A one-size-fits-all approach to pain management is not practical, nor ethically justifiable. This chapter explains pain management using the case study of a 61-year-old woman with metastatic colon cancer and intractable abdominal pain, as an example. Technological advancements within science and medicine have enabled prolongation of the lifespan for those patients with incurable diseases. Interventional techniques may be especially useful because of their capacity to effectively reduce pain, make patients more amenable to other therapeutics, and enhance patients' quality of life. Interventional pain management techniques and integrative pain medicine are underutilized, due to misperceptions by hospital operators and insurance companies about cost effectiveness. Employment of collaborative interventional techniques, however, has been shown to be both cost and time effective. Physicians should advocate policy development that is directed toward developing and enabling the profession and practice of pain/palliative care.