Nutritional Risk Screening index is a standard tool to assess nutritional risk, but epidemiological data are scarce on controlling nutritional status (CONUT) as a prognostic marker in acute haemorrhagic stroke (AHS). We aimed to explore whether the CONUT may predict a 3-month functional outcome in AHS. In total, 349 Chinese patients with incident AHS were consecutively recruited, and their malnutrition risks were determined using a high CONUT score of ≥ 2. The cohort patients were divided into high-CONUT (≥ 2) and low-CONUT (< 2) groups, and primary outcomes were a poor functional prognosis defined as the modified Rankin Scale (mRS) score of ≥ 3 at post-discharge for 3 months. Odds ratios (OR) with 95 % confidence intervals (CI) for the poor functional prognosis at post-discharge were estimated by using a logistic analysis with additional adjustments for unbalanced variables between the high-CONUT and low-CONUT groups. A total of 328 patients (60·38 ± 12·83 years; 66·77 % male) completed the mRS assessment at post-discharge for 3 months, with 172 patients at malnutrition risk at admission and 104 patients with a poor prognosis. The levels of total cholesterol and total lymphocyte counts were significantly lower in high-CONUT patients than low-CONUT patients (P = 0·012 and < 0·001, respectively). At 3-month post discharge, there was a greater risk for the poor outcome in the high-CONUT compared with the low-CONUT patients at admission (OR: 2·32, 95 % CI: 1·28, 4·17). High-CONUT scores independently predict a 3-month poor prognosis in AHS, which helps to identify those who need additional nutritional managements.

Chlamydia trachomatis (CT) infection has been a major public health threat globally. Monitoring and prediction of CT epidemic status and trends are important for programme planning, allocating resources and assessing impact; however, such activities are limited in China. In this study, we aimed to apply a seasonal autoregressive integrated moving average (SARIMA) model to predict the incidence of CT infection in Shenzhen city, China. The monthly incidence of CT between January 2008 and June 2019 in Shenzhen was used to fit and validate the SARIMA model. A seasonal fluctuation and a slightly increasing pattern of a long-term trend were revealed in the time series of CT incidence. The monthly CT incidence ranged from 4.80/100 000 to 21.56/100 000. The mean absolute percentage error value of the optimal model was 8.08%. The SARIMA model could be applied to effectively predict the short-term CT incidence in Shenzhen and provide support for the development of interventions for disease control and prevention.

In high power laser facility for inertial confinement fusion research, final optics assembly (FOA) plays a critical role in the frequency conversion, beam focusing, color separation, beam sampling and debris shielding. The design and performance of FOA in SG-II Upgrade laser facility are mainly introduced here. Due to the limited space and short focal length, a coaxial aspheric wedged focus lens is designed and applied in the FOA configuration. Then the ghost image analysis, the focus characteristic analysis, the B integral control design and the optomechanical design are carried out in the FOA design phase. In order to ensure the FOA performance, two key technologies are developed including measurement and adjustment technique of the wedged focus lens and the stray light management technique based on ground glass. Experimental results show that the design specifications including laser fluence, frequency conversion efficiency and perforation efficiency of the focus spot have been achieved, which meet the requirements of physical experiments well.

The Shen-Guang II Upgrade (SG-II-U) laser facility consists of eight high-power nanosecond laser beams and one short-pulse picosecond petawatt laser. It is designed for the study of inertial confinement fusion (ICF), especially for conducting fast ignition (FI) research in China and other basic science experiments. To perform FI successfully with hohlraum targets containing a golden cone, the long-pulse beam and cylindrical hohlraum as well as the short-pulse beam and cone target alignment must satisfy tight specifications (30 and $20~\unicode[STIX]{x03BC}\text{m}$ rms for each case). To explore new ICF ignition targets with six laser entrance holes (LEHs), a rotation sensor was adapted to meet the requirements of a three-dimensional target and correct beam alignment. In this paper, the strategy for aligning the nanosecond beam based on target alignment sensor (TAS) is introduced and improved to meet requirements of the picosecond lasers and the new six LEHs hohlraum targets in the SG-II-U facility. The expected performance of the alignment system is presented, and the alignment error is also discussed.

Previous studies have investigated the association between dietary inflammatory potential and the development of cancer. For breast cancer the results have been equivocal. The present study aimed to investigate whether higher Dietary Inflammatory IndexTM (DII) scores were associated with increased risk of breast cancer among Chinese women. A total of 867 cases and 824 controls were recruited into the present case–control study from September 2011 to February 2016. DII scores were computed based on baseline dietary intake assessed by a validated 81-item FFQ. The OR and 95 % CI were assessed by multivariable logistic regression after adjusting for various potential confounders. DII scores in this study ranged from −5·87 (most anti-inflammatory score) to +5·71 (most proinflammatory score). A higher DII score was associated with a higher breast cancer risk (adjusted ORquartile 4 v. 1 2·28; 95 % CI 1·71, 3·03; adjusted ORcontinuous 1·40; 95 %CI 1·25, 1·39). In stratified analyses, positive associations also were observed except for underweight women or women with either oestrogen receptor+ or progesterone receptor+ status (but not both). Results from this study indicated that higher DII scores, corresponding to more proinflammatory diets, were positively associated with breast cancer risk among Chinese women.

Jacobsoniidae, comprising a small group of small-to-minute polyphagan beetles, is a family presently placed within Derodontiformia. No fossil jacobsoniid has been described to date. Here, we describe the first fossil jacobsoniid, Derolathrus groehni n. sp., based on two well-preserved individuals in middle Eocene Baltic amber. Micro–computed tomography (micro-CT) was used to reveal many diagnostic characters of the Recent genus Derolathrus Sharp. Derolathrus groehni is compared with modern Derolathrus species and is noteworthy for the well-developed eyes and elongate prothorax.

New-type oilseed rape (Brassica napus, ArArCcCc) with introgressed exotic subgenomic components from Brassica rapa (ArAr) and Brassica carinata (BcBcCcCc) showed strong heterosis in both vegetative and reproductive growth. The aim of the current study was to analyse the tolerance of the new-type B. napus with different exotic subgenomic contents to low nitrogen (N) stress. Under hydroponic culture and pot experiments, root system parameters, photosynthetic parameters, relative chlorophyll concentration (SPAD values), biomass, seed yield, seed yield components, N concentration and expressions of genes involved in N transport and assimilation were determined with two new-type B. napus genotypes (N-efficient genotype D4-15 and N-inefficient genotype D1-1) under high-N and low-N levels. Furthermore, N accumulation, N transfer efficiency and N use efficiency (NUE) were analysed in the two genotypes. The hydroponic and potted growth tests showed consistent characteristics in N uptake and utilization efficiency at the seedling stage, and N-efficient genotype (D4-15) showed better growth phenotypes across cultured conditions and N levels. Under the low-N condition, D4-15 produced a larger root system and accumulated more N, and had higher N transfer efficiency and NUE than D1-1. Moreover, D4-15 had significantly higher photosynthetic parameters, photosynthetic NUE and expression levels of the N transporter genes, BnNRT1·1, BnNRT2·5, BnNRT2·7 and BnAMT1·1, in roots or leaves, as well as higher seed yield than that of D1-1 under low-N supply. These results indicated that the N-efficient new-type B. napus D4-15 possessed excellent adaptability to low-N stress, which may be attributed to the highly introgressed exotic subgenomic components from B. rapa and B. carinata, suggesting the possibility of identifying high-nutrient-efficiency germplasm from inter-specific hybrids.

In this paper, we extend corresponding theory which can only deal with thin medium based on thin sheet approximation to a new area which can deal with thick medium with gain and loss. An analytical expression for the location and the peak intensity of the hot-image in the case of thick nonlinear medium with gain and loss are deduced by using propagation matrix method. In order to confirm our analysis as a reliable tool to forecast the hot-image damage risk, we provide some numerical results to verify its validity. The predictions of the theory are found to be in good agreement with the numerical simulations. The theoretical analysis can be used for forecasting the intensity and location of the hot-image. It can provide rules for estimating the damage risk of the hot-image and warn us of the critical areas that may be vulnerable to the hot-image.

Single-crystal SnO2 nanofibers have been formed from SnO2 polycrystals via reaction at low oxygen partial pressures. Polycrystalline SnO2 disks coated with Au nanoparticles were exposed to humid H2/N2 at 700 to 800 °C. Single-crystal SnO2 nanofibers formed beneath Au nanoparticles, with the nanofiber length oriented parallel to the [100] crystallographic direction of SnO2. Because this simple process does not require either a separate source of a Sn–O-bearing vapor species located upstream of the substrate or a temperature gradient, single-crystal nanofibers may be formed on large area SnO2-bearing substrates.

This paper investigates the effects of consistent and inconsistent long-run variance estimation on a test for a unit root, based on the generalization of the von Neumann ratio. The results from the Monte Carlo experiments suggest that the unit root tests based on an inconsistent estimator have less size distortion and more stability of size across different autocorrelation specifications as compared to the tests based on a consistent estimator. This improvement in size property, however, comes at the cost of a loss in power. The finite-sample power, in addition to the local asymptotic power, of the tests with an inconsistent estimator is shown to be much lower than that of conventional tests. This finding can be well generalized to the test for cointegration in a multivariate system. The paper also points out that combining consistent and inconsistent estimators in the long-run variance ratio test is one possibility of balancing the size and power.The authors thank two anonymous referees, Pentti Saikkonen, and participants of the 2004 Midwest Econometrics Group meetings, 2005 Spring Meetings of The Japanese Economic Association, and a workshop at Vanderbilt University for helpful comments and suggestions.

Non-oxide ceramic materials like boron carbide and silicon carbide are technologically relevant as advanced high temperature materials, while boron nitride is a thermally robust low-k insulating material with electronic applications. Efficient routes to boron carbide, boron nitride, and silicon carbide ceramic nanostructures have been developed which employ molecular and polymeric precursors, including the boron carbide precursor 6, 6'-bis(decaboranyl)hexane, the boron nitride precursor polyborazylene, and a commercially available silicon carbide precursor allylhydridopolycarbosilane(AHPCS), in conjunction with colloidal silica and biological silica “diatom” templates. Layered submicron-sized ordered void structures with three-dimensional periodicity and tunable length scales were fabricated by the melt infiltration of the precursors into ordered colloidal silica bead templates. Pyrolytic ceramic conversion followed by dissolution of the silica beads by chemical treatment with aqueous HF or NaOH generated highly uniform ceramic structures with thicknesses up to 50μm and ordered voids ranging in diameter from 50-150 nm. Following on earlier work by Sandhage who generated polymer and oxide ceramic structures, vacuum filtration of the ceramic precursor solutions through bioclastic silica diatom frustule templates generated polymer coated replicas of their 3-D micro- and nanostructures. Subsequent pyrolysis and dissolution of the frustules in 48% HF yielded free-standing ceramic structures with fine features on length scales of 60-200 nm. This technique therefore provides a large scale route to nano- and micro structured non-oxide ceramic materials. Structural control of the end products was achieved by changing the concentration of the precursor solution, pore size and/or the frustule template. Characterization by XRD, DRIFT, SEM, TEM and possible uses of these uniform nano- and micro-structured ceramics will be discussed.

Microscale zirconia structures with intricate three-dimensional (3D) shapes and nanoscale features were synthesized using diatom (single-celled algae) microshells as transient scaffolds. After exposure to a zirconium alkoxide-bearing solution and firing at 550–850 °C, silica-based diatom microshells were coated with a thin, continuous nanocrystalline zirconia layer. Predominantly tetragonal or monoclinic zirconia could be produced with appropriate heat treatments. Selective silica dissolution then yielded freestanding zirconia micro-assemblies that retained the microshell shape and fine features. Such hybrid (biological/synthetic chemical) processing may be used to mass-produce nanostructured micro-assemblies with a variety of 3D, biologically replicable shapes and tailored compositions for use in numerous applications.