In Ghana, persons below 18 years of age are presumed to be children and vulnerable, and are expected to enjoy special protection and care against all hazards, even if they go against the law. This agrees with Ghana’s legal provision and other international legal documents. This study examined the knowledge of the police and their relationship with children in conflict with the law in Ghana using the Northern Region as a case study. Primary data were generated through interviews and questionnaire administration from a combined 219 participants who were purposely and systematically selected in a convergent mixed-methods design. The study found good knowledge of the police as to who a child in conflict with the law was (76%), yet only 40% rightly knew the criminal capacity of a child. The study revealed that the rights of children in conflict with the law, such as non-torture, access to legal assistance and right to safe custody, were flouted.