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  • Print publication year: 2008
  • Online publication date: September 2015

23 - The use ofconstraint-induced movement therapy (CI therapy) to promote motor recovery following stroke

from Section 5 - Behavioral/ neuropsychological approaches


American Heart Association (2005). Heart and Stroke Statistical Update.
Azrin, N. H., & Holz, W. C. (1996). Punishment. In W. K. Honig (Ed.), Operant Behavior: Areas of Research and Application (pp. 380–447). New York, NY: Appleton-Century-Crofts.
Bach-y-Rita, P. (1993). Recovery from brain damage. Journal of Neurological Rehabilitation, 6, 191–199.
Bach-y-Rita, P., & Bach-y-Rita, E. W. (1990). Biological and psychosocial factors in recovery from brain damage in humans. Canadian Journal of Psychology, 44, 148–165.
Bauder, H., Sommer, M., Taub, E., & Miltner, W. H. R. (1999). Effect of CI therapy on movement-related brain potentials. Psychophysiology, 36, S31.
Butefisch, C., Hummelsheim, H., Densler, P., & Mauritz, K.-H. (1995). Mauritz, K-H. Repetitive training of isolated movements improves the outcome of motor rehabilitation of the centrally paretic hand. Journal of Neurological Science, 130, 59–68.
Catania, A. C. (1998). Learning (4th Edition). Upper Saddle River, NJ: Prentice Hall.
Center for Disease Control and Prevention. (2004). Health, United States. http.//
Dettmers, C., Teske, U., Hamzei, F. et al. (2005). Distributed form of constraint-induced movement therapy improves functional outcome and quality of life after stroke. Archives of Physical Medicine and Rehabilitation, 86, 204–209.
Dobkin, B. H. (1989). Focused stroke rehabilitation programs do not improve outcome. Archives of Neurology and Psychiatry, 46, 701–703.
Duncan, P. W. (1997). Synthesis of intervention trials to improve motor recovery following stroke. Topics in Stroke Rehabilitation, 3, 1–20.
Duncan, P. W., Zorowitz, R., Bates, B. et al. (2005). Management of adult rehabilitation care: a clinical practice guideline. Stroke, 36, e100–e143.
Elbert, T., Pantev, C., Wienbruch, C., Rockstroh, B., & Taub, E. (1995). Increased use of the left hand in string players associated with increased cortical representation of the fingers. Science, 220, 21–23.
Estes, W. K. (1944). An experimental study of punishment. Psychological Monographs, 57, (Serial No. 263).
Flor, H., Elbert, T., Knecht, S. et al. (1995). Phantom limb pain as a perceptual correlate of massive reorganization in upper limb amputees. Nature, 375, 482–484.
Franz, S. I., Scheetz, M. E., & Wilson, A. A. (1915). The possibility of recovery of motor functioning in long-standing hemiplegia. Journal of the American Medical Association, 65, 2150–2154.
Halberstam, J. L., Zaretsky, H. H., Brucker, B. S., & Guttman, A. (1971). Avoidance conditioning of motor responses in elderly brain-damaged patients. Archives of Physical Medicine and Rehabilitation, 52, 318–328.
Hesse, S., Bertelt, C., Schaffrin, A., Malezic, M. S., & Mauritz, K.-H. (1994). Restoration of gait in nonambulatory hemiparetic patients by treadmill training with partial body-weight support. Archives of Physical Medicine and Rehabilitation, 75, 1087–1093.
Ince, L. P. (1969). Escape and avoidance conditioning of response in the plegic arm of stroke patients: a preliminary study. Psychonomic Science, 16, 49–50.
Jenkins, W. M., Merzenich, M. M., Ochs, M. T., T., A., & Guic-Robles, E. (1990). Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation. Journal of Neurophysiology, 63, 82–104.
Knapp, H. D., Taub, E., & Berman, A. J. (1958). Effect of deafferentiation on a conditioned avoidance response. Science, 128, 842–843.
Kolb, B. (2003). Overview of cortical plasticity and recovery from brain injury. Physical Medicine and Rehabilitation Clinics of North America, 14, Suppl. 1, S7–S25.
Kopp, B., Kunkel, A., Flor, H. et al. (1997). The Arm Motor Ability Test (AMAT): Reliability, validity and sensitivity to change. Archives of Physical Medicine and Rehabilitation, 78, 615–620.
Kopp, B., Kunkel, A., Mühlnickel, W. et al. (1999). Plasticity in the motor system correlated with therapy-induced improvement of movement in human stroke patients. NeuroReport, 10, 807–810.
Kunkel, A., Kopp, B., Muller, G. et al. (1999). Constraint-induced movement therapy for motor recovery in chronic stroke patients. Archives of Physical Medicine and Rehabilitation, 80, 624–628.
Lashley, K. S. (1924). Studies of cerebral function in learning: V. The retention of motor areas in primates. Archives of Neurology and Psychiatry, 12, 249–276.
Levy, C. E., Nichols, D. S., Schmalbrock, P. M., Keller, P., & Chakers, D. W. (2001). Functional MRI evidence of cortical reorganization in upper-limb stroke hemiplegia treated with constraint-induced movement therapy. American Journal of Physical Medicine and Rehabilitation, 80, 4–12.
Liepert, J., Bauder, H., Sommer, M. et al. (1998). Motor cortex plasticity during constraint-induced movement therapy in chronic stroke patients. Neuroscience Letters, 250, 5–8.
Liepert, J., Bauder, H., Miltner, W. H. R., Taub, E., & Weiller, C. (2000). Treatment-induced cortical reorganization after stroke in humans. Stroke, 31, 1210–1216.
Lum, P. S., Taub, E., Schwandt, D. et al. (2004). Automated constraint-induced therapy extension (AutoCITE) for movement deficits after stroke. Journal of Rehabilitation Research and Development, 41, 249–257.
Lum, P. S., Uswatte, G., Taub, E., Hardin, P., & Mark, V. W. (2006). A tele-rehabilitation approach to delivery of constraint-induced movement therapy. Journal of Rehabilitation Research and Development, 43, 391–399.
Mark, V. W., & Taub, E. (2004). Constraint-induced movement therapy for chronic stroke hemiparesis and other disabilities. Restorative Neurology and Neuroscience, 22, 317–336.
McCulloch, K., Cook, E. W. I., Fleming, W. C. et al. (1988). A reliable test of upper extremity ADL function. Archives of Physical Medicine and Rehabilitation, 69, 755.
Miltner, W. H. R., Bauder, H., Sommer, M., Dettmers, C., & Taub, E. (1999). Effects of constraint-induced movement therapy on patients with chronic motor deficits after stroke: a replication. Stroke, 30, 586–592.
Miltner, W. H. R., Balzer, C., & Taub, E. (submitted). CI therapy treatment outcome tracked by substantial changes in functional magnetic resonance imaging.
Morgan, W. G. (1974). The shaping game: a teaching technique. Behavior Therapy, 5, 271–272.
Morris, D., & Taub, E. (2001). The constraint-induced therapy approach to restoring function after neurological injury. Topics in Stroke Rehabilitation, 8, 16–30.
Morris, D. M., Crago, J. E., DeLuca, S. C., Pidikiti, R. D., & Taub, E. (1997). Constraint-induced (CI) movement therapy for motor recovery after stroke. Neurorehabitation, 9, 29–43.
Morris, D. M., Uswatte, G., Crago, J. E., Cook, E. W. III., & Taub, E. (2001). The reliability of the Wolf Motor Function Test for assessing upper extremity function after stroke. Archives of Physical Medicine and Rehabilitation, 82, 750–755.
Mott, F. W., & Sherrington, C. S. (1895). Experiments upon the influence of sensory nerves upon movement and nutrition of the limbs. Proceedings of the Royal Society of London, 57, 481–488.
Nudo, R. J., Wise, B. M., SiFuentes, F., & Milliken, G. W. (1996). Neural substrates for the effects of rehabilitative training on motor recovery following ischemic infarct. Science, 272, 1791–1794.
Ostendorf, C. G., & Wolf, S. L. (1981). Effect of forced use of the upper extremity of a hemiplegic patient on changes in function. Physical Therapy, 61, 1022–1028.
Panyan, M. V. (1980). How to use Shaping. Lawrence, KS: H & H Enterprises.
Pons, T. P., Garraghty, A. K., Ommaya, A. K. et al. (1991). Massive cortical reorganization after sensory deafferentiation in adult macaques. Science, 252, 1857–1860.
Recanzone, G. H., Jenkins, W. M., & Merzenich, M. M. (1992a). Progressive improvement in discriminative abilities in adult owl monkeys performing a tactile frequency discrimination task. Journal of Neurophysiology, 67, 1015–1030.
Recanzone, G. H., Merzenich, M. M., & Jenkins, W. M. (1992b). Frequency discrimination training engaging a restricted skin surface results in an emergence of a cutaneous response zone in cortical area 3a. Journal of Neurophysiology, 67, 1057–1070.
Recanzone, G. H., Merzenich, M. M., Jenkins, W. M., Grajski, A., & Dinse, H. R. (1992c). Topographic reorganization of the hand representation in area 3b of owl monkeys trained in a frequency discrimination task. Journal of Neurophysiology, 67, 1031–1056.
Skinner, B. F. (1938). The Behavior of Organisms. New York, NY: Appleton-Century-Crofts.
Skinner, B. F. (1968). The Technology of Teaching. New York, NY: Appleton-Century-Crofts.
Sterr, A., Müller, M. M., Elbert, T. et al. (1998). Changed perceptions in Braille readers. Nature, 391, 134–135.
Sterr, A., Elbert, T., Berthold, I. et al. (2002). CI therapy in chronic hemiparesis: the more the better? Archives of Physical Medicine and Rehabilitation, 83, 1374–1377.
Taub, E. (1980). Somatosensory deafferentation research with monkeys: implications for rehabilitation medicine. In L. P. Ince (Eds.), Behavioral Psychology in Rehabilitation Medicine: Clinical Applications (pp. 371–401). New York, NY: Williams & Wilkins.
Taub, E., Miller, N. E., Novack, T. A. et al. (1993). Technique to improve chronic motor deficit after stroke. Archives of Physical Medicine and Rehabilitation, 74, 347–354.
Taub, E., Crago, J. E., Burgio, L. D. et al. (1994). An operant approach to rehabilitation medicine: overcoming learned nonuse by shaping. Journal of the Experimental Analysis of Behavior, 61, 281–293.
Taub, E., Crago, J. E., & Uswatte, G. (1998). Constraint-induced movement therapy: a new approach to treatment in physical rehabilitation. Rehabilitation Psychology, 43, 152–170.
Taub, E., Uswatte, G., & Pidikiti, R. (1999). Constraint-induced movement therapy: a new family of techniques with broad application to physical rehabilitation – a clinical review. Journal of Rehabilitation Research and Development, 36, 237–251.
Taub, E., Uswatte, G., & Elbert, T. (2002). New treatments in neurorehabilitation founded on basic research. Neuroscience, 3, 226–236.
Taub, E., Lum, P. S., Hardin, P., Mark, V. W., & Uswatte, G. (2005). AutoCITE: automated delivery of CI therapy with reduced effort by therapists. Stroke, 36, 1301–1304.
Taub, E., Uswatte, G., King, D. K. et al. (2006). A placebo controlled trial of constraint-induced movement therapy for upper extremity after stroke. Stroke, 37, 1045–1049.
Twitchell, T. E. (1954). Sensory factors in purposive movement. Journal of Neurophysiology, 17, 239–254.
Uswatte, G., & Taub, E. (1999). Constraint-induced movement therapy: new approaches to outcome measurement in rehabilitation. In D. T. Stuss, G. Winocur, & I. H. Robertson (Eds.), Cognitive Neurorehabilitation (pp. 214–229). Cambridge, UK: Cambridge University Press.
Uswatte, G., & Taub, E. (2005). Implications of the learned nonuse formulation for measuring rehabilitation outcomes: lessons from constraint-induced movement therapy. Rehabilitation Psychology, 50, 34–42.
Uswatte, G., Taub, E., Morris, D. M., Vignolo, M., & McCulloch, K. (2005). Reliability and validity of the Upper-extremity Motor Activity Log-14 for measuring real-world arm use. Stroke, 36, 2493–2496.
Uswatte, G., Taub, E., Morris, D. M., Barman, J., & Crago, J. (2006). Contribution of the shaping and restraint components of constraint-induced movement therapy to treatment outcome. Neurorehabilitation, 21, 147–156.
Wittenberg, G. F., Chen, R., Ishii, K. et al. (2003). Constraint-induced movement therapy in stroke: magnetic-stimulation motor maps and cerebral activation. Neurorehabilitation and Neural Repair, 17, 48–57.
Wolf, S. L., Lecraw, D. E., Barton, L. A., & Jann, B. B. (1989). Forced use of hemiplegic upper extremities to reverse the effect of learned nonuse among chronic stroke and head-injured patients. Experimental Neurology, 104, 104–132.
Wolf, S. L., Catlin, P. A., Ellis, M. et al. (2001). Assessing the Wolf Motor Function Test as an outcome measure for research with patients post-stroke. Stroke, 32, 1635–1639.
Wolf, S. L., Winstein, C., Miller, J. P. et al. (2006). The Extremity Constraint Induced Therapy Evaluation (EXCITE) trial for patients with sub-acute stroke. Journal of the American Medical Association, 296, 2095–2104.