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Chapter 21 - Anemia of Chronic Inflammation

from Section 3, Part E - Hypoplastic Anemias

Published online by Cambridge University Press:  18 April 2018

Edward J. Benz, Jr.
Affiliation:
Dana Farber Cancer Institute
Nancy Berliner
Affiliation:
Brigham and Women's Hospital, Boston
Fred J. Schiffman
Affiliation:
Children's Hospital, Boston
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Summary

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Type
Chapter
Information
Anemia
Pathophysiology, Diagnosis, and Management
, pp. 150 - 155
Publisher: Cambridge University Press
Print publication year: 2017

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References

Weiss, G, Goodnough, LT. Anemia of chronic disease. N Engl J Med. 2005; 352(10):10111023.Google Scholar
Cartwright, GE, Lauritsen, MA, Jones, PJ, Merrill, IM, Wintrobe, MM. The anemia of infection. I. Hypoferremia, hypercupremia, and alterations in porphyrin metabolism in patients. J Clin Invest. 1946; 25(1):6580.Google Scholar
Blanc, B, et al. Nutritional anaemias. Report of a WHO scientific group. World Health Organization Technical Report Series. 1968; 405:537.Google Scholar
Yip, R, Dallman, PR. The roles of inflammation and iron deficiency as causes of anemia. Am J Clin Nutr. 1988; 48(5):12951300. Epub 1988/11/01.Google Scholar
Guralnik, JM, Eisenstaedt, RS, Ferrucci, L, Klein, HG, and Woodman, RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004; 104(8):22632268.Google Scholar
Masson, C. Rheumatoid anemia. Joint Bone Spine. 2011; 78(2):131137. Epub 2010/09/21.Google Scholar
Wilson, A, Reyes, E, Ofman, J. Prevalence and outcomes of anemia in inflammatory bowel disease: a systematic review of the literature. Am J Med. 2004; 116 Suppl 7A:44S49S.Google Scholar
Piagnerelli, M, Vincent, JL. The use of erythropoiesis-stimulating agents in the intensive care unit. Crit Care Clin. 2012; 28(3):345362, v. Epub 2012/06/21.CrossRefGoogle ScholarPubMed
van Iperen, CE, van de Wiel, A, Marx, JJ. Acute event-related anaemia. Br J Haematol. 2001; 115(4):739743. Epub 2002/02/15.CrossRefGoogle ScholarPubMed
Sihler, KC, Napolitano, LM. Anemia of inflammation in critically ill patients. J Intensive Care Med. 2008; 23(5):295302. Epub 2008/08/15.Google Scholar
Baer, AN, Dessypris, EN, Goldwasser, E, Krantz, SB. Blunted erythropoietin response to anaemia in rheumatoid arthritis. Br J Haematol. 1987; 66(4):559564.CrossRefGoogle ScholarPubMed
Means, RT Jr., Krantz, SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood. 1992; 80(7):16391647.CrossRefGoogle ScholarPubMed
Koury, MJ, Ponka, P. New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2004; 24:105131.CrossRefGoogle ScholarPubMed
Cartwright, GE, Lee, GR. The anaemia of chronic disorders. Br J Haematol. 1971; 21(2):147152. Epub 1971/08/01.Google Scholar
Nemeth, E, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004; 306(5704):20902093.Google Scholar
Qiao, B, et al. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metab. 2012; 15(6):918924. Epub 2012/06/12.CrossRefGoogle ScholarPubMed
Ross, SL, et al. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metab. 2012; 15(6):905917. Epub 2012/06/12.Google Scholar
Ganz, T, Nemeth, E. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematol Am Soc Hematol Educ Program. 2011; 2011:538542. Epub 2011/12/14.Google Scholar
Schwoebel, F, et al. The effects of the anti-hepcidin Spiegelmer NOX H94 on inflammation-induced anemia in cynomolgus monkeys. Blood. 2013; 121(12):23112315. Epub 2013/01/26.CrossRefGoogle ScholarPubMed
Wang, W, Knovich, MA, Coffman, LG, Torti, FM, Torti, SV. Serum ferritin: past, present and future. Biochim Biophys Acta. 2010; 1800(8):760769. Epub 2010/03/23.CrossRefGoogle ScholarPubMed
Cash, JM, Sears, DA. The anemia of chronic disease: spectrum of associated diseases in a series of unselected hospitalized patients. Am J Med. 1989; 87(6):638644.CrossRefGoogle Scholar
Roy, CN. Anemia of inflammation. Hematology Am Soc Hematol Educ Program. 2010; 30:276280.CrossRefGoogle Scholar
Skikne, BS. Serum transferrin receptor. Am J Hematol. 2008; 83(11):872–85.CrossRefGoogle ScholarPubMed
Marti-Carvajal, AJ, Agreda-Perez, LH, Sola, I, Simancas-Racines, D. Erythropoiesis-stimulating agents for anemia in rheumatoid arthritis. Cochrane Database Syst Rev. 2013; 2:CD000332. Epub 2013/03/02.Google Scholar
Dallman, PR, Yip, R, Johnson, C. Prevalence and causes of anemia in the United States, 1976 to 1980. Am J Clin Nutr. 1984; 39(3):437445. Epub 1984/03/01.Google Scholar
Price, EA, Mehra, R, Holmes, TH, Schrier, SL. Anemia in older persons: etiology and evaluation. Blood Cells Mol Dis. 2011; 46(2):159165. Epub 2011/01/07.Google Scholar
Artz, AS, Thirman, MJ. Unexplained anemia predominates despite an intensive evaluation in a racially diverse cohort of older adults from a referral anemia clinic. J Gerontol A Biol Sci Med Sci. 2011; 66(8):925932. Epub 2011 Jun 9.CrossRefGoogle Scholar
Voulgarelis, M, Kokori, SI, Ioannidis, JP, Tzioufas, AG, Kyriaki, D, Moutsopoulos, HM. Anaemia in systemic lupus erythematosus: aetiological profile and the role of erythropoietin. Ann Rheum Dis. 2000; 59(3):217222.CrossRefGoogle ScholarPubMed
Martinez-Lado, L, et al. Relapses and recurrences in giant cell arteritis: a population-based study of patients with biopsy-proven disease from northwestern Spain. Medicine (Baltimore). 2011; 90(3):186193. Epub 2011/04/23.Google Scholar
Vincent, JL, et al. Anemia and blood transfusion in critically ill patients. J Am Med Assoc. 2002; 288(12):14991507. Epub 2002/09/24.CrossRefGoogle ScholarPubMed

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