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  • Print publication year: 2013
  • Online publication date: June 2014


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Ben-Menachem E, Biton V, Jatuzis D, Abdul-Khalil B, Doty P, Rudd GD. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 2007; 48: 1308–1317.
Beyreuther BK, Freitag J, Heers C, Krebsfanger N, Scharfenecker U, Stohr T. Lacosamide: a review of preclinical properties. CNS Drug Reviews 2007; 13: 21–42.
Biton V, Rosenfeld WE, Whitesides J, Fountain NB, Vaiciene N, Rudd GD. Intravenous lacosamide as replacement of oral lacosamide in patients with partial-onset seizures. Epilepsia 2008; 49: 418–424.
Halasz P, Kalviainen R, Mazurkiewicz-Beldzinska M, Rosenow F, Doty P, Hebert D, Sullivan T, on behalf of the SP755 Study Group. Adjunctive lacosamide for partial-onset seizures: efficacy and safety results from a randomized controlled study. Epilepsia 2009; 50: 443–453.
Höfler J, Trinka E. Lacosamide as a new treatment option in status epilepticus. Epilepsia 2013; 53: 393–404.
Kellinghaus C, Berning S, Besselmann M. Intravenous lacosamide as successful treatment for nonconvulsive status epilepticus after failure of first-line therapy. Epilepsy & Behavior 2009; 14: 429–431.
Miro J, Toledo M, Santamarina E, Ricciardi AC, Villanueva V, Pato A, Ruiz J, Juvany R, Falip M. Efficacy of intravenous lacosamide as add-on treatment in refractory status epilepticus: a multicentric prospective study. Seizure 2013; 22: 77–79.
Novy J, Pastsalos PN, Sander JW, Sisodiya SM. Lacosamide neurotoxicity associated with concomitant use of sodium channel-blocking antiepileptic drugs: A pharmacodynamic interaction? Epilepsy & Behavior 2011; 20: 20–23.
Nunes VD, Sawer L, Neilson J, Sarri G, Cross JH. Profile of lacosamide and its long-term treatment of epilepsy: a prospective from the updated NICE guidelines. Neuropsychiatric Disease and Treatment 2013; 9: 467–476.
Patsalos PN, Berry DJ. Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate. Expert Opinion in Pharmacotherapy 2012; 13: 699–715.
Verrotti A, Loiacono G, Pizzolorusso A, Parisi P, Bruni O, Luchetti A, Zamponi N, Cappanera S, Grosso S, Kluger G, Janello C, Franzoni E, Elia M, Spalice A, Coppola G, Striano P, Pavone P, Savasta S, Viri M, Romeo A, Aloisi P, Gobbi G, Ferretti A, Cusmai R, Curatolo P. Lacosamide in paediatric and adult patients: comparison of efficacy and safety. Seizure 2013; 22: 210–216.