from Section 3 - Diagnosis of the Infant with Brain Injury
Published online by Cambridge University Press: 13 December 2017
Book contents
- Fetal and Neonatal Brain Injury
- Fetal and Neonatal Brain Injury
- Copyright page
- Contents
- Contributors
- Preface
- Section 1 Epidemiology, Pathophysiology, and Pathogenesis of Fetal and Neonatal Brain Injury
- Section 2 Pregnancy, Labor, and Delivery Complications Causing Brain Injury
- Section 3 Diagnosis of the Infant with Brain Injury
- Chapter 16 Clinical Manifestations of Hypoxic-Ischemic Encephalopathy
- Chapter 17 The Use of EEG and aEEG in Assessing the Term and Preterm Brain
- Chapter 18 Neuroimaging in the Evaluation of Pattern and Timing of Fetal and Neonatal Brain Abnormalities
- Chapter 19 Light-Based Assessment of the Brain
- Chapter 20 Placental Pathology and the Etiology of Fetal and Neonatal Brain Injury
- Chapter 21 Timing Perinatal Hypoxic-Ischemic Brain Injury
- Section 4 Specific Conditions Associated with Fetal and Neonatal Brain Injury
- Index
- References
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- Fetal and Neonatal Brain Injury , pp. 247 - 257Publisher: Cambridge University PressPrint publication year: 2017
References
Finer, NN, Robertson, CM, Peters, KL, et al. Factors affecting outcome in hypoxic-ischemic encephalopathy in term infants. Am J Dis Child 1983; 137: 21–5.Google Scholar
Finer, NN, Robertson, CM, Richards, RT, et al. Hypoxic–ischemic encephalopathy in term neonates: perinatal factors and outcome. J Pediatr 1981; 98: 112–17.Google Scholar
Mizrahi, EM, Kellaway, P. Characterization and classification of neonatal seizures. Neurology 1987; 37: 1837–44.CrossRefGoogle ScholarPubMed
Roland, EH, Hill, A. Clinical aspects of perinatal hypoxic-ischemic brain injury. Semin Pediatr Neurol 1995; 2:57–71.Google Scholar
Vannucci, R. Hypoxic-ischemic encephalopathy. Am J Perinatol 2000; 17: 113–20.CrossRefGoogle ScholarPubMed
Blair, E, Stanley, FJ. Intrapartum asphyxia: a rare cause of cerebral palsy. J Pediatr 1988; 112: 515–19.Google Scholar
Nelson, KB, Ellenberg, JH. Antecedents of cerebral palsy: multivariate analysis of risk. N Engl J Med 1986; 315: 81–6.CrossRefGoogle ScholarPubMed
Nelson, KB. What proportion of cerebral palsy is related to birth asphyxia? J Pediatr 1988; 112: 572–4.CrossRefGoogle ScholarPubMed
Naeye, RL, Peters, EC. Antenatal hypoxia and low IQ values. Am J Dis Child 1987; 141: 50–4.Google ScholarPubMed
Cowan, F, Rutherford, M, Groenendaal, F, et al. Origin and timing of brain lesions in term infants with neonatal encephalopathy. Lancet 2003; 361: 736–42.Google Scholar
Levene, MI, Grindulis, H, Sands, C, et al. Comparison of two methods of predicting outcome in perinatal asphyxia. Lancet 1986; 1: 67–9.Google ScholarPubMed
Sarnat, HB, Sarnat, MS. Neonatal encephalopathy following fetal distress: a clinical and electroencephalographic study. Arch Neurol 1976; 33: 696–705.CrossRefGoogle ScholarPubMed
Shankaran, S, Laptook, AR, Ehrenkranz, RA, et al. Whole-body hypothermia for neonates with hypoxic–ischemic encephalopathy. N Engl J Med 2005; 353: 1574–84.Google Scholar
de Vries, L, Jongmans, MJ. Long-term outcome after neonatal hypoxic-ischaemic encephalopathy Arch Dis Child Fetal Neonatal Ed 2010; 95: F220–4.CrossRefGoogle ScholarPubMed
Mwaniki, MK, Atieno, M, Lawn, JE, Newton, CRJ. Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review. Lancet 2012; 279: 445–52.Google Scholar
Shankaran, S, Laptook, AR, Tyson, JE, et al. Evolution of encephalopathy during whole body hypothermia for neonatal hypoxic-ischemic encephalopathy. J Pediatr 2012; 160: 567–72.e3Google Scholar
Merchant, N, Azzopardi, D. Early predictors of outcome in infants treated with hypothermia for hypoxic-ischemic encephalopathy. Dev Med Child Neurol 2015; 57(Suppl. 3): 8–16.CrossRefGoogle Scholar
Ramasawmy, V, Horton, J, Vandermeer, B, et al. Systematic review of biomarkers of brain injury in term neonatal encephalopathy. Pediatr Neurol 2009; 40: 215–26.Google Scholar
Chalak, LF, Sánchez, PJ, Adams-Huet, B, et al. Biomarkers for severity of neonatal hypoxic-ischemic encephalopathy and outcomes in newborns receiving hypothermia therapy. J Pediatr 2014; 164: 468–74.Google Scholar
Takeuchi, T, Watanabe, K. The EEG evolution and neurological prognosis of neonates with perinatal hypoxia. Brain Dev 1989; 11: 115–20.CrossRefGoogle ScholarPubMed
Scher, MS, Painter, MJ, Bergman, I, et al. EEG diagnosis of neonatal seizures: clinical correlations and outcome. Pediatr Neurol 1989; 5: 17–24.CrossRefGoogle ScholarPubMed
Toet, MC, Hellström-Westas, L, Groenendaal, F, et al. Amplitude integrated EEG 3 and 6 hours after birth in full term neonates with hypoxicischemic encephalopathy. Arch Dis Child Fetal Neonatal Ed 1999; 81: F19–23.Google Scholar
Van Laerhoven, H, de Haan, TR, Offriga, M, et al. Prognostic tests in term neonates with hypoxic-ischemic encephalopathy: a systematic review. Pediatrics 2013 131: 88–98.Google Scholar
Scalais, E, François-Adant, A, Nuttin, C, et al. Multimodality evoked potentials as a prognostic tool in term asphyxiated newborns. Electroencephalogr Clin Neurophysiol 1998; 108: 199–207Google Scholar
Kuenzle, C, Baenziger, O, Martin, E, et al. Prognostic value of early MR imaging in term infants with severe perinatal asphyxia. Neuropediatrics 1994; 25: 191–200.CrossRefGoogle Scholar
Baenziger, O, Martin, E, Steinlin, M, et al. Early pattern recognition in severe perinatal asphyxia: a prospective MRI study. Neuroradiology 1993; 35: 437–42.CrossRefGoogle ScholarPubMed
Triulzi, F, Parazzini, C, Righini, A. Patterns of damage in the mature neonatal brain. Pediatr Radiol 2006; 36: 608–20.Google Scholar
Miller, SP, Ramaswamy, V, Michelson, D, et al. Patterns of brain injury in term neonatal encephalopathy. J Pediatr 2005; 146: 153–60.Google Scholar
Chau, V, Poskitt, KJ, Dunham, CP, et al. Magnetic resonance imaging in the encephalopathic term newborn. Curr Pediatr Rev 2014; 10: 28–36.Google Scholar
Hüppi, PS, Murphy, B, Maier, SE, et al. Microstructural brain development after perinatal cerebral white matter injury assessed by diffusion tensor magnetic resonance imaging. Pediatrics 2001; 107: 455–60.CrossRefGoogle ScholarPubMed
Robertson, RL, Ben-Sira, L, Barnes, PD, et al. MR line-scan diffusion-weighted imaging of term neonates with perinatal brain ischemia. Am J Neuroradiol 1999; 20: 658–70.Google Scholar
Myer, JE. Uber die Lokalisation frühkindlicher Hirnshäden in arteriellen Grenzgebieten. Arch Psychiatr Zeitschr Neurol 1953; 190: 328–41.Google Scholar
Volpe, JJ, Herscovitch, P, Perlman, JM, et al. Positron emission tomography in the asphyxiated term newborn: parasagittal impairment of cerebral blood flow. Ann Neurol 1985; 17: 287–96.Google Scholar
Volpe, JJ, Pasternak, JF. Parasagittal cerebral injury in neonatal hypoxic-ischemic encephalopathy: clinical and neuroradiological features. J Pediatr 1979; 91: 472–6.Google Scholar
Friede, RL. Developmental Neuropathology, 2nd edn. New York: Springer-Verlag, 1989.CrossRefGoogle Scholar
Voit, T, Lemburg, P, Neuen, E, et al. Damage of thalamus and basal ganglia in asphyxiated full-term neonates. Neuropediatrics 1987; 18: 176–81.Google Scholar
Johnston, MV, Hoon, AH. Possible mechanisms in infants for selective basal ganglia damage from asphyxia, kernicterus, or mitochondrial encephalopathies. J Child Neurol 2000; 15: 588–91.Google Scholar
Malamud, N, Hirano, A. Atlas of Neuropathology, 2nd edn. Berkeley:University of California Press, 1974.Google Scholar
Gilles, FH. Hypotensive brain stem necrosis: selective symmetrical necrosis of tegmental neuronal aggregates following cardiac arrest. Arch Pathol 1969; 88: 32–41.Google ScholarPubMed
Roland, EH, Hill, A, Norman, MG, et al. Selective brainstem injury in an asphyxiated newborn. Ann Neurol 1988; 23: 89–92.Google Scholar
Pasternak, JF, Gorey, MT. The syndrome of acute near-total intrauterine asphyxia in the term infant. Pediatr Neurol 1998; 18: 391–8.Google Scholar
Natsume, J, Watanabe, K, Kuno, K, et al. Clinical, neurophysiologic, and neuropathological features of an infant with brain damage of total asphyxia type (Myers). Pediatr Neurol 1995; 13: 61–4.CrossRefGoogle ScholarPubMed
Barmada, MA, Moossy, J, Shuman, RM. Cerebral infarcts with arterial occlusion in neonates. Ann Neurol 1979; 6: 495–502.CrossRefGoogle ScholarPubMed
Banker, BQ. Cerebral vascular disease in infancy and childhood. I. Occlusive vascular disease. J Neuropathol Exp Neurol 1961; 20: 127–40.Google Scholar
Koelfen, W, Freund, M, Varnholt, V. Neonatal stroke involving the middle cerebral artery in term infants: clinical presentation, EEG and imaging studies, and outcome. Dev Med Child Neurol 1995; 37: 204–12.Google Scholar
Levine, SC, Huttenlocher, P, Banich, MT, et al. Factors affecting cognitive function of hemiplegic children. Dev Med Child Neurol 1987; 29: 27–35.Google Scholar
Rivkin, MJ, Anderson, ML, Kaye, EM. Neonatal idiopathic cerebral venous thrombosis: an unrecognized cause of transient seizures or lethargy. Ann Neurol 1992; 32: 51–6.Google Scholar
Wong, VK, LeMesurier, J, Franceschini, R, et al. Cerebral venous thrombosis as a cause of neonatal seizures. Pediatr Neurol 1987; 3: 235–7.CrossRefGoogle ScholarPubMed
Banker, BQ, Larroche, JC. Periventricular leukomalacia of infancy. Arch Neurol 1962; 7: 386–410.CrossRefGoogle ScholarPubMed
Guzzetta, F, Shackleford, GD, Volpe, S, et al. Periventricular intraparenchymal echodensities in the premature newborn: critical determination of neurologic outcome. Pediatrics 1986; 78: 995–1006.CrossRefGoogle ScholarPubMed
Fawer, CL, Calame, A, Perentes, E, et al. Periventricular leukomalacia: a correlation study between real-time ultrasound and autopsy findings. Neuroradiology 1985; 27: 292–300.Google Scholar
Trounce, JQ, Rutter, N, Levene, MI. Periventricular leucomalacia and intraventricular haemorrhage in the preterm neonate. Arch Dis Child 1986; 16: 1196–202.Google Scholar
Trounce, JQ, Shaw, DE, Leverne, MI, et al. Clinical risk factors and periventricular leucomalacia. Arch Dis Child 1988; 63: 17–22.Google Scholar
Sarkar, S, Shankaran, S, Laptook, AR et al. Screening cranial imaging at multiple time points improves cystic periventricular leukomalacia detection. Am J Perinatol 2015; 32 (epub ahead of print).Google Scholar
De Vries, LS, Connell, JA, Dubowitz, LMS, et al. Neurological, electrophysiological and MRI abnormalities in infants with extensive cystic leukomalacia. Neuropediatrics 1987; 18: 61–6.Google Scholar
Dolfin, T, Skidmore, MB, Fong, KW, et al. Incidence, severity, and timing of subependymal and intraventricula hemorrhages in preterm infants born in a perinatal unit as detected by serial real-time ultrasound. Pediatrics 1983; 71: 541–6.Google Scholar
Enzmann, D, Murphy-Irwin, K, Stevenson, D, et al. The natural history of subependymal germinal matrix hemorrhage. Am J Perinatol 1985; 2: 123–33.Google Scholar
Scher, MS, Wright, FS, Lockman, LA, et al. Intraventricular haemorrhage in the full-term neonate. Arch Neurol 1982; 39: 769–72.Google Scholar
Volpe, JJ. Intracranial hemorrhage:subdural, primary subarachnoid, cerebellar, intraventricular (term infant), and miscellaneous. In Neurology of the Newborn, 5th edn. Philadelphia: Saunders. 2008: 483–516.CrossRefGoogle Scholar
Bouwer, AJ, Groenendaal, F, Benders, MJ, de Vries, LS. Early and late complications of germinal matrix-intraventricular haemorrhage in the preterm infant: what is new? Neonatology 2014; 106: 296–303.Google Scholar