Thirty studies published between 1977 and 2001 that focus on outcome
following unruptured intracranial aneurysm (UIA) treatment are
reviewed. Although findings from these studies suggest outcome from UIA
treatment is reasonably good (between 5% and 25% morbidity and between
0–7% mortality), many of the complex issues associated with the
treatment of UIAs remain controversial. Most of the studies reviewed
address outcome in terms of mortality and neurological morbidity. Very
few studies exist which include measures of outcome such as cognitive
status, psychosocial functioning and quality of life. Given that
patients facing treatment tend to be healthy middle-aged adults with
many years of active working and social life ahead of them, it is
important to take into account the long-term consequences of either
harboring an UIA, or having it treated. The small number of studies
that include cognitive, psychosocial and quality of life outcomes are
reviewed in some detail and suggestions made for improving future UIA
outcome research. (JINS, 2004, 10,
114–134.)