Book contents
- Frontmatter
- Contents
- Preface
- Part I Introduction
- Part II Poststroke depression
- 5 Diagnosis of depression
- 6 Prevalence of depressive disorders
- 7 Phenomenology and specificity of depressive symptoms
- 8 Natural course of depression
- 9 Delayed-onset depression
- 10 Relationship to lesion location
- 11 Relationship of depression to cerebral dominance and structural asymmetries
- 12 Relationship of depression to bilateral hemisphere brain injury
- 13 Relationship of depression to physical impairment
- 14 Relationship to cognitive impairment and treatment
- 15 Relationship of aphasia to depression
- 16 Relationship of depression to social functioning
- 17 Relationship to premorbid risk factors
- 18 Mortality and treatment
- 19 Suicidal thoughts and plans
- 20 Biological markers
- 21 Mechanisms of poststroke depression
- 22 Treatment of poststroke depression
- 23 Prevention of poststroke depression
- Part III Poststroke mania
- Part IV Poststroke anxiety disorders
- Part V Other poststroke disorders
- Index
9 - Delayed-onset depression
from Part II - Poststroke depression
Published online by Cambridge University Press: 01 October 2009
- Frontmatter
- Contents
- Preface
- Part I Introduction
- Part II Poststroke depression
- 5 Diagnosis of depression
- 6 Prevalence of depressive disorders
- 7 Phenomenology and specificity of depressive symptoms
- 8 Natural course of depression
- 9 Delayed-onset depression
- 10 Relationship to lesion location
- 11 Relationship of depression to cerebral dominance and structural asymmetries
- 12 Relationship of depression to bilateral hemisphere brain injury
- 13 Relationship of depression to physical impairment
- 14 Relationship to cognitive impairment and treatment
- 15 Relationship of aphasia to depression
- 16 Relationship of depression to social functioning
- 17 Relationship to premorbid risk factors
- 18 Mortality and treatment
- 19 Suicidal thoughts and plans
- 20 Biological markers
- 21 Mechanisms of poststroke depression
- 22 Treatment of poststroke depression
- 23 Prevention of poststroke depression
- Part III Poststroke mania
- Part IV Poststroke anxiety disorders
- Part V Other poststroke disorders
- Index
Summary
Another issue related to the course of poststroke depression is time of onset of depression. Why do some patients develop depression during the acute poststroke period while other patients develop it several months or even years following stroke. We have recently examined this issue using our group of 142 patients with longitudinal follow-up to determine the frequency of acute- versus delayed-onset major and minor depression during the first 2 years following stroke. The follow-up evaluations were conducted at 3, 6, 12, and 24 months following stroke.
The background characteristics of the patients are shown in Table 9.1. Patients who developed major depression during the acute poststroke period tended to be younger than those who developed delayed-onset major depression, although the age distribution across diagnostic groups was not significantly different. There was no significant difference in the frequency of major versus minor depression among patients with acute- or delayed-onset depression.
There were no significant differences in any of the other background characteristics or previous history of psychiatric disorder. Similarly, there were no significant differences between groups in the use of medications; that is, antihypertensives, steroids, psychotropics, or other drugs. Two of the patients with acute depressions and one with delayed-onset depression were receiving antidepressant medication.
- Type
- Chapter
- Information
- The Clinical Neuropsychiatry of StrokeCognitive, Behavioral and Emotional Disorders following Vascular Brain Injury, pp. 82 - 86Publisher: Cambridge University PressPrint publication year: 2006