Richtmyer–Meshkov instability (RMI) at a light–heavy single-mode interface over a wide range of post-shock Atwood numbers $A_1$ is studied systematically through elaborate experiments. The interface generation and $A_1$ variation are achieved by the soap-film technology and gas-layer scheme, respectively. Qualitatively, the nonlinear interface evolution features, including spike, bubble and roll-up structures, are more significant in RMI with higher $A_1$. Quantitatively, both the impulsive model and an analytical linear model perform well in predicting the linear growth rate under a wide range of $A_1$ conditions. For the weakly nonlinear stage, the significant spike acceleration occurring when $A_1$ is high, which is observed experimentally for the first time, results in the evolution law of RMI with high $A_1$ being different from the counterpart with low or intermediate $A_1$. None of the considered nonlinear models is found to be applicable for RMI under all $A_1$ conditions, and the predictive capabilities of these models are analysed and summarized. Based on the present experimental results, an empirical nonlinear model is proposed for RMI over a wide range of $A_1$. Further, modal analysis shows that in RMI with high (low or intermediate) $A_1$, high-order harmonics evolve rapidly (slowly) and cannot (can) be ignored. Accordingly, for RMI with high (low or intermediate) $A_1$, the modal model proposed by Zhang & Sohn (Phys. Fluids, vol. 9, 1997, pp. 1106–1124) is less (more) accurate than the one proposed by Vandenboomgaerde et al. (Phys. Fluids, vol. 14, 2002, pp. 1111–1122), since the former ignores perturbation solutions higher than fourth order (the latter retains only terms with the highest power in time).