Dionysius's career attests to the increasing fragility of Roman society around 400, the wealth that might be made through medicine, and, most important, the intertwining of medicine and Christianity. The arrival of Christianity in 313 as an approved religion of the Roman state, and its increasing dominance, introduced new relationships into medicine and natural science, in both the Latin West and the Greek-speaking East. An increasing Galenism is most evident in the development of medical encyclopedias. Only a handful of works by Galen and Hippocrates were translated into Latin, along with portions of Oribasius and Paul of Aegina, in all probability in the region of Ravenna. Leaving aside the Ravenna commentaries on Galen and Hippocrates, which were present in a few major Benedictine monasteries in Italy discussions of medical theory in the manner of Galen are replaced by summaries of basic facts necessary for establishing the framework for medical practice.