Search

Skip to main content Accessibility help

Home
Search

Only show content I have access to (0)

Chapters (1)

Over 3 years (1)

From year:

To year:

Apply

Medicine (1)

hemorheologic factors

Cambridge University Press (1)

View selected items
Save to my bookmarks
Export citations
Download PDF (zip)
Save to Kindle
Save to Dropbox
Save to Google Drive
Save content to
To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to .

To save content items to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Please be advised that item(s) you selected are not available.
You are about to save
Your Kindle email address

Please provide your Kindle email.

@free.kindle.com @kindle.com (service fees apply)

By using this service, you agree that you will only keep content for personal use, and will not openly distribute them via Dropbox, Google Drive or other file sharing services

1 results

58 - BONE DISORDERS AND CEREBROVASCULAR DISEASES
from PART V: - SYSTEMIC DISORDERS THAT ALSO INVOLVE THE CEREBROVASCULAR SYSTEM
- By Natan M. Bornstein, Alexander Y. Gur
Edited by Louis R. Caplan, Julien Bogousslavsky
Book:

Uncommon Causes of Stroke

Published online:

06 January 2010

Print publication:

09 October 2008, pp 423-428
- Chapter
- - Get access
    
    Check if you have access via personal or institutional login
    
    Log in Register
- Export citation
Summary

The association of elevated hematocrit and fibrinogen levels with increased stroke risk has led to continued interest in hemorheologic factors and their role in the development of vascular disease and acute stroke. Viscosity increases logarithmically at the lowest shear rates and this effect is magnified at higher hematocrit levels. Fibrinogen may play a causal role in ischemic stroke through several mechanisms. The most prominent of these is its essential role in thrombosis, both as the substrate for fibrin clot formation and as a facilitator of platelet aggregation. The risk of stroke in sickle cell disease (SCD) varies according to genotype and is highest in patients with homozygous SS. Plasma hyperviscosity syndromes are treated by plasmapheresis (plasma exchange) to remove the paraproteins and thereby reduce hyperviscosity and hypervolemia. Newer techniques of cell centrifugation, plasma separation, and filtration may also be useful.

Search Results

Refine search

Refine search

Actions for selected content:

1 results

58 - BONE DISORDERS AND CEREBROVASCULAR DISEASES

Summary

Search Results

Refine search

Refine search

Actions for selected content:

Save Search

1 results

58 - BONE DISORDERS AND CEREBROVASCULAR DISEASES

Summary