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Brivaracetam

Published online by Cambridge University Press:  01 June 2018

Philip N. Patsalos  and
Erik K. St Louis
Philip N. Patsalos
Affiliation:
UCL Institute for Neurology
Erik K. St Louis
Affiliation:
Mayo Clinic
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The Epilepsy Prescriber's Guide to Antiepileptic Drugs , pp. 19 - 27
Publisher: Cambridge University Press
Print publication year: 2018

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References

Suggested Reading

Biton, V, Berkovic, SF, Abou-Khalil, B, Sperling, MR, Johnson, ME, Lu, S. Brivaracetam as adjunctive treatment for uncontrolled partial epilepsy in adults: a phase III randomized, double blind, placebo-controlled trial. Epilepsia 2014; 55: 57–66.CrossRefGoogle ScholarPubMed
Coppola, G, Iapadre, G, Operto, FF, Verrotti, A. New developments in the management of partial-onset epilepsy: role of brivaracetam. Drug Design Development and Therapy 2017; 11: 643–657.CrossRefGoogle ScholarPubMed
Klein, P, Biton, V, Dilley, D, Barnes, M, Schiemann, J, Lu, S. Safety and tolerability of adjunctive brivaracetam as intravenous infusion or bolus in patients with epilepsy. Epilepsia 2016; 57: 1130–1138.CrossRefGoogle ScholarPubMed
Klein, P, Schiemann, J, Sperling, MR, Whitesides, J, Liang, W, Stalvey, T, Brandt, C, Kwan, P. A randomized, double-blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial-onset seizures. Epilepsia 2015; 56: 1890–1898.CrossRefGoogle ScholarPubMed
Klitgaard, H, Matagne, A, Nicolas, JM, Gillard, M, Lamberty, Y, De Ryck, M, Kaminski, RM, Leclercq, K, Niespodziany, I, Wilff, C, Wood, M, Hannestad, J, Kervyn, S, Kenda, B. Brivaracetam: rationale for dicovery and preclinical profile of a sellective SV2A ligand for epilepsy treatment. Epilepsia 2016; 57: 538–548.CrossRefGoogle Scholar
Kruithof, AC, Watanabe, S, Peeters, PA, de Kam, ML, Zuiker, RG, Stevens, J, van Gerven, JM, Stockis, A. Pharmacological interactions between brivaracetam and ethanol in healthy males. Journal of Psychopharmacology 2017; 31: 915–926.CrossRefGoogle ScholarPubMed
Kwan, P, Trinka, E, Van Paesschen, W, Johnson, ME, Lu, S. Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial. Epilepsia 2014; 55: 38–46.CrossRefGoogle ScholarPubMed
Lattanzi, S, Cagnetti, C, Foschi, N, Provinciali, L, Silvestrini, M. Brivaracetam add-on for refractory focal epilepsy: a systematic review and meta-analysis. Neurology 2016; 86: 1344–1352.CrossRefGoogle ScholarPubMed
Ma, J, Huang, S, You, C. Adjunctive brivaracetam for patients with refractory partial seizures: a meta-analysis of randomized placebo-controlled trials. Epilepsy Research 2015; 114: 59–65.CrossRefGoogle ScholarPubMed
Ryvlin, P, Werhahn, KJ, Blaszczyk, B, Johnson, ME, Lu, S. Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: results from a double-blind, randomized, placebo-controlled trial. Epilepsia 2014; 55: 47–56.CrossRefGoogle ScholarPubMed
Schoemaker, R, Wade, JR, Stockis, A. Brivaracetam population pharmacokinetics in children with epilepsy aged 1 month to 16 years. European Journal of Clinical Pharmacology 2017; 73: 727–733.CrossRefGoogle ScholarPubMed
Stockis, A, Sargentini-Maier, ML, Brodie, MJ. Pharmacokinetic interaction between brivaracetam on carbamazepine in adult patients with epilepsy, with and without valproate co-administration. Epilepsy Research 2016; 128: 163–168.CrossRefGoogle ScholarPubMed
Toledo, M, Whitesides, J, Schiemann, J, Johnson, ME, Eckhardt, K, McDonough, B, Borghs, S, Kwan, P. Safety, tolerability, and seizure control during long-term treatment with adjunctive brivaracetam for partial-onset seizures. Epilepsia 2016; 57: 1139–1151.CrossRefGoogle ScholarPubMed

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