Sporadic clusters of healthcare-associated coronavirus disease 2019 (COVID-19) occurred despite intense rostered routine surveillance and a highly vaccinated healthcare worker (HCW) population, during a community surge of the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) B.1.617.2 δ (delta) variant. Genomic analysis facilitated timely cluster detection and uncovered additional linkages via HCWs moving between clinical areas and among HCWs sharing a common lunch area, enabling early intervention.

This study topologically describes near-wall flows around a surface-mounted cylinder at a high Reynolds number ($Re$) of $5\times 10^4$ and in a very thick boundary layer, which were partially measured or technically approximated from the literature. For complete and rational flow construction, we use high-resolution simulations and critical-point theory. The large-scale near-wake vortex is composed of two connected segments rolled up from the sides of the cylinder and from the free end. Another large-scale side vortex clearly roots on two notable foci on the lower side wall. In the junction region, the side vortex moves upwards with a curved trajectory, which induces the formation of nodes on the ground surface. In the free-end region, the side vortex is compressed, which results in a smaller trailing-edge vortex and its downstream movement. Only tip vortices are observed in the far wake. The origin of the tip vortices and their distinction from the near-wake vortex are discussed. Further analyses suggest that $Re$ independence should be treated with high caution when $Re$ increases from 500 to ${O}(10^4)$. The occurrence of upwash flow behind the cylinder strongly depends on the increase in $Re$, the mechanism of which is also provided. The separation–reattachment process in the junction region and the trailing-edge vortices are discovered only at a high $Re$. The former should significantly affect the strength of the side vortex in the junction region and the latter should cause a sharp drop in pressure near the trailing edge.

South-east Asia's diverse coastal wetlands, which span natural mudflats and mangroves to man-made salt pans, offer critical habitat for many migratory waterbird species in the East Asian–Australasian Flyway. Species dependent on these wetlands include nearly the entire population of the Critically Endangered spoon-billed sandpiper Calidris pygmaea and the Endangered spotted greenshank Tringa guttifer, and significant populations of several other globally threatened and declining species. Presently, more than 50 coastal Important Bird and Biodiversity Areas (IBAs) in the region (7.4% of all South-east Asian IBAs) support at least one threatened migratory species. However, recent studies continue to reveal major knowledge gaps on the distribution of migratory waterbirds and important wetland sites along South-east Asia's vast coastline, including undiscovered and potential IBAs. Alongside this, there are critical gaps in the representation of coastal wetlands across the protected area networks of many countries in this region (e.g. Viet Nam, Indonesia, Malaysia), hindering effective conservation. Although a better understanding of the value of coastal wetlands to people and their importance to migratory species is necessary, governments and other stakeholders need to do more to strengthen the conservation of these ecosystems by improving protected area coverage, habitat restoration, and coastal governance and management. This must be underpinned by the judicious use of evidence-based approaches, including satellite-tracking of migratory birds, ecological research and ground surveys.

We study the asymptotic behaviour of convective heat transfer for turbulent flows in high-porosity fluid-saturated media by two-dimensional high-resolution numerical simulation. The generalized Navier–Stokes equations for incompressible fluid flow and the heat transport equation in porous media at the representative element volume scale are solved by the lattice Boltzmann method, wherein the non-Darcian effects are taken into consideration. The asymptotic behaviour of the Nusselt number $N$ has been revealed for Rayleigh numbers $10^4\leq R\leq 10^{11}$ and Darcy numbers $10^{-6}\leq \xi \leq 10^6$: all the data for various Darcy numbers gradually collapse onto a unique line with increasing Rayleigh number. The asymptote can be well represented by $N=0.146\times R^{0.286}$ for $R>2\times 10^7$, which approaches the relationship for the Rayleigh–Bénard turbulent convection of free fluid flows. The transition can be characterized by a scaling analysis with $R^{}\xi ^{3/2}\sim 1$, below which, however, the data collapse onto the Darcy limit for porous media. The Reynolds number and the Nusselt number both increase with Darcy number above the onset of convection, whereas a premature saturation of the Nusselt number is observed in comparison with that of the Reynolds number. The counter-gradient heat transport by the large-scale flows is quantified, which compensates for the increase of the gradient heat transport with Darcy number. The heat transfer in high-porosity fluid-saturated media with a very small Darcy number $\xi \geq 10^{-6}$ can be comparable to that of free fluid flows for a sufficiently high Rayleigh number $R\geq 10^{11}$.

To investigate the effects of dietary fibre on follicular atresia in pigs fed a high-fat diet, we fed thirty-two prepubescent gilts a basal diet (CON) or a CON diet supplemented with 300 g/d dietary fibre (fibre), 240 g/d soya oil (SO) or both (fibre + SO). At the 19th day of the 4th oestrus cycle, gilts fed the SO diet showed 112 % more atretic follicles and greater expression of the apoptotic markers, Bax and caspase-3, and these effects were reversed by the fibre diet. The abundance of SCFA-producing microbes was decreased by the SO diet, but this effect was reversed by fibre treatment. Concentrations of serotonin and melatonin in the serum and follicular fluid were increased by the fibre diet. Overall, dietary fibre protected against high fat feeding-induced follicular atresia at least partly via gut microbiota-related serotonin–melatonin synthesis. These results provide insight into preventing negative effects on fertility in humans consuming a high-energy diet.

We aimed to evaluate the relationship of plasma Mg with the risk of new-onset hyperuricaemia and examine any possible effect modifiers in hypertensive patients. This is a post hoc analysis of the Uric acid (UA) Sub-study of the China Stroke Primary Prevention Trial (CSPPT). A total of 1685 participants were included in the present study. The main outcome was new-onset hyperuricaemia defined as a UA concentration ≥417 μmol/l in men or ≥357 μmol/l in women. The secondary outcome was a change in UA concentration defined as UA at the exit visit minus that at baseline. During a median follow-up duration of 4·3 years, new-onset hyperuricaemia occurred in 290 (17·2 %) participants. There was a significantly inverse relation of plasma Mg with the risk of new-onset hyperuricaemia (per sd increment; OR 0·85; 95 % CI 0·74, 0·99) and change in UA levels (per sd increment; β −3·96 μmol/l; 95 % CI −7·14, −0·79). Consistently, when plasma Mg was analysed as tertiles, a significantly lower risk of new-onset hyperuricaemia (OR 0·67; 95 % CI 0·48, 0·95) and less increase in UA levels (β −8·35 μmol/l; 95 % CI −16·12, −0·58) were found among participants in tertile 3 (≥885·5 μmol/l) compared with those in tertile 1 (<818·9 μmol/l). Similar trends were found in males and females. Higher plasma Mg levels were associated with a decreased risk of new-onset hyperuricaemia in hypertensive adults.

Geochronological, major and trace element, and Sr–Nd–Hf isotopic data are reported for the monzonitic rocks of the Fushan pluton in the Taihang Mountains, central North China Craton, in order to investigate their sources, petrogenesis and tectonic implications. Zircon U–Pb dating results reveal that the Fushan pluton was emplaced during the Early Cretaceous (∼126–124 Ma). The monzonites and quartz monzonites are mainly characterized by calc-alkaline and magnesian features and display light rare earth element (LREE) enrichment and flat heavy REE (HREE) patterns with slightly positive Eu anomalies. They have similar whole-rock initial 87Sr/86Sr ratios (0.70653–0.70819), εNd(t) values (−13.6 to −18.6) and zircon εHf(t) values (−21.8 to −17.3). The primary magma of the Fushan pluton was derived from the partial melting of a spinel-facies amphibole-bearing ancient enriched lithospheric mantle. The monzonitic rocks also have high Ba–Sr and low Y and Yb contents, with high Sr/Y and La/Yb ratios. These geochemical features of monzonitic rocks are not only inherited from the magma source but also significantly enhanced by crystal fractionation during magmatic evolution; e.g. hornblende fractionation increased the Ba–Sr concentrations and Sr/Y ratios. During the Early Cretaceous, the slab sinking and roll-back of the Palaeo-Pacific Plate could have created an ancient big mantle wedge beneath East Asia and induced a lithospheric extensional process in the central North China Craton within an intracontinental setting.

The present study was undertaken to investigate the antiparasitic activity of extracellular products of Streptomyces albus. Bioactivity-guided isolation of chloroform extracts affording a compound showing potent activity. The structure of the compound was elucidated as salinomycin (SAL) by EI-MS, 1H NMR and 13C NMR. In vitro test showed that SAL has potent anti-parasitic efficacy against theronts of Ichthyophthirius multifiliis with 10 min, 1, 2, 3 and 4 h (effective concentration) EC50 (95% confidence intervals) of 2.12 (2.22–2.02), 1.93 (1.98–1.88), 1.42 (1.47–1.37), 1.35 (1.41–1.31) and 1.11 (1.21–1.01) mg L−1. In vitro antiparasitic assays revealed that SAL could be 100% effective against I. multifiliis encysted tomonts at a concentration of 8.0 mg L−1. In vivo test demonstrated that the number of I. multifiliis trophonts on Erythroculter ilishaeformis treated with SAL was markedly lower than that of control group at 10 days after exposed to theronts (P < 0.05). In the control group, 80% mortality was observed owing to heavy I. multifiliis infection at 10 days. On the other hand, only 30.0% mortality was recorded in the group treated with 8.0 mg L−1 SAL. The median lethal dose (LD50) of SAL for E. ilishaeformis was 32.9 mg L−1.

Exchange rates influence a country's trading capability, foreign reserves and competitiveness. Recently, the exchange rate between the Chinese RMB and the U.S. dollar has been a contentious issue in both the United States and China. In this paper, we conduct a historical review of how the United States deployed negotiation strategies with China on the exchange rate issue and consider the degree to which it follows theoretical expectations. We then analyze the changing nature of the factors which shape exchange rate negotiations between the two nations in projecting alternative scenarios for the future of conflict resolution between the U.S. and China on this issue. We predict that the U.S. is likely to continue alternating between competition and collaboration, a negotiation cycle influenced by U.S. domestic politics, and China is less likely to continue with accommodation and compromise. The sequencing and timing of each nation's negotiation strategy will lead to widely divergent consequences for the management of exchange rates and the world economy.

For the first time, we estimated the population sizes of two swan species and four goose species from observations during the non-breeding period in East Asia. Based on combined counts from South Korea, Japan and China, we estimated the total abundance of these species as follows: 42,000–47,000 Whooper Swans Cygnus cygnus; 99,000–141,000 Tundra Swans C. columbianus bewickii; 56,000–98,000 Swan Geese Anser cygnoides; 157,000–194,000 Bean Geese A. fabalis; 231,000–283,000 Greater White-fronted Geese A. albifrons; and 14,000–19,000 Lesser White-fronted Geese A. erythropus. While the count data from Korea and Japan provide a good reflection of numbers present, there remain gaps in the coverage in China, which particularly affect the precision of the estimates for Bean, Greater and Lesser White-fronted Geese as well as Tundra Swans. Lack of subspecies distinction of Bean Geese in China until recently also limits our ability to determine the true status of A. f. middendorffii there, but all indications suggest this population numbers around 18,000 individuals and is in need of urgent attention. The small, highly concentrated and declining numbers of Lesser White-fronted Geese give concern for this species, as do the major declines in Greater White-fronted Geese in China (in contrast to numbers in Japan and Korea, considered to be a separate flyway). In the absence of any demographic data, it is impossible to interpret the causes of these changes in abundance. Improved monitoring, including demographic and tracking studies are required to provide the necessary information to retain populations in favourable conservation status.

Environmental filtering and competitive interactions are important ecological processes in community assembly. The contribution of the two processes to community assembly can be evaluated by shifts in functional diversity patterns. We examined the correlations between functional diversity of six traits (leaf chlorophyll concentration, dry matter content, size, specific leaf area, thickness and wood density) and environmental gradients (topography and soil) for 92 species in the 20-ha Dinghushan forest plot in China. A partial Mantel test showed that most of the community-weighted mean trait values changed with terrain convexity and soil fertility, which implied that environmental filtering was occurring. Functional diversity of many traits significantly increased with increasing terrain convexity and soil fertility, which was associated with increased light and below-ground resources respectively. These results suggest that co-occurring species are functionally convergent in regions of strong abiotic stress under the environmental filtering, but functionally divergent in more benign environments due to resource partitioning and competitive interactions. Single-trait diversity and multivariate functional diversity had different relationships with environmental factors, indicating that traits were related to different niche axes, and associated with different ecological processes, which demonstrated the importance of focusing niche axes in traits selection. Between 9% and 41% of variation in functional diversity of different traits was explained by environmental factors in stepwise multiple regression models. Terrain convexity and soil fertility were the best predictors of functional diversity, which contributed 30.5% and 29.0% of total R2 to the model. These provided essential evidence that different environmental factors had distinguishing impacts on regulating diversity of traits.

The analytical capacity models of an airport with two runways system are developed in this paper and the theoretical capacity curves yielded by this model are analysed. The statistic airport capacity estimation methodology based on historical data is introduced as well. Both analytical models and statistic strategy are applied to estimate the capacity of the two runways system of a typical airport. Two sets of airport capacity curves obtained in different ways are compared and analysed. The result of the analysis indicates that the mathematical model works effectively in a fairly accurate way in the estimation of airport capacity.

The mesoporous and nanorods SnO2 are synthesized by controlling the state of SnCl2·2H2O precursor with SBA-15 as hard template, and the possible formation mechanisms at different assembling modes inside the ordered mesoporous silica templates are proposed. In addition, SnO2 nanoparticles are synthesized by hydrolysis depositing method. The electrochemical tests of as-prepared samples indicate that the reticular stacking structure of the nanorods would limit the Li+ ions to intercalate, but the effect of volume expansion in this case upon cycling is insignificant. The mesostructure SnO2 tends to be stable after partial structural collapse at first few cycles. And the Li+ ions can readily intercalate and de-intercalate into/from its ordered channels structure, which provides a high capacity and an improved cycle property. Although SnO2 nanoparticles deliver high capacity at an early stage, the agglomeration may induce the capacity to drop rapidly after a certain number of cycles.