Hostname: page-component-8448b6f56d-wq2xx Total loading time: 0 Render date: 2024-04-23T06:34:03.370Z Has data issue: false hasContentIssue false

Sodium, added sugar and saturated fat intake in relation to mortality and CVD events in adults: Canadian National Nutrition Survey linked with vital statistics and health administrative databases

Published online by Cambridge University Press:  08 April 2022

Mahsa Jessri*
Affiliation:
Food, Nutrition and Health Program, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, BC, Canada Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada Health Analysis Division, Statistics Canada, Government of Canada, Ottawa, ON, Canada School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada
Deirdre Hennessey
Affiliation:
Health Analysis Division, Statistics Canada, Government of Canada, Ottawa, ON, Canada
Anan Bader Eddeen
Affiliation:
Institute for Clinical Evaluative Sciences, Ottawa, ON, Canada
Carol Bennett
Affiliation:
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada Institute for Clinical Evaluative Sciences, Ottawa, ON, Canada
Zefeng Zhang
Affiliation:
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
Quanhe Yang
Affiliation:
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
Claudia Sanmartin
Affiliation:
Health Analysis Division, Statistics Canada, Government of Canada, Ottawa, ON, Canada
Douglas Manuel
Affiliation:
Centre for Health Services and Policy Research, School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada Department of Family Medicine, University of Ottawa, Ottawa, ON, Canada C.T. Lamont Primary Health Care Research Centre Program, Bruyère Research Institute, Ottawa, ON, Canada
*
* Corresponding author: Mahsa Jessri, email mahsa.jessri@ubc.ca

Abstract

This study aimed to determine whether higher intakes of Na, added sugars and saturated fat are prospectively associated with all-cause mortality and CVD incidence and mortality in a diverse population. The nationally representative Canadian Community Health Survey-Nutrition 2004 was linked with the Canadian Vital Statistics – Death Database and the Discharge Abstract Database (2004–2011). Outcomes were all-cause mortality and CVD incidence and mortality. There were 1722 mortality cases within 115 566 person-years of follow-up (median (interquartile range) of 7·48 (7·22–7·70) years). There was no statistically significant association between Na density or energy from saturated fat and all-cause mortality or CVD events for all models investigated. The association of usual percentage of energy from added sugars and all-cause mortality was significant in the base model with participants consuming 11·47 % of energy from added sugars having 1·34 (95 % CI 1·01, 1·77) times higher risk of all-cause mortality compared with those consuming 4·17 % of energy from added sugars. Overall, our results did not find statistically significant associations between the three nutrients and risk of all-cause mortality or CVD events at the population level in Canada. Large-scale linked national nutrition datasets may not have the discrimination to identify prospective impacts of nutrients on health measures.

Type
Research Article
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of The Nutrition Society

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Milajerdi, A, Djafarian, K & Shab-Bidar, S (2019) Dose–response association of dietary sodium intake with all-cause and cardiovascular mortality: a systematic review and meta-analysis of prospective studies. Public Health Nutr 22, 295306.CrossRefGoogle ScholarPubMed
De Souza, RJ, Mente, A, Maroleanu, A, et al. (2015) Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies. Bmj 351, h3978.CrossRefGoogle ScholarPubMed
Tasevska, N, Park, Y, Jiao, L, et al. (2014) Sugars and risk of mortality in the NIH-AARP Diet and Health Study. Am J Clin Nutr 99, 10771088.CrossRefGoogle ScholarPubMed
Grandjean, AC (2012) Dietary intake data collection: challenges and limitations. Nutr Reviews 70, S101S4.CrossRefGoogle ScholarPubMed
Schoeller, DA (1995) Limitations in the assessment of dietary energy intake by self-report. Metabolism 44, 1822.CrossRefGoogle ScholarPubMed
Health Canada (2019) Healthy Eating Strategy. https://food-guide.canada.ca/en/ (accessed April 2019).Google Scholar
Institute of Medicine (US) (2005) Panel on Dietary Reference Intakes for Electrolytes and Water. DRI, Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: National Academies Press.Google Scholar
Moshfegh, AJ, Rhodes, DG, Baer, DJ, et al. (2008) The US Department of Agriculture Automated Multiple-Pass Method reduces bias in the collection of energy intakes. Am J Clin Nutr 88, 324332.CrossRefGoogle ScholarPubMed
Moshfegh, AJ, Borrud, L, Perloff, B, et al. (1999) Improved method for the 24-hour dietary recall for use in national surveys. FASEB J 13, A603.Google Scholar
Tooze, JA, Midthune, D, Dodd, KW, et al. (2006) A new statistical method for estimating the usual intake of episodically consumed foods with application to their distribution. J Am Diet Assoc 106, 15751587.CrossRefGoogle ScholarPubMed
Brisbois, TD, Marsden, SL, Anderson, GH, et al. (2014) Estimated intakes and sources of total and added sugars in the Canadian diet. Nutrients 6, 18991912.CrossRefGoogle ScholarPubMed
Shields, M, Connor Gorber, S, Janssen, I, et al. (2011) Bias in self-reported estimates of obesity in Canadian health surveys: an update on correction equations for adults. Health Rep 22, 3545.Google ScholarPubMed
Sanmartin, C, Decady, Y, Trudeau, R, et al. (2016) Linking the Canadian Community Health Survey and the Canadian Mortality Database: an enhanced data source for the study of mortality. Health Rep 27, 1018.Google Scholar
National Cancer Institute (2018) Usual Dietary Intakes: SAS Macros for the NCI Method. https://epi.grants.cancer.gov/diet/usualintakes/macros.html (accessed June 2018).Google Scholar
National Cancer Institute (2018) Usual Dietary Intakes: The NCI Method. https://epi.grants.cancer.gov/diet/usualintakes/method.html (accessed May 2018).Google Scholar
Kipnis, V, Midthune, D, Buckman, DW, et al. (2009) Modeling data with excess zeros and measurement error: application to evaluating relationships between episodically consumed foods and health outcomes. Biometrics 65, 10031010.CrossRefGoogle ScholarPubMed
Jessri, M, Lou, WY & L’Abbe, MR (2016) Evaluation of different methods to handle misreporting in obesity research: evidence from the Canadian national nutrition survey. Br J Nutr 115, 147159.CrossRefGoogle ScholarPubMed
Institute of Medicine (2005) Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein and Amino Acids. Washington, DC: National Academy Press.Google Scholar
Yang, Q, Liu, T, Kuklina, EV, et al. (2011) Sodium and potassium intake and mortality among USA adults: prospective data from the Third National Health and Nutrition Examination Survey. Arch Intern Med 171, 11831191.CrossRefGoogle ScholarPubMed
Yang, Q, Zhang, Z, Gregg, EW, et al. (2014) Added sugar intake and cardiovascular diseases mortality among USA adults. JAMA Intern Med 174, 516524.CrossRefGoogle Scholar
Allison, DB, Heo, M, Flanders, DW, et al. (1997) Examination of ‘early mortality exclusion’ as an approach to control for confounding by occult disease in epidemiologic studies of mortality risk factors. Am J Epidemiol 146, 672680.CrossRefGoogle ScholarPubMed
Rao, JNK, Wu, CFJ & Yue, K (1992) Some recent work on resampling methods for complex surveys. Surv Methodol 18, 209217.Google Scholar
USA Department of Agriculture/Health and Human Services (2020) Dietary Guidelines for Americans 2020–2025. https://www.dietaryguidelines.gov/sites/default/files/2020–12/Dietary_Guidelines_for_Americans_2020–2025.pdf (accessed May 2021).Google Scholar
He, FJ & MacGregor, GA (2009) A comprehensive review on salt and health and current experience of worldwide salt reduction programmes. J Hum Hypertens 23, 363384.CrossRefGoogle ScholarPubMed
Sacks, FM, Svetkey, LP, Vollmer, WM, et al. (2001) Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group. N Engl J Med 344, 310.CrossRefGoogle ScholarPubMed
Graudal, NA, Galloe, AM & Garred, P (1998) Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride: a meta-analysis. JAMA 279, 13831391.Google ScholarPubMed
Cook, NR, Obarzanek, E, Cutler, JA, et al. (2009) Joint effects of sodium and potassium intake on subsequent cardiovascular disease: the Trials of Hypertension Prevention follow-up study. Arch Intern Med 169, 3240.CrossRefGoogle ScholarPubMed
Strazzullo, P, D’Elia, L, Kandala, NB, et al. (2009) Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies. BMJ 339, b4567.CrossRefGoogle ScholarPubMed
Kagan, A, Popper, JS, Rhoads, GG, et al. (1985) Dietary and other risk factors for stroke in Hawaiian Japanese men. Stroke 16, 390396.CrossRefGoogle ScholarPubMed
Tunstall-Pedoe, H, Woodward, M, Tavendale, R, et al. (1997) Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish Heart Health Study: cohort study. BMJ 315, 722729.CrossRefGoogle ScholarPubMed
Alderman, MH, Cohen, H & Madhavan, S (1998) Dietary sodium intake and mortality: the National Health and Nutrition Examination Survey (NHANES I). Lancet 351, 781785.CrossRefGoogle ScholarPubMed
Cohen, HW, Hailpern, SM & Alderman, MH (2008) Sodium intake and mortality follow-up in the Third National Health and Nutrition Examination Survey (NHANES III). J Gen Intern Med 23, 12971302.CrossRefGoogle ScholarPubMed
Cohen, HW, Hailpern, SM, Fang, J, et al. (2006) Sodium intake and mortality in the NHANES II follow-up study. Am J Med 119, 275.e7e14.CrossRefGoogle ScholarPubMed
Cook, NR, Appel, LJ & Whelton, PK (2016) Sodium intake and all-cause mortality over 20 years in the trials of hypertension prevention. J Am Coll Cardiol 68, 16091617.CrossRefGoogle ScholarPubMed
Umesawa, M, Iso, H, Date, C, et al. (2008) Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer Risks. Am J Clin Nutr 88, 195202.CrossRefGoogle ScholarPubMed
He, J, Ogden, LG, Vupputuri, S, et al. (1999) Dietary sodium intake and subsequent risk of cardiovascular disease in overweight adults. JAMA 282, 20272034.CrossRefGoogle ScholarPubMed
Nagata, C, Takatsuka, N, Shimizu, N, et al. (2004) Sodium intake and risk of death from stroke in Japanese men and women. Stroke 35, 15431547.CrossRefGoogle ScholarPubMed
Takachi, R, Inoue, M, Shimazu, T, et al. (2010) Consumption of sodium and salted foods in relation to cancer and cardiovascular disease: the Japan Public Health Center-based Prospective Study. Am J Clin Nutr 91, 456464.CrossRefGoogle ScholarPubMed
Tuomilehto, J, Jousilahti, P, Rastenyte, D, et al. (2001) Urinary sodium excretion and cardiovascular mortality in Finland: a prospective study. Lancet 357, 848851.CrossRefGoogle ScholarPubMed
Ramsden, CE, Zamora, D, Majchrzak-Hong, S, et al. (2016) Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968–73). BMJ 353, i1246.CrossRefGoogle ScholarPubMed
Steur, M, Johnson, L, Sharp, SJ, et al. (2021) Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: findings from the EPIC-CVD case-cohort study across nine European Countries. J Am Heart Assoc 10, e019814.CrossRefGoogle ScholarPubMed
World health Organization (2018) Draft Guidelines on Saturated Fatty Acid and Trans-Fatty Acid Intake for Adults and Children. Geneva: WHO.Google Scholar
Jessri, M, Wolfinger, RD, Lou, WY, et al. (2017) Identification of dietary patterns associated with obesity in a nationally representative survey of Canadian adults: application of a priori, hybrid, and simplified dietary pattern techniques. Am J Clin Nutr 105, 669684.CrossRefGoogle Scholar
Jessri, M, Ng, AP & L’Abbe, MR (2017) Adapting the Healthy Eating Index 2010 for the Canadian Population: Evidence from the Canadian National Nutrition Survey. Nutrients 9, 910.CrossRefGoogle ScholarPubMed
Tooze, JA, Kipnis, V, Buckman, DW, et al. (2010) A mixed-effects model approach for estimating the distribution of usual intake of nutrients: the NCI method. Stat Med 29, 28572868.Google ScholarPubMed
Willett, W (2013) Nutritional Epidemiology, 3rd ed. Oxford: Oxford University Press.Google Scholar
Satija, A, Yu, E, Willett, WC, et al. (2015) Understanding nutritional epidemiology and its role in policy. Adv Nutr 6, 518.Google ScholarPubMed
Liu, S, Munasinghe, LL, Ohinmaa, A, et al. (2020) Added, free and total sugar content and consumption of foods and beverages in Canada. Health Rep 31, 1424.Google ScholarPubMed
Kotchen, TA & Kotchen, JM (1997) Dietary sodium and blood pressure: interactions with other nutrients. Am J Clin Nutr 65, 708s711s.CrossRefGoogle ScholarPubMed
Jessri, M & L’abbe, MR (2015) The time foran updated Canadian Food Guide has arrived. Appl Physiol Nutr Metab 40(8), 854857. doi: 10.1139/apnm-2015-0046. Epub 2015 Jul 9.CrossRefGoogle Scholar
Supplementary material: File

Jessri et al. supplementary material

Jessri et al. supplementary material 1

Download Jessri et al. supplementary material(File)
File 185.9 KB
Supplementary material: File

Jessri et al. supplementary material

Jessri et al. supplementary material 2

Download Jessri et al. supplementary material(File)
File 185.8 KB