Skip to main content Accessibility help
×
Home
Hostname: page-component-99c86f546-md8df Total loading time: 1.058 Render date: 2021-12-02T06:33:12.086Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Book contents

Chapter 25 - Non-hormonal Treatments for Menopausal Symptoms

Published online by Cambridge University Press:  18 June 2020

Nicholas Panay
Affiliation:
Queen Charlotte's & Chelsea Hospital, London
Paula Briggs
Affiliation:
Liverpool Women's NHS Foundation Trust
Gabor T. Kovacs
Affiliation:
Monash University, Victoria
Get access

Summary

There are a number of symptoms associated with perimenopause and decreasing estrogen levels, although some women will experience none of these. They include hot flashes and night sweats (vasomotor symptoms), vaginal symptoms, depression, anxiety, irritability and mood swings (psychological effects), joint pains, migraines or headaches, sleeping problems and urinary incontinence.

Type
Chapter
Information
Managing the Menopause , pp. 254 - 263
Publisher: Cambridge University Press
Print publication year: 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Avis, NE, Crawford, SL, Greendale, G, Bromberger, JT, Everson-Rose, SA, Gold, EB, Hess, R, Joffe, H, Kravitz, HM, Tepper, PG, Thurston, RC1, Study of Women’s Health Across the Nation. Duration of menopausal vasomotor symptoms over the menopause transition. JAMA Intern Med 2015 Apr;175(4):531–9.CrossRefGoogle Scholar
Freedman, RR. Biochemical: metabolic, and vascular mechanisms in menopausal hot flashes. Fertil Steril 1998;70:332–7.CrossRefGoogle ScholarPubMed
Freedman, RR, Krell, W. Reduced thermoregulatory null zone in postmenopausal women with hot flashes. Am J Obstet Gynecol 1999;181:6670.CrossRefGoogle ScholarPubMed
Nelson, HD, Vesco, KK, Haney, E, et al. Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis. JAMA 2006;295:2057–71.CrossRefGoogle ScholarPubMed
Rada, G, Capurro, D, Pantoja, T, et al. Non-hormonal interventions for hot flushes in women with a history of breast cancer. Cochrane Database Syst Rev 2010;9:CD004923.Google Scholar
Speroff, L, Gass, M, Constantine, GD, Olivier, S, Study 315 Investigators. Efficacy and tolerability of desvenlafaxine succinate treatment for menopausal vasomotor symptoms: a randomized controlled trial. Obstet Gynecol 2008;111:7787.CrossRefGoogle ScholarPubMed
Archer, DF, Dupont, CM, Constantine, GD, Pickar, JH, Olivier, S, Study 319 Investigators. Desvenlafaxine for the treatment of vasomotor symptoms associated with menopause: a double-blind, randomized, placebo-controlled trial of efficacy and safety. Am J Obstet Gynecol 2009;200:238e1e10.CrossRefGoogle ScholarPubMed
Lethaby, A, Marjoribanks, J, Kronenberg, F, et al. Phytoestrogens for vasomotor menopausal symptoms. Cochrane Database Syst Rev 2007;4:CD001395.Google Scholar
Wong, VC, Lim, CE, Luo, X, Wong, WS. Current alternative and complementary therapies used in menopause. Gynecol Endocrinol 2009;25:166–74.CrossRefGoogle Scholar
Newton, KM, Reed, SD, LaCroix, AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2005;145:869–79.Google Scholar
Barton, DL, Loprinzi, CL, Quella, SK, et al. Prospective evaluation of vitamin E for hot flashes in breast cancer survivors. J Clin Oncol 1998;16:495500.CrossRefGoogle ScholarPubMed
Kroenke, CH, Caan, BJ, Stefanick, ML, Anderson, G, Brzyski, R, Johnson, KC, LeBlanc, E, Lee, C, La Croix, AZ, Park, HL, Sims, ST, Vitolins, M, Wallace, R. Effects of a dietary intervention and weight change on vasomotor symptoms in the Women’s Health Initiative. Menopause 2012 Sep;19(9):980–8.Google ScholarPubMed
Thurston, RC, Ewing, LJ, Low, CA, et al. Behavioral weight loss for the management of menopausal hot flashes: a pilot study. Menopause 2015;22:5965.CrossRefGoogle ScholarPubMed
Huang, AJ, Subak, LL, Wing, R, et al. An intensive behavioral weight loss intervention and hot flushes in women. Arch Intern Med 2010;170:1161–7.CrossRefGoogle ScholarPubMed
Sassarini, J, Fox, H, Ferrell, W, Sattar, N, Lumsden, MA. Vascular function and cardiovascular risk factors in women with severe flushing. Clin Endocrinol 2011 Jan;74(1):97103.CrossRefGoogle ScholarPubMed
Daley, A, Stokes-Lampard, H, Mutrie, N, MacArthur, C. Exercise for vasomotor menopausal symptoms. Cochrane Database Syst Rev 2007;4:CD006108.Google Scholar
Bailey, TG, Cable, NT, Aziz, N, et al. Exercise training reduces the acute physiological severity of post-menopausal hot flushes. J Physiol 2016;594:657–67.CrossRefGoogle ScholarPubMed
Cramer, H, Rabsilber, S, Lauche, R, Kümmel, S, Dobos, G. Yoga and meditation for menopausal symptoms in breast cancer survivors – a randomized controlled trial. Cancer 2015 Jul 1;121(13):2175–84.CrossRefGoogle ScholarPubMed
Cramer, H, Peng, W, Lauche, R. Yoga for menopausal symptoms—a systematic review and meta-analysis. Maturitas 2018;109:1325.CrossRefGoogle ScholarPubMed
Ayers, B, Smith, M, Hellier, J, et al. Effectiveness of group and self-help cognitive behavior therapy in reducing problematic menopausal hot flushes and night sweats (MENOS 2): a randomized controlled trial. Menopause 2012;19:749–59.Google ScholarPubMed
Mann, E, Smith, MJ, Hellier, J, et al. Cognitive behavioural treatment for women who have menopausal symptoms after breast cancer treatment (MENOS 1): a randomised controlled trial. Lancet Oncol 2012;13:309–18.CrossRefGoogle ScholarPubMed
van Gastel, P, Kallewaard, J-W, van der Zanden, M, de Boer, H. Stellate-ganglion block as a treatment for severe postmenopausal flushing. Climacteric 2013;16:41–7.Google Scholar
Walega, DR, Rubvvbounoussin, LH, Banuvar, S, et al. Effects of stellate ganglion block on vasomotor symptoms: findings from a randomized controlled clinical trial in postmenopausal women. Menopause 2014;21(8):807–14.Google ScholarPubMed
Prague, JK, Roberts, RE, Comninos, AN, Clarke, S, Jayasena, CN, Nash, Z, Doyle, C, Papadopoulou, DA, Bloom, SR, Mohideen, P, Panay, N, Hunter, MS, Veldhuis, JD, Webber, LC, Huson, L, Dhillo, WS. Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet 2017;389(10081):1809–20.CrossRefGoogle ScholarPubMed

Send book to Kindle

To send this book to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Send book to Dropbox

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Dropbox.

Available formats
×

Send book to Google Drive

To send content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about sending content to Google Drive.

Available formats
×