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20A - Endometriosis Should Be Suppressed for 6–12 Weeks before Frozen Embryo Transfer

For

from Section III - The Best Policy

Published online by Cambridge University Press:  25 November 2021

By
Hassan N Sallam
Edited by
Roy Homburg ,
Adam H. Balen  and
Robert F. Casper
Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

Various management options exist for the treatment of endometriosis-associated infertility. These include medical treatment, surgical treatment and a combination of both. When these options fail to produce a pregnancy, assisted reproduction is resorted to, ranging from intrauterine insemination (IUI) for minimal and mild cases of endometriosis to IVF and ICSI for those who do not achieve a pregnancy with IUI and for more advanced cases [1]. However, the clinical outcomes of IVF in patients with endometriosis-associated infertility seem to be diminished in comparison to patients suffering from tubal or unexplained infertility.

Type
Chapter
Information
50 Big Debates in Reproductive Medicine , pp. 106 - 108
Publisher: Cambridge University Press
Print publication year: 2021

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References

Sallam, HN, Garcia-Velasco, JA, Dias, S, Arici, A. Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004635.CrossRefGoogle Scholar
Senapati, S, Sammel, MD, Morse, C, Barnhart, KT. Impact of endometriosis on in vitro fertilization outcomes: an evaluation of the Society for Assisted Reproductive Technologies Database. Fertil Steril. 2016 July;106(1):164–71.CrossRefGoogle Scholar
de Ziegler, D, Gayet, V, Aubriot, FX, et al. Use of oral contraceptives in women with endometriosis before assisted reproduction treatment improves outcomes. Fertil Steril. 2010 Dec;94(7):2796–9.CrossRefGoogle ScholarPubMed
Georgiou, EX, Melo, P, Baker, PE, et al. Long-term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosis. Cochrane Database Syst Rev. 2019 Nov 20;2019(11).Google ScholarPubMed
Van der Houwen, LEE, Lier, MCI, Schreurs, AMF, et al. Continuous oral contraceptives versus long-term pituitary desensitization prior to IVF/ICSI in moderate to severe endometriosis: study protocol of a non-inferiority randomized controlled trial. Hum Reprod Open. 2019 Feb 23;2019(1):hoz001.CrossRefGoogle ScholarPubMed

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