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Chapter 3 - Priming solutions for cardiopulmonary bypass circuits

Published online by Cambridge University Press:  05 December 2015

Sunit Ghosh
Papworth Hospital, Cambridge
Florian Falter
Papworth Hospital, Cambridge
Albert C. Perrino, Jr
Yale University, Connecticut
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Publisher: Cambridge University Press
Print publication year: 2015

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Suggested Further Reading

Cooley, DA, Beall, AC, Grondin, P. Open heart operations with disposable oxygenators, 5% dextrose prime, and normothermia. Surgery 1962; 52:713–19
Fang, WC, Helm, RE, Krieger, KH et al. Impact of minimum hematocrit during cardiopulmonary bypass on mortality in patients undergoing coronary artery surgery. Circulation 1997; 96 (9 suppl): II–194–9
Gurbuz, H, Durukan, A, Salman, N et al. Hydroxyethyl starch 6%, 130/0.4 vs. a balanced crystalloid solution in cardiopulmonary bypass priming: a randomized, prospective study. Journal of Cardiothoracic Surgery 2013, 8: 71
Harris, EA, Seelye, ER, Barratt-Boyes, BG. Respiratory and acid-base changes during CPB in man. Br J Anaesth 1970; 42: 912–21
Hoeft, A, Korb, H, Mehlhorn, U et al. Priming of cardiopulmonary bypass with human albumin or ringer lactate: effect on colloid osmotic pressure and extravascular lung water. Br J Anaesth 1991; 66:7380
Lilley, A. The selection of priming fluids for cardiopulmonary bypass in the UK and Ireland. Perfusion 2002; 17:315319
Liskaser, FJ, Bellomo, R, Hayhoe, M et al. Role of pump prime in etiology and pathogenesis of cardiopulmonary bypass – associated acidosis. Anesthesiology 2000; 93:1170–73
Marelli, D, Paul, A, Samson, R et al. Does the addition of albumin to the prime solution in cardiopulmonary bypass affect outcome? A prospective randomized study. J Thorac Cardiovasc Surg 1989; 98(5 Pt1):751756
Murphy, G, Hessel, E, Groom, R. Optimal perfusion during cardiopulmonary bypass: an evidence-based approach. Anesth Analg 2009;108(5):1394–417
Myburgh, J Finfer, S, Bellomo, R, et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med 2012 367: 19011911
Paone, G, Silverman, N. The paradox of on bypass transfusion thresholds in blood conservation. Circulation 1997; 96(suppl II):II 205208
Perner, A,Haase, N, Guttormsen, A, et al.; Scandinavian Critical Care Trials Group. Hydroxyethyl starch 130/0.42 versus Ringer’s acetate in severe sepsis. N Engl J Med 2012; 367:124–34.
Rawn, JD. Blood transfusion in cardiac surgery: a silent epidemic revisited. Circulation 2007; 116(22):2523–4
Riegger, L, Voepel-Lewis, T, Kulik, T et al. Albumin versus crystalloid prime solution for cardiopulmonary bypass in young children. Crit Care Med 2002; 30(12):2649–54
Rosengart, TK, DeBois, WJ, Helm, RE. Retrograde autologous priming (RAP) for cardiopulmonary bypass: a safe and effective means of decreasing hemodilution and transfusion requirements. J Thorac Cardiovasc Surg 1998; 115(2):426–38
Russell, JA, Navickis, RJ, Wilkes, MM. Albumin versus crystalloid for pump priming in cardiac surgery: a meta-analysis of controlled trials. J Cardiothorac Vasc Anesth 2004; 18(4):429–37
Skhirtladze, K, Base, E, Lassnigg, A, et al. Comparison of the effects of albumin 5%, hydroxyethyl starch 130/0.4 6%, and Ringer’s lactate on blood loss and coagulation after cardiac surgery. Br J Anaesth 2014; 112(2):255–64
Sun, P, Ji, B, Sun, Y, et al. Effects of retrograde autologous priming on blood transfusion and clinical outcomes in adults: a meta-analysis. Perfusion 2013; 28( 3):238–43
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