Safety of medical treatments implies all their side and long-term effects on patients. With reference to ART, subjects involved are mothers and their children. Since the early application of IVF, operators have agreed on the importance of monitoring these new techniques in order to build and maintain trust towards them. Collecting data regarding assisted reproduction techniques worldwide is of the utmost usefulness to ensure safety and quality of treatments provided, to detect potential problems, as well as to implement practices aimed at reducing risks and improving outcomes.
Nowadays, well-functioning registries have been set up in most countries. Regulations and guidelines for the monitoring of all clinical and laboratory aspects of assisted reproduction techniques have been issued, also based on data collected so far.
Currently available evidence should be the basis for a further improvement of medical and laboratory practices.