This article examines relations between the Orthodox Church of Cyprus and the British colonial government during the First World War. I argue that the Great War constituted the first turning point in Church-State relations during colonial rule in Cyprus which, following other developments, finally collapsed during the 1950s. I discuss how the dynamic of the Enosis movement for the union of Cyprus with Greece was bolstered during the Great War. This in turn, the article will show, had significant repercussions on the attitudes of the Orthodox Church and the British authorities, transformed their relationship and opened the way for future developments.