This study examines precipitation samples collected at the Yushu meteorological station on the eastern Tibetan Plateau from November 2000 to November 2002. Results show that air-temperature effects control δ18O in precipitation in this area. Values of δ18O in precipitation positively correlate with air temperature, especially for monthly averages. Our data also show δ18O values in precipitation positively correlate with dew point and surface pressure in the Yushu region. Similar to other stations (Tuotuohe, Nagqu, Gaize and Shiquanhe) lying in the transition zone between the regions in the south dominated by the monsoon and those in the north dominated by the westerlies, because of the effect of monsoon precipitation, precipitation rates are high, and heavy isotopes are more depleted in summer at the Yushu station. Accordingly, values of δ18O in precipitation correlate more strongly with air temperature and dew point before the monsoon onset and after the monsoon retreat than during the monsoon period. That is, intense monsoon activities weaken the correlations between δ18O and air temperature and dew point. Clearly, dew point, surface pressure and the monsoon intensity contribute to controlling the δ18O values in precipitation at the Yushu station.