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Precipitation elasticity is an efficient index to quantify the sensitivity of streamflow to precipitation changes in watersheds. It provides us with a tool to understand the historical and predicted changes in streamflow, which is key to assess the impact of climate change on water resources. This chapter provides the details of three frequently used methods for estimating precipitation elasticity of streamflow and a case study on the temporal and spatial variability of precipitation elasticity and runoff coefficient in 164 watersheds in China. The precipitation elasticity is estimated by a non-parametric estimator in three periods of interest. The results bring evidence of an association between spatiotemporal patterns of streamflow changes and precipitation changes, which suggest that climatic change is a dominant factor of annual streamflow changes in the investigated watersheds. In most watersheds, the precipitation elasticity of streamflow is larger than 1, indicating that a 1 per cent change in annual precipitation would result in more than a 1 per cent change in annual streamflow. The precipitation elasticity in watersheds with a small runoff coefficient is generally larger than that in watersheds with a large runoff coefficient.
Statistical issues are prominent in Alzheimer’s disease (AD) clinical trials due to the enormous challenges in this disease. The complexity of the disease and intervention pathways challenge drug discovery efforts, but measurement and analysis complexities and subjective outcomes also interfere with successful drug development. Variability across disease stage, disease sub-types, comorbidities and concomitant treatments (between-subject), and non-equivalent forms, good and bad days, and rater inconsistencies (within-subject) increase the chance of failure. AD-specific statistical expertise is critical for success, in contrast to most disease areas that require less disease-specific statistical knowledge. Use of global statistical tests and composites, correcting for covariates, and model selection increase the chance of a clearly positive outcome for active treatments and a clearly negative outcome for inactive or harmful treatments.
First-episode psychosis (FEP) is associated with metabolic alterations. However, it is not known if there is heterogeneity in these alterations beyond what might be expected due to normal individual differences, indicative of subgroups of patients at greater vulnerability to metabolic dysregulation.
Methods
We employed meta-analysis of variance, indexed using the coefficient of variation ratio (CVR), to compare variability of the following metabolic parameters in antipsychotic naïve FEP and controls: fasting glucose, glucose post-oral glucose tolerance test (OGTT), fasting insulin, insulin resistance, haemoglobin A1c (HbA1c), total-cholesterol, low-density lipoprotein (LDL)-cholesterol, high-density lipoprotein (HDL)-cholesterol, and triglycerides. Standardised mean difference in metabolic parameters between groups was also calculated; meta-regression analyses examined physiological/demographic/psychopathological moderators of metabolic change.
Results
Twenty-eight studies were analysed (1716 patients, 1893 controls). Variability of fasting glucose [CVR = 1.32; 95% confidence interval (CI) 1.12–1.55; p = 0.001], glucose post-OGTT (CVR = 1.43; 95% CI 1.10–1.87; p = 0.008), fasting insulin (CVR = 1.31; 95% CI 1.09–1.58; p = 0.01), insulin resistance (CVR = 1.34; 95% CI 1.12–1.60; p = 0.001), HbA1c (CVR = 1.18; 95% CI 1.06–1.27; p < 0.0001), total-cholesterol (CVR = 1.15; 95% CI 1.01–1.31; p = 0.03), LDL-cholesterol (CVR = 1.28; 95% CI 1.09–1.50; p = 0.002), and HDL-cholesterol (CVR = 1.15; 95% CI 1.00–1.31; p < 0.05), but not triglycerides, was greater in patients than controls. Mean glucose, glucose post-OGTT, fasting insulin, insulin resistance, and triglycerides were greater in patients; mean total-cholesterol and HDL-cholesterol were reduced in patients. Increased symptom severity and female sex were associated with worse metabolic outcomes.
Conclusions
Patients with FEP present with greater variability in metabolic parameters relative to controls, consistent with a subgroup of patients with more severe metabolic changes compared to others. Understanding determinants of metabolic variability could help identify patients at-risk of developing metabolic syndrome. Female sex and severe psychopathology are associated with poorer metabolic outcomes, with implications for metabolic monitoring in clinical practice.
The fossil record is scarce and incomplete by nature. Animals and ecological processes devour soft tissue and important bony details over time and, when the dust settles, we are faced with a patchy record full of variation. Fossil taxa are usually defined by craniodental characteristics, so unless postcranial bones are found associated with a skull, assignment to taxon is unstable. Naming a locomotor category based on fossil bone morphology by analogy to living hominoids is not uncommon, and when no single locomotor label fits, postcrania are often described as exhibiting a ‘mosaic’ of traits. Here, we contend that the unavoidable variation that characterises the fossil record can be described far more rigorously based on extensive work in human neurobiology and neuroanatomy, movement sciences and motor control and biomechanics research. In neurobiology, degeneracy is a natural mechanism of adaptation allowing system elements that are structurally different to perform the same function. This concept differs from redundancy as understood in engineering, where the same function is performed by identical elements. Assuming degeneracy, structurally different elements are able to produce different outputs in a range of environmental contexts, favouring ecological robusticity by enabling adaptations. Furthermore, as degeneracy extends to genome level, genetic variation is sustained, so that genes which might benefit an organism in a different environment remain part of the genome, favouring species’ evolvability.
The study provides comparative risk analyses of Australia’s three Victorian dairy regions. Historical data were used to identify business risk and financial viability. Multivariate distributions were fitted to the historical price, production, and input costs using copula models, capturing non-linear dependence among the variables. Monte Carlo simulation methods were then used to generate cash flows for a decade. Factors that influenced profitability the most were identified using sensitivity analysis. The dairies in the Northern region have faced water reductions, whereas those of Gippsland and South West have more positive indicators. Our analysis summarizes long-term risks and net farm profits by utilizing survey data in a probabilistic manner.
Vowels are traditionally viewed as one of the two major classes of speech sound. Vowels lack contact between the tongue and the roof of the mouth, and they are normally voiced. Importantly, the speaker receives little proprioceptive feedback from their speech organs, meaning that it is not fully appropriate to define a vowel in terms of place and manner of articulation. Instead, tongue height and advancement are used to describe vowel quality, and auditory features play a more important role in description, e.g. with reference to the Cardinal Vowels system. Vowel categories form a continuum, and this has repercussions in terms of articulatory, auditory and acoustic overlap between contrastive categories and the special role that vowel gradience plays in dialect variation and language change. Other features of vowels stem from the general openness of vocalic articulations. For example, in principle, lip rounding can be combined with any tongue position, and nasality too demonstrates specific patterns that have both phonetic and phonological dimensions. Vowel quantity, or duration, is also used in differing ways by different languages, both phonemically and allophonically.
This chapter provides an overview of the ADEPT planning system that applies the previously discussed principles of effective plan-development, implementation, and evaluation.
The extent of the reduction of maize (Zea mays L.) kernel moisture content through drying is closely related to field temperature (or accumulated temperature; AT) following maturation. In 2017 and 2018, we selected eight maize hybrids that are widely planted in Northeastern China to construct kernel drying prediction models for each hybrid based on kernel drying dynamics. In the traditional harvest scenario using the optimal sowing date (OSD), maize kernels underwent drying from 4th September to 5th October, with variation coefficients of 1.0–1.9. However, with a latest sowing date (LSD), drying occurred from 14th September to 31st October, with variation coefficients of 1.3–3.0. In the changed harvest scenario, the drying time of maize sown on the OSD condition was from 12th September to 9th November with variation coefficients of 1.3–3.0, while maize sown on the LSD had drying dates of 26th September to 28th October with variation coefficients of 1.5–3.6. In the future harvest scenario, the Fengken 139 (FK139) and Jingnongke 728 (JNK728) hybrids finished drying on 20th October and 8th November, respectively, when sown on the OSD and had variation coefficients of 2.7–2.8. Therefore, the maize kernel drying time was gradually delayed and was associated with an increased demand for AT ⩾ 0°C late in the growing season. Furthermore, we observed variation among different growing seasons likely due to differences in weather patterns, and that sowing dates impact variations in drying times to a greater extent than harvest scenarios.
Symmetry: it may be symmetric, mildly asymmetric, or markedly asymmetric. Mild asymmetry of the dominant hemisphere may be physiologic. Continuity: it may be continuous, nearly continuous, discontinuous, or burst-suppressed. Attenuation is the periodic dampening of amplitudes by less than half the remaining background, while suppression is when the amplitude falls below 10 uV. Voltage: it may be normal (above 20 uV), low voltage (20-10 uV), or suppressed (less than 10 uV). Organization: a well-organized background has an anterior-posterior gradient, predominantly alpha frequencies, and a reactive posterior dominant rhythm (PDR). The loss of either or all these features results in a deterioration in background organization. Variability and reactivity: variability refers to spontaneous changes in the background, while variability refers to changes in response to external stimulation. Always specify the stimulation used and advance it in a graded manner. Variability and reactivity of the background are associated with favorable clinical outcomes. Presence of stage II sleep architecture such as spindles and K complexes should be noted
This paper addresses how input variability in the adult phonological system is mastered in the output of young children in Akan, a Kwa language spoken in Ghana, involving variability between labio-palatalized consonants and front rounded vowels. The high-frequency variant involves a complex consonant which is expected to be mastered late, while the low-frequency variant involves a front rounded vowel which is expected to be mastered relatively early. Late mastery of complex consonants was confirmed. The high-frequency labiopalatalized-consonant variant was absent at age 3 and not yet mastered even at age 5. All children produced the easier-to-produce low-frequency front-rounded-vowel variant, most at far greater frequency than in adult speech, implying that a child's output limitations can affect which variant the child targets for production. Modular theories, in which phonological plans reflect only the characteristics of adult input, fail to account for our results. Non-modular theories are implicated.
The 50-year career of Peter Ornstein heralded and reflected major changes in Developmental Psychology. In this commentary, I highlight the importance of the “Cognitive Revolution” for the study of memory development. As his research progressed, Ornstein saw that a fuller understanding of memory development was needed to recognize the role of the classroom environment in shaping cognitive growth. Subsequent research discovered large individual differences in teacher pedagogic activities, the direct impact of teacher behavior on children’s memory development and important child by instruction interactions. Viewed across that 50-year span, Ornstein’s impressive career offers insightful life lessons for those who follow.
The bulk of the work on nonnative speech has focused on average differences between L1 and L2 speakers. However, there is growing evidence that variability also plays an important role in distinguishing L1 from L2 speech. While some studies have demonstrated greater variability for nonnative than native speech, others have demonstrated that under some circumstances, nonnative speech maybe less variable and that variability in nonnative speech may shift as a function of many factors, including task and L1-L2 pairing. In the present study, we ask how variability manifests in L1 and L2 speech by speakers from a variety of language backgrounds. Specifically, we ask whether a speaker whose L1 speaking rate is highly variable is also highly variable in their L2. We also ask whether variability in speaking rate in L1 or L2 differs as a function of task (e.g., read vs. spontaneous speech) and complexity of the task (e.g., more or less complicated reading passages). The results of this study will inform our understanding of the myriad complex factors that influence nonnative speech.
An important objective of research in Second Language Acquisition has been to find a simple and reliable way to quantify second language use. Corpora have provided a crucial source of information for these studies. In spite of many attempts to determine an optimal “yardstick” to measure the quality of second language use, particularly lexical complexity and syntactic complexity, a reliable and widely applicable instrument has not yet been determined. The difficulty in finding a suitable instrument can be accounted for in a complex dynamic systems theory (CDST) approach to second language development. An important starting point of this approach is that every next step in time “is the emergent product of context and history, and no component has causal priority” (Thelen 2005, p. 271). In this paper we illustrate this by using a dense longitudinal corpus of the development of 22 highly similar L2 learners, consisting of 23 weekly measurements. The analysis of these data show convincingly that L2 development is a highly individually owned and nonlinear process. While complexity yardsticks (like MLTU and Guiraud) may seem functional from a group perspective, their application to individual learners is very limited.
The chapter summarises the main arguments and evidence throughout the volume, presenting the case for a broad multidisciplinary perspective on defining, understanding and researching L2 fluency by considering fluency as a dynamic variable in language performance that interacts with cognitive factors as well as with external factors. Main points from research and practice are synthesised evaluating current insights into fluency across cognitive, interactional, pedagogic and assessment domains. We finish by identifying remaining gaps in our understanding of how fluency develops, and how combining research and practice is needed to help understand issues of real-life second language communication.
This chapter discusses two types of descriptive statistics: models of central tendency and models of variability. Models of central tendency describe the location of the middle of the distribution, and models of variability describe the degree that scores are spread out from one another. There are four models of central tendency in this chapter. Listed in ascending order of the complexity of their calculations, these are the mode, median, mean, and trimmed mean. There are also four principal models of variability discussed in this chapter: the range, interquartile range, standard deviation, and variance. For the latter two statistics, students are shown three possible formulas (sample standard deviation and variance, population standard deviation and variance, and population standard deviation and variance estimated from sample data), along with an explanation of when it is appropriate to use each formula. No statistical model of central tendency or variability tells you everything you may need to know about your data. Only by using multiple models in conjunction with each other can you have a thorough understanding of your data.
Previous research has shown that heritage speakers struggle with inflectional morphology. ‘Limitations of online resources’ for processing a non-dominant language has been claimed as one possible reason for these difficulties. To date, however, there is very little experimental evidence on real-time language processing in heritage speakers. Here we report results from a masked priming experiment with 97 bilingual (Turkish/German) heritage speakers and a control group of 40 non-heritage speakers of Turkish examining regular and irregular forms of the Turkish aorist. We found that, for the regular aorist, heritage speakers use the same morphological decomposition mechanism (‘affix stripping’) as control speakers, whereas for processing irregularly inflected forms they exhibited more variability (i.e., less homogeneous performance) than the control group. Heritage speakers also demonstrated semantic priming effects. At a more general level, these results indicate that heritage speakers draw on multiple sources of information for recognizing morphologically complex words.
Iron production has played a part in the history of Africa for more than 2,500 years. The study of this specific human activity has demonstrated its exceptional significance, its historical continuity and an astonishing variability of practice. In Sub-Saharan Africa, metallurgists developed different ways to produce the same material: iron. They multiplied the technical choices to a degree unequalled on other continents. But what is the significance of such extreme diversity? In this chapter, four case studies representing different situations are detailed: in Dendi Country/Benin, where the question of the nature of the raw materials is considered; in Dogon Country/Mali, seven contemporaneous smelting traditions in a limited geographical area; at the Korsimoro site/Burkina Faso, five successive smelting traditions in the same place; and in the Bassar region/Togo, the impact of ancient and intensive iron production on the environment and on the technology. Based on these examples the chapter discusses the interpretation of diversity in terms of the history of technology and population dynamics.
Many emotional experiences such as anxiety and depression are influenced by negative affect (NA). NA has both trait and state features, which play different roles in physiological and mental health. Attending to NA common to various emotional experiences and their trait-state features might help deepen the understanding of the shared foundation of related emotional disorders.
Methods
The principal component of five measures was calculated to indicate individuals' NA level. Applying the connectivity-based correlation analysis, we first identified resting-state functional connectives (FCs) relating to NA in sample 1 (n = 367), which were validated through an independent sample (n = 232; sample 2). Next, based on the variability of FCs across large timescale, we further divided the NA-related FCs into high- and low-variability groups. Finally, FCs in different variability groups were separately applied to predict individuals' neuroticism level (which is assumed to be the core trait-related factor underlying NA), and the change of NA level (which represents the state-related fluctuation of NA).
Results
The low-variability FCs were primarily within the default mode network (DMN) and between the DMN and dorsal attention network/sensory system and significantly predicted trait rather than state NA. The high-variability FCs were primarily between the DMN and ventral attention network, the fronto-parietal network and DMN/sensory system, and significantly predicted the change of NA level.
Conclusions
The trait and state NA can be separately predicted by stable and variable spontaneous FCs with different attentional processes and emotion regulatory mechanisms, which could deepen our understanding of NA.
This essay provides a typology of different ‘Pauls’ in the early centuries (P, HP, HEP, PACTS, CanP), all of which may in some sense be rooted in the inheritance of the genuine letters (HEP), but are interpreted and reshaped in a variety of ways according to the needs, purposes, contexts and talents of early interpreters. It identifies the key elements, practical, technological, bibliographic and hermeneutical, that shaped the interpretation of ‘Paul’ in the early church and enduringly throughout the history of Pauline interpretation that was to follow.
The capacity to sustain attention was explored in a sample of anhedonic subjects according to the Chapman physical anhedonia scale. Sustained attention was determined by studying task-induced changes over the duration of the Eriksen response competition task [Percept. Psychophys. 16 (1974) 143]. Anhedonic subjects had longer reaction times (RTs), but missed no more targets than control subjects. Anhedonic subject RTs got longer with time-on-task (TOT) and displayed greater intra-subject variability. These results confirm those of a previous study indicating that anhedonic subjects may have developed a more conservative response strategy [Psychophysiology 37 (2000) 711] and suggest that this strategy may result in a more rapid decrease in energetical resources. Moreover, the greater intra-subject variability demonstrates the importance of assessing performance over time and its relationship to the variability of responses in the cognitive performance of anhedonic subjects.