Book contents
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Prologue
- Introduction
- 1 The Case of Black Sweat
- 2 A Case of Hives That Wouldn't Go Away
- 3 The Painful Bath
- 4 A Shower of Hives
- 5 A Premenstrual Rash
- 6 Uncombable Hair
- 7 The Man Who Couldn't Sweat
- 8 Scratch Blisters
- 9 Skin Deep Photography
- 10 The Bug That Never Was
- 11 Blue Spots
- 12 White Spots
- 13 Same Place, Next Time Rash
- 14 The Brown Spots That Wouldn't Go Away
- 15 The Case of the Painful Fingertips
- 16 A Strange Sunburn
- 17 A Multiple Personality Dermatitis
- 18 Accidental Hives
- 19 Rotten Fish Odor
- 20 Hormone Blisters
- 21 Flower Shop Itch
- 22 “Stress and a Penny” Hives
- 23 The Case of Unilateral Wrinkles
- 24 Fiery Red Legs
- 25 Painful Feet
- 26 Hot Flashes and Cold Cream
- 27 The Blisters and the Skin Test
- 28 A Chilling Pain
- 29 Rough Skin and Sore Throats
- 30 The Premenstrual Purple Chin
- 31 Nine Year Hives
- 32 Golf Course Dermatitis
- 33 The Secret Message
- 34 Herpes Gladiatorum
- 35 Sunshine Allergy
- 36 L'homme Rouge
- 37 Rings of Rash
- 38 The Breasts That Never Stopped Growing
- 39 The Minister's Hives
- 40 Hardened Skin
- 41 Battery Blisters
- 42 Swollen Lips
- 43 The Worm from Outer Space
- 44 A New Light on Psoriasis
- 45 Black and Blue Spots
- 46 The Emergency Room Itch
- 47 The Sleeper
- 48 A Crazy Rash
- 49 Bald Spots
- 50 The Dog Died
- 51 The Abacus Tumor
- 52 No Spit
- 53 The Smell of Burnt Toast
- 54 The Twenty-Three Year Itch
- 55 The Mysterious Treatment
- 56 The Creeping Acne Cyst
- 57 Our First Case
- 58 A Strange Case of Acne
- 59 The Case of the Glass Eye
- 60 The Hand Eczema Caper
- 61 The Sore That Would Never Heal
- 62 Black Blisters
- References
- Index
47 - The Sleeper
Published online by Cambridge University Press: 23 November 2009
- Frontmatter
- Contents
- Preface
- Acknowledgments
- Prologue
- Introduction
- 1 The Case of Black Sweat
- 2 A Case of Hives That Wouldn't Go Away
- 3 The Painful Bath
- 4 A Shower of Hives
- 5 A Premenstrual Rash
- 6 Uncombable Hair
- 7 The Man Who Couldn't Sweat
- 8 Scratch Blisters
- 9 Skin Deep Photography
- 10 The Bug That Never Was
- 11 Blue Spots
- 12 White Spots
- 13 Same Place, Next Time Rash
- 14 The Brown Spots That Wouldn't Go Away
- 15 The Case of the Painful Fingertips
- 16 A Strange Sunburn
- 17 A Multiple Personality Dermatitis
- 18 Accidental Hives
- 19 Rotten Fish Odor
- 20 Hormone Blisters
- 21 Flower Shop Itch
- 22 “Stress and a Penny” Hives
- 23 The Case of Unilateral Wrinkles
- 24 Fiery Red Legs
- 25 Painful Feet
- 26 Hot Flashes and Cold Cream
- 27 The Blisters and the Skin Test
- 28 A Chilling Pain
- 29 Rough Skin and Sore Throats
- 30 The Premenstrual Purple Chin
- 31 Nine Year Hives
- 32 Golf Course Dermatitis
- 33 The Secret Message
- 34 Herpes Gladiatorum
- 35 Sunshine Allergy
- 36 L'homme Rouge
- 37 Rings of Rash
- 38 The Breasts That Never Stopped Growing
- 39 The Minister's Hives
- 40 Hardened Skin
- 41 Battery Blisters
- 42 Swollen Lips
- 43 The Worm from Outer Space
- 44 A New Light on Psoriasis
- 45 Black and Blue Spots
- 46 The Emergency Room Itch
- 47 The Sleeper
- 48 A Crazy Rash
- 49 Bald Spots
- 50 The Dog Died
- 51 The Abacus Tumor
- 52 No Spit
- 53 The Smell of Burnt Toast
- 54 The Twenty-Three Year Itch
- 55 The Mysterious Treatment
- 56 The Creeping Acne Cyst
- 57 Our First Case
- 58 A Strange Case of Acne
- 59 The Case of the Glass Eye
- 60 The Hand Eczema Caper
- 61 The Sore That Would Never Heal
- 62 Black Blisters
- References
- Index
Summary
“My skin is becoming stiff,” recounted a forty-three-year-old woman. For the past few months she had noted a woody firmness of the skin on her thighs and there were red patches on her shins which also felt stiff. Her face, hands, and feet were normal. She had always been in good health and blood studies showed only a mild increase in her eosinophilic white cells.
Clinically, we felt she had the hardened skin patches of morphea, the localized form of scleroderma. We attempted to ferret out a cause, with no luck. She was taking no medications. There had been no tick bites or even a leech bite, which had caused morphea in one of our patients. She denied infections or exposure to organic chemicals, such as polyvinyl chloride, known to harden the skin. She also did not take the drug, methysergide, notorious for its ability to indurate connective tissue. She had never had silicone breast implants, which might leak and induce sclerotic skin.
We tried both cortisone and antibiotic therapy without success, as well as topical emollients which were likewise without effect. We were still searching for a cause when the patient came in with the answer and with an apology. She had found the reason in the newspaper, learning that the FDA had banned the sale of the amino acid, tryptophan. This over-the-counter compound used by thousands to combat insomnia and depression was now linked to hundreds of cases of hardening of the skin.
- Type
- Chapter
- Information
- Consultations in DermatologyStudies of Orphan and Unique Patients, pp. 143 - 145Publisher: Cambridge University PressPrint publication year: 2006